iNPH
AD
HC
Cutoff
Neuropsychological assessment
Mini Mental State Examination
18.8 (±6.7) ** ###
16.5(±4) ****
27(±2)
0–30
Mental assessment battery
RAVLT immediate
25.8 (±5) **
22.4(±5) ****
39 (±9.3)
>28.53
RAVLT delayed
4.87(±2.4) *** #
3(±2) ****
10(±2)
>4.69
RAVLT recognition
9(±2)
6(±3)
13.4(±1.5)
0–15
Episodic memory
8(±3) #
4.6(±2.2) **
11(±4.4)
0–28
Immediate visual memory
15.7(±2.7) ##
12.6(±4.6) ***
19(±3)
0–22
Raven’s Colored Progressive Matrices
18(±5.4) *
16(±6.4) ***
27(±5.3)
>18.96
Semantic verbal fluency
11. 3(±3) *
9.3(±3.5) ***
18(±5)
>7.25
Phonological verbal fluency
18.3(±12) **
17.2(±10) **
35.3(±9.4)
>17.35
Phrase construction
13.7(±8) ** ##
5(±5) ****
23(±3)
0–25
Copy drawing
5.5(±3) * #
4(±2.7) ***
9.3(±1.2)
>7.17
Copy drawing with landmarks
54.5(±7.2) **
35.3(±26) ***
66.5(±4)
>61.85
Frontal Assessment Battery
9(±4) #
9(±5.6) *
14(±3.4)
>12.03
Table 2
Frequencies of different mistakes in iNPH and AD patients
iNPH | AD | Fisher test | |
|---|---|---|---|
Primacy effect | 10 | 2 | p = 0.03 |
Recency effect | 10 | 10 | – |
Tendency to produce intrusions during free recall of words | 10 | 24 | – |
Tendency to produce false alarms during delayed recognition of words | 21 | 95 | p = 0.001 |
Globalistic responses | 0 | 22 | p = 0.0003 |
Odd responses | 4 | 42 | p = 0.01 |
Positional preference responses | 134 | 53 | – |
Inaccuracy on the Deux Barrage test | 1 | 8 | p = 0.0001 |
Occurrence of closing-in phenomenon | 1 | 53 | p = 0.001 |
Table 3
Neuropsychological performance in 12 iNPH patients on admission, and after surgical treatment in 7 patients
