US Editor: Raj Singh, M4, SUNY Downstate Health Sciences University, Brooklyn, New York
Brief overview
The behavior of people with Asperger syndrome is characterized by:
Rigid, obsessive-pedantic, and stereotypical patterns of action in combination with a lack of empathy.
The intelligence quotient of patients with Asperger’s is average to above average, often with special interests (insular talent) or skills.
Boys are more frequently affected than girls on the basis of the patient’s own and others’ medical history. Early childhood development and psychopathological findings, including behavioral patterns, are taken into account.
The treatment of Asperger syndrome is complex and usually multi-professional, with the aim of promoting the social skills of those affected.
In the ICD-10, Asperger syndrome and early childhood autism are classified as profound developmental disorders.
In the ICD-11, Asperger syndrome is no longer listed as a separate entity and is instead assigned to the new diagnosis of autism spectrum disorders.
Definition
Asperger syndrome
In the ICD-10, Asperger’s syndrome is classified as a profound developmental disorder with onset in childhood, characterized by:
Impaired social interaction and communication patterns
A restricted and stereotyped repertoire of interests and activities.
Note: There is no general developmental delay, and often a normal to above-average IQ.
In the ICD-11, Asperger syndrome is no longer listed as a separate entity and is under the umbrella of autism spectrum disorders.
Research findings over the last few decades have not confirmed the classification of early childhood autism and Asperger syndrome as two disease entities according to ICD-10. Instead, a continuum of symptoms with an overall heterogeneous etiology should be assumed.
Epidemiology
Prevalence figures vary due to shifting definitions and clinical criteria.
The prevalence of autism spectrum disorders is currently estimated at 0.9 to 1.1%.
ASD is diagnosed approximately four times more frequently in boys than in girls, and earlier studies on Asperger’s syndrome had shown a male:female gender ratio of 8:1.
You can read more about the epidemiology of autism spectrum disorders here.
Etiogenesis
The etiopathogenesis is still unknown:
There is a constitutional variant with familial clustering (genetic factors) in the male line.
Accompanying phenomena such as fine motor clumsiness or epileptic seizures suggest an organic brain component.
The underlying neuropsychological disorder is thought to be a weakness in empathy (“theory of mind”) and an impairment of executive functions (flexible planning), the mirror neuron system, and context recognition.
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