Chordoma, an oddity for years, remains a baffling and defiant tumor. Despite the surge in studies and the advancements of imaging and techniques, chordoma is still plagued by unpredictability and…

Lesions involving the clivus represent a challenge to neurosurgeons due to its depth and close relationship with vital structures. The localization of chordomas at the middle of the skull base…

Chordoma of the spine generally presents with back pain, whereas neurologicsymptoms and other manifestations of mass effect, such as tracheal or esophageal compression, are less frequent. 1 Grossly, chordoma is…

The cranio-orbital–zygomatic (COZ) approach is the most versatile approach that can be used on selective cases of giant extensive chordomas that otherwise might need more than one approach or are…

Chordomas are very rare bone tumors. Data from the early 2000’s shows that their incidence rate is 0.1/100,000/year. Median age of presentation is 60 years. Unfortunately, skull base chordomas affect…

Chordomas are developmental tumors that arise from remnants of the notochordal tissue that is located at the center of the axial skeleton. Location at the skull base, the spine, and…

The middle fossa approach to the skull base is one of the most versatile approaches and follows the paramount principles of skull base surgery: avoiding brain retraction, shortening the distance,…

Origin and Occurrence The craniovertebral junction, along with the clivus, is a common site of neoplastic, vascular, and degenerative diseases, which often demand surgical treatment. 1,​2,​3,​4,​5,​6,​7 Chordomas are rare neoplasm,…

Chordomas and chondrosarcomas are divergent tumors, based on their immunohistologic features. They share some similarities with regards to anatomical location, clinical presentation, radiologic findings, and treatment options.1 Their names may…

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