NEUROLOGY

Molecular Imaging in Neuroblastoma

Apr 6, 2019 by in NEUROLOGY Comments Off on Molecular Imaging in Neuroblastoma

Abstract Neuroblastoma is the most common malignancy in infancy and the most common extracranial solid tumor in the pediatric age group. There is only approximately 30%–40% long-term survival rates among…

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Novel Therapeutic Targets in Neuroblastoma

Apr 6, 2019 by in NEUROLOGY Comments Off on Novel Therapeutic Targets in Neuroblastoma

Abstract This chapter introduces the molecular targeted therapies and immunotherapies currently in use to treat neuroblastoma, which is the most common extracranial solid tumor in children. It presents a clinical…

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Targeting Angiogenesis in Neuroblastoma

Apr 6, 2019 by in NEUROLOGY Comments Off on Targeting Angiogenesis in Neuroblastoma

Abstract Antiangiogenic strategies are currently in use for the treatment of cancer, and the inhibition of angiogenesis could represent a powerful adjunct to traditional therapy of malignant tumors. Over the…

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Advances in the Surgical Treatment of Neuroblastoma

Apr 6, 2019 by in NEUROLOGY Comments Off on Advances in the Surgical Treatment of Neuroblastoma

Abstract The management of neuroblastoma requires a multidisciplinary approach led by the pediatric surgeon. Surgical biopsy and resection are essential to characterize the tumor, stratify patient risk, and guide the…

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Immunotherapy for Neuroblastoma

Apr 6, 2019 by in NEUROLOGY Comments Off on Immunotherapy for Neuroblastoma

Abstract Current therapeutic approaches for high-risk neuroblastoma include dose-intensive chemotherapy, surgical and radiotherapeutic interventions that are associated with long- and short-term toxicities. Immunotherapy utilizes mechanisms of action that are not…

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Current Pharmacotherapy for Neuroblastoma

Apr 6, 2019 by in NEUROLOGY Comments Off on Current Pharmacotherapy for Neuroblastoma

Abstract Neuroblastoma is, at once, a common and a frequently deadly cancer seen almost exclusively in children. The prognosis for patients with neuroblastoma is best in those whose tumor burden…

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