Clinical Assessment of Children and Adolescents With Depression
CARLO G. CARANDANG
ANDRÉS MARTIN
KEY POINTS
Although the core symptoms of depression are similar across the life span, developmental differences exist and should be taken into account in the assessment.
With increasing age, there generally is an increase in melancholic symptoms, delusions, and suicidal ideation and attempts. In contrast, younger children tend to have more separation anxiety, behavior problems, temper tantrums, and hallucinations.
Direct interviews with children and adolescents are critical because parents and teachers may not be aware of the youth’s depressive symptoms.
Discrepant information between parents and their children should be solved in a cordial and nonjudgmental way.
Assessment of suicidal and homicidal ideation and behaviors is mandatory.
The interview process and screening questions used by research interviews, such as the Schedule for Affective Disorders and Schizophrenia for School Age Children, Present and Lifetime Version (KSADS-PL), can be useful.
Detection and diagnosis can be enhanced by using parent and child self-report measures.
Introduction
The preceding chapters focused on the phenomenology, etiology, course, and prognosis of children and adolescents with depression. This chapter presents a practical approach to evaluating young persons for depression. As such, we focus on the “how to” rather than on the “what is” of pediatric depression. Much of what we do as clinicians is not exclusively informed by evidence or hard data. In the end, unless a connection is made with our young patients and their families and unless we master the process of assessing pediatric depression, no amount of evidence will be applied to its fullest.
The goals of assessment are to (1) establish if the patient suffers from psychiatric disorders and, if so, which ones, (2) elicit the factors that may have caused or contributed to the initiation of these problems and to their persistence (genetic, developmental, familiar, social), (3) evaluate patients’ normal level of functioning and the extent this has been impaired by the illness, (4) identify areas of strength as well as potential supports within the family and the wider social environment, and (5) build trust and rapport. It is assumed that you are familiar with a psychiatric evaluation and aware that the interview is the main tool in assessing patients, based not only on what patients and families disclose but also by observing their behavior and interactions—with the clinician, family members, toys, and others.
Assessment of a child or adolescent differs from that of an adult in several respects. Whereas most adults seek help on their own behalf, children rarely do so. As a result, parents or caregivers are often the primary source of information. Greater emphasis is placed on corroborative history from teachers
or other persons who know the patient. Also, the developmental level of the child has to be taken into account when considering symptoms and functioning. However, it is similar to assessing adults in that it requires clinicians to obtain a detailed history, to conduct a mental status examination (and a physical examination when necessary), to integrate all the data in a formulation, diagnosis, and differential diagnosis, to convey this information back to patients and family, and to negotiate a plan for treatment.
or other persons who know the patient. Also, the developmental level of the child has to be taken into account when considering symptoms and functioning. However, it is similar to assessing adults in that it requires clinicians to obtain a detailed history, to conduct a mental status examination (and a physical examination when necessary), to integrate all the data in a formulation, diagnosis, and differential diagnosis, to convey this information back to patients and family, and to negotiate a plan for treatment.
Assessment of young persons typically requires more time than adults (2 to 5 hours). Briefer assessment is undertaken in an emergency, but this is usually followed by more extensive evaluation at a later point. Dealing with families also requires specific skills and techniques, which are described in Chapter 10.
As discussed in Chapter 1, two classification systems are used for diagnosis: the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV),1 and the World Health Organization’s International Classification of Diseases, 10th edition (ICD-10).2 We refer to the DSM-IV in this chapter, in line with the rest of the book. The focus is on the DSM-IV depressive disorders, which include major depressive disorder and dysthymic disorder. The word youth and young person are used to refer to both children and adolescents. The word depression is used to refer to both major depressive disorder and dysthymia.
GENERAL RECOMMENDATIONS ABOUT ASSESSMENT
The initial evaluation involves obtaining data from multiple sources, which include the youth, parents, and teachers. This comprises interviews with the youth alone (and, if indicated, the parents alone) and interviews with both the youth and parents.
Confidentiality should be discussed at the onset. This includes explaining that information will be kept confidential unless the patient’s life or other persons’ lives are at risk. The role of clinicians as mandated reporters of abuse (in most countries) should also be explained. Because child protection is paramount, disclosures of abuse to the clinician from the child or others need to be shared with the local child protection agency. Sensitive issues such as substance abuse, sexual activity, and pregnancy would not warrant breaking confidentiality unless there are special circumstances; it is better to encourage the youth to share this information with the parents. In the United States (according to the Health Insurance Portability and Accountability Act), it should be explained that the government has the right to access patients’ medical records. Youth and parental consent to contact other informants (e.g., teachers) should also be obtained.
CONDUCTING THE ASSESSMENT INTERVIEW
The youth interview is critical because parents and teachers tend to underreport depressive symptoms.3 Clinicians differ in their view about how this should be achieved; some prefer seeing adolescents first and then together with the parents—or parents alone, if one expects too much conflict. For children, the opposite is often preferred: to see the child together with parents or parents alone first, and then interviewing the child alone. Children are less likely to answer questions reliably about mood, time concepts, comparing themselves to their peers, and questions that require the child to use judgment.4 Interviewing the parent first allows the eliciting of relevant information and the time course of symptoms, which can be used later when interviewing the child.5 For example, the interviewer can start by stating that parents have described periods when the child looks sad or angry, and asking the child to describe the feelings during these times, or having the child point to a face on a chart with a variety of expressions/emotions. This can help children with chronological data (e.g., “your parents said you have been sad since the New Year” rather than “tell me about your moods over the last 2 months.”). Questions need to be simple (e.g., dealing with one concrete issue at a time: “Have you been feeling so bad that you have been crying often in the last few days?”), not long or complicated (e.g., several issues in one question: “Have you been feeling sad, having problems sleeping, or not concentrating at school?”). Avoid leading questions (more likely to draw “yes” answers and more false positives) and vague, open-ended questions (more likely to draw “I don’t know” answers and more false negatives).
Many adolescents prefer to be interviewed alone first. Adolescents value their privacy and independence and are more likely to share information if they know it will be kept confidential.
Clinicians should outline the parameters by which they will share information with the parents, which mainly includes safety issues, such as suicidal and homicidal thoughts. The youth should also be made aware that disclosures of abuse will result in a call to local child protective services. Contrary to popular views, asking about suicide will not induce or trigger the youth to commit suicide. Young persons are often relieved when a caring clinician asks about their suicidal thoughts.
Clinicians should outline the parameters by which they will share information with the parents, which mainly includes safety issues, such as suicidal and homicidal thoughts. The youth should also be made aware that disclosures of abuse will result in a call to local child protective services. Contrary to popular views, asking about suicide will not induce or trigger the youth to commit suicide. Young persons are often relieved when a caring clinician asks about their suicidal thoughts.
Gaining the trust of depressed young persons is often a challenge; however, without trust, valid information is less likely to be obtained. Apathy (“sure, whatever”) and withdrawal (no eye contact, no talking) are common responses. Starting with favorite hobbies or pleasurable topics is often helpful to get the young person talking. Finding a common interest between clinician and young person is even better, with care not to overdo it.
Parents can be interviewed alone if sensitive information needs to be discussed. The interview with the parents should focus on the patient’s depressive and other symptoms, antecedent triggers, school and social functioning, and family history. Opening a “Pandora’s box” is not the goal of an initial assessment.
After the interviews with the patient and family, if the case is difficult or complex, it may be helpful to debrief with a colleague. It is useful to spend some time processing the information, considering the differential diagnoses and treatment, and scoring rating scales. Once a provisional diagnosis and treatment plan are formulated, the clinician can debrief the patient and parents. Psychoeducation is often the focus at this stage because the family usually has questions regarding diagnoses, prognosis, and treatment.
RECONCILING CONFLICTING DATA AMONG PARENT, YOUTH, AND OTHER SOURCES
Many instances arise when youth give opposite information to their parents. Further inconsistencies can come from other sources, such as teachers, friends, and medical records. Basically the clinician needs to meet together with the child and parent(s) and in a nonjudgmental way resolve discrepancies. Clinicians can also use either the “best-estimate diagnoses” or the “or” rule to reconcile differences.
The best estimate diagnosis is the process by which clinicians synthesize all available data, resolve discrepancies between data sources, and use their clinical judgment to arrive at the final diagnosis.6 Using guidelines to resolve discrepancies between data sources results in good to excellent test-retest reliability. These include the following:7
Data from direct interviews are given more weight than to other reports.
When data are limited regarding family history, positive reports receive greater weight than negative reports.
Regardless of source, positive reports of symptoms in excess of the minimum requirements to meet diagnostic criteria receive more weight than positive reports of symptoms that barely meet criteria.
Symptoms supported by more convincing examples should be given more weight than those supported by vague or ambiguous examples.
Data from informants with greater contact with the patient are given more weight than from those with less contact.
Another method to resolve discrepancies is the “or” rule, where a symptom is counted toward the criteria if either the parent or youth endorses the symptom. The “or” rule maximizes sensitivity at the cost of specificity8 and may be useful in cases in which young persons minimize symptoms. However, this method may result in an increase in the number of comorbid diagnoses.
DETECTING DEPRESSION IN CHILDREN AND ADOLESCENTS
Detecting depression can be difficult because depressed youth are often dismissed as having problems related to bad behavior, or their behavior is attributed to a “phase” of development such as adolescent angst. Table 3.1 outlines common presentations.
TABLE 3.1 PRESENTATIONS AND CIRCUMSTANCES THAT SHOULD RAISE SUSPICIONS OF MAJOR DEPRESSION | ||||||
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Sustained Negative Mood Change
One of the key factors is duration: The mood problem (irritability, sadness, anhedonia) lasts most of the day (e.g., more than half the time awake) and for most days of the week, with a minimum duration of 2 weeks (in practice, many clinicians and researchers prefer a longer duration, e.g., 4 weeks). Children often have trouble verbalizing their own feelings or deny feelings of sadness or irritability. The clinician should then rely on other informants and on observable behaviors (e.g., tearfulness) to complete the assessment.
Suicidality
Many youth who show suicidal behavior suffer from depression. Suicide is the leading preventable cause of death in young persons 15 to 24 years of age in the developed world. Many completed suicides are related to psychiatric illness, particularly mood disorders associated with impulsivity, history of abuse, and substance use9 (see also Chapter 15).
Excessive Somatic Complaints
Frequent visits to the school nurse or the pediatrician because of somatic complaints that are in excess of what is to be expected with a particular medical illness may be a telltale sign of depression. Children and developmentally delayed youths with depression often present with excessive somatic complaints. This may also be secondary to anxiety that often accompanies depression.
Behavior Problems
Severe, recurrent temper tantrums above and beyond what would be expected for the developmental stage can be a manifestation of depression in children and adolescents. Conduct problems and oppositional behavior can also be a sign of depression. A marked and persistent change of behavior in a child or adolescent when there was no disruptive conduct previously should raise a red flag for depression.
Drop in School Performance
Depression affects young persons’ ability to focus on schoolwork and the motivation to complete it. Problems with sleep-wake cycle associated with depression may contribute to youth missing classes or, in severe cases, stopping school attendance altogether. Some eventually drop out of school. Thus it is important to follow-up depressed youth who are in school and those who have dropped out of school.
Relationship Problems, Family Conflict
Problems with peers and family can both trigger or be the result of a depressive episode (see Chapters 2 and 10).
Drug Abuse
Young persons with depression often resort to drugs to feel better. Substance use greatly increases the risk for suicide; all substance-abusing adolescents should be screened for depression (see also Chapter 18).
Family History of Depression
The offspring of depressed parents are at increased risk of depression (see Chapter 2). Thus a positive family history should raise suspicions that the youth may have this disorder. However, offspring of depressed parents are also at risk of developing other disorders such as anxiety and attention deficit hyperactivity disorder (ADHD).
Being Bullied or Abused
Bullying and physical, emotional, or sexual abuse can trigger or exacerbate a depressive episode.
ASSESSING DEPRESSIVE EPISODES AND DIAGNOSING DEPRESSIVE DISORDERS
Mnemonics, such as SIGECAPS, are helpful to remember the DSM-IV criteria for mood disorders. Table 3.2 lists what each letter of the mnemonic stands for and examples of developmentally-appropriate questions to elucidate each symptom.10
TABLE 3.2 MNEMONIC FOR MAJOR DEPRESSIVE EPISODE IN ADDITION TO DEPRESSED MOOD (SIGECAPS) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
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To meet DSM-IV criteria for a major depressive episode, at least five out of the nine symptoms should have been present for at least 2 weeks; one of the symptoms being either depressed mood or anhedonia (loss of interest or pleasure). Except for depressed mood, the other criteria for a major depressive episode are contained in the mnemonic SIGECAPS.
It is important to assess the current (or most recent) depressive episode as well as prior depressive episodes, and to evaluate their severity (Table 3.3). This is important because treatment for a single episode differs from that of recurrent depression, and treatment for mild to moderate depression is different from severe depression. Mood charts (see Resources for Families section) can be helpful to map out depressive episodes, illustrating frequency or number of episodes, triggers, duration, and severity.
TABLE 3.3 RATING SEVERITY OF DEPRESSIVE EPISODE1 | ||||||||||||
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Episodicity is a critical characteristic of subjects with mood disorders, although a minority may have chronic symptoms (see Chapter 1). However, a common error is to make a diagnosis of “major depressive episode.” The correct diagnosis is “major depressive disorder,” single or recurrent episode, and mild, moderate, or severe.
Dysthymic disorder is diagnosed using the same mnemonic for depression, except that the last two criteria (psychomotor agitation/retardation and suicidality) are not used (Table 3.4).
TABLE 3.4 MNEMONIC FOR DYSTHYMIC EPISODE | |
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For dysthymia, the child or adolescent shows depressed mood or irritability for most of the day, more days than not, and for 1 year at least. In addition, the young person ought to have at least two of the symptoms in Table 3.4. It is also required not to have been without depressive symptoms for >2 months at a time and not to have had a major depressive episode during that year. The following is a case vignette of dysthymic disorder in an adolescent:
David is a 15-year-old boy in grade 9. He lives with his parents and younger sister. David has been failing school over the past year. He exhibits much anger at school and at home most days of the week. He often becomes angry at school because he does not want to deal with people, and he has received multiple in-school suspensions. He feels “crummy” about himself and that he is not getting enough credit for the effort he is putting to complete his schoolwork. He is not able to concentrate, and this frustrates him even further as he claims he tries to complete the work. He has difficulty falling asleep and is fatigued throughout the day. He denies suicidal ideation, feelings of guilt or hopelessness, reports good appetite, and still enjoys hanging out with his friends and playing his guitar. Besides school, his other problem is his relationship with his father, who tells David what to do, is very short and punitive, especially about school problems.
DEVELOPMENTAL DIFFERENCES IN THE CLINICAL PRESENTATION OF DEPRESSION
Children and adolescents with depression have an overall clinical presentation that is similar to adults; discrepancies can be attributed to age and developmental level.11, 12, 13, 14, 15 Some studies,11, 12, 13, 14 but not all,16 have reported that depressed children have more somatic complaints, psychomotor agitation, anxiety symptoms, behavior problems, ADHD-like symptoms, hallucinations, and depressed affect, whereas adolescents presented with more melancholic symptoms (e.g. anhedonia, guilt, early morning wakening, weight loss), delusions, suicidal behaviors, and substance abuse. The following is a case vignette of a depressed child: