Conduct disorders in childhood and adolescence
Stephen Scott
Introduction
The term conduct disorder refers to a persistent pattern of antisocial behaviour in which the individual repeatedly breaks social rules and carries out aggressive acts which upset other people. It is the commonest psychiatric disorder of childhood across the world, and the commonest reason for referral to child and adolescent mental health services in Western countries. Antisocial behaviour has the highest continuity into adulthood of all measured human traits except intelligence. A high proportion of children and adolescents with conduct disorder grow up to be antisocial adults with impoverished and destructive lifestyles; a significant minority will develop antisocial personality disorder (psychopathy). The disorder in adolescence is becoming more frequent in Western countries and places a large personal and economic burden on individuals and society.
Relation to other disorders
Conduct disorder is one of the two disruptive disorders of childhood, (also known as externalizing disorders); the other is the hyperkinetic syndrome (ICD 10), a more severe form of attention-deficit hyperactivity disorder (ADHD, DSM IV-R). Conduct disorder and the hyperkinetic syndrome are distinct disorders but often co-occur. As discussed in Chapter 9.1.1 on classification, disruptive disorders can be distinguished on a number of criteria from the other main grouping of child psychiatric conditions, the emotional disorders (also known as internalizing disorders). For example, unlike emotional disorders, disruptive disorders are commoner in boys, the socially disadvantaged, children from large families, and where there is parental discord.
Juvenile delinquency is a legal term referring to an act by a young person who has been convicted of an offence which would be deemed a crime if committed by an adult. Most, but not all, recurrent juvenile offenders have conduct disorder. In this chapter the term conduct disorder is used as defined by ICD 10 diagnostic criteria; the term conduct problems will be used for less severe antisocial behaviour.
Social problem or medical diagnosis?
Infringement of the rights of other people is a requirement for the diagnosis of conduct disorder. Since the manifestations include a
failure to obey social rules despite apparently intact mental state and social capacities, many have seen the disorder as principally socially determined. They therefore believe the responsibility for its cause and elimination lies with people who can influence the socialization process, such as parents, schoolteachers, social service departments, and politicians. Due to the impossibility of their seeing all cases, there is some debate within child and adolescent psychiatry as to whether doctors and mental health professionals should be involved in any but the most complex presentations.(1) Some have argued that involvement of medical personnel carries the risk of their becoming agents of social control through the misapplication of diagnostic labels, which may lead to abuses of the kind seen in some totalitarian regimes.
failure to obey social rules despite apparently intact mental state and social capacities, many have seen the disorder as principally socially determined. They therefore believe the responsibility for its cause and elimination lies with people who can influence the socialization process, such as parents, schoolteachers, social service departments, and politicians. Due to the impossibility of their seeing all cases, there is some debate within child and adolescent psychiatry as to whether doctors and mental health professionals should be involved in any but the most complex presentations.(1) Some have argued that involvement of medical personnel carries the risk of their becoming agents of social control through the misapplication of diagnostic labels, which may lead to abuses of the kind seen in some totalitarian regimes.
However, advances in the last decade have shown there are substantial genetic and biological contributions to conduct disorder, and in some cases the symptoms may be responsive to medication. Work in the last 25 years mainly from the field of child and adolescent mental health has clarified many of the mechanisms contributing to the development and persistence of antisocial behaviour, and has led to the development of effective treatments. As yet these are not being widely used with the children and adolescents who need them. Therefore psychiatrists need to be able to contribute to the planning and delivery of an appropriate service.
Clinical features
Aggressive and defiant behaviour is an important part of normal child and adolescent development which ensures physical and social survival. Indeed, parents may express concern if a child is too acquiescent and unassertive. The level of aggressive and defiant behaviour varies considerably amongst children, and it is probably most usefully seen as a continuously distributed trait. Empirical studies do not suggest a level at which symptoms become qualitatively different, nor is there a single cut-off point at which they become impairing for the child or a clear problem for others. There is no hump towards the end of the distribution curve of severity to suggest a categorically distinct group who might on these grounds warrant a diagnosis of conduct disorder.
Picking a particular level of antisocial behaviour to call conduct disorder is therefore necessarily arbitrary. For all children, the expression of any particular behaviour also varies according to child age, so that for example physical hitting is at a maximum at around 2 years of age but declines to a low level over the next few years. Therefore any judgement about the significance of the level of antisocial behaviour has to be made in the context of the child’s age. Before deciding that the behaviour is abnormal or a significant problem, a number of other clinical features have to be considered:
Level: severity and frequency of antisocial acts, compared with children of the same age and gender
Pattern: the variety of antisocial acts, and the setting in which they are carried out
Persistence: duration over time
Impact: distress and social impairment of child; disruption and damage caused to others.
Change in clinical features with age
The type of behaviour seen will depend on the age and gender of the individual.
Younger children, say from 3 to 7 years of age, usually present with general defiance of adults wishes, disobedience of instructions, angry outbursts with temper tantrums, physical aggression to people especially siblings and peers, destruction of property, arguing, blaming others for things that have gone wrong, and a tendency to annoy and provoke others.
In middle childhood, say from 8 to 11, the above features are often present but as the child grows older, stronger, and spends more time out of the home, other behaviours are seen. They include: swearing, lying about what they have been doing, stealing of others belongings outside the home, persistent breaking of rules, physical fights, bullying of other children, cruelty to animals, and setting of fires.
In adolescence, say from 12 to 17, more antisocial behaviours are often added: cruelty and hurting of other people, assault, robbery using force, vandalism, breaking and entering houses, stealing from cars, driving and taking away cars without permission, running away from home, truanting from school, extensive use of narcotic drugs.
Not all children who start with the type of behaviours listed in early childhood progress on to the later, more severe forms. Only about half continue from those in early childhood to those in middle childhood(2); likewise only about a further half of those with the behaviours in middle childhood progress to show the behaviours listed for adolescence. However, the early onset group are important as they are far more likely to display the most severe symptoms in adolescence, and to persist in their antisocial tendencies into adulthood. Indeed over 90 per cent of severe, recurrent adolescent offenders showed marked antisocial behaviour in early childhood. In contrast, there is a large group who only start to be antisocial in adolescence, but whose behaviours are less extreme and who tend to desist by the time they are adults.
Girls
Severe antisocial behaviour is less common in girls who are less likely to be physically aggressive and engage in criminal behaviour, but more likely to show spitefulness, emotional bullying (such as excluding children from groups, spreading rumours so others are rejected by their peers), frequent unprotected sex leading to sexually transmitted diseases and pregnancy, drug abuse, and running away from home.
Pattern and setting
Prognosis is determined by the frequency and intensity of antisocial behaviours, the variety of types, the number of settings in which they occur (e.g. home, school, and in public), and their persistence. For general populations of children, the correlation between parent and teacher ratings on the same measures is only 0.2 to 0.3, so that there are many children who are perceived to be mildly or moderately antisocial at home but well behaved at school, and vice versa. However, for more severe antisocial behaviour, there are usually manifestations both at home and at school.
Impact
At home the child often is subject to high levels of criticism and hostility, and sometimes made a scapegoat for a catalogue of family misfortunes. Frequent punishments and physical abuse are not uncommon. The whole family atmosphere is often soured and siblings also affected. Maternal depression is often present, and families who are unable to cope may, as a last resort, give up the child to be cared for by the local authority. At school, teachers may
take a range of measures to attempt to control the child and protect the other pupils, including sending the child out of the class, sometimes culminating in permanent exclusion from the school. This may lead to reduced opportunity to learn subjects on the curriculum and poor examination results. The child typically has few if any friends, who get fed up with their aggressive behaviour. This often leads to exclusion from many group activities, games, and trips, so restricting the child’s quality of life and experiences. On leaving school the lack of social skills, low level of qualifications, and presence of a police record make it harder to gain employment.
take a range of measures to attempt to control the child and protect the other pupils, including sending the child out of the class, sometimes culminating in permanent exclusion from the school. This may lead to reduced opportunity to learn subjects on the curriculum and poor examination results. The child typically has few if any friends, who get fed up with their aggressive behaviour. This often leads to exclusion from many group activities, games, and trips, so restricting the child’s quality of life and experiences. On leaving school the lack of social skills, low level of qualifications, and presence of a police record make it harder to gain employment.
Classification
The ICD-10 classification has a category for conduct disorders, F91. The Clinical descriptions and diagnostic guidelines(3) state:
Examples of the behaviours on which the diagnosis is based include the following: excessive levels of fighting or bullying; cruelty to animals or other people; severe destructiveness to property; firesetting; stealing; repeated lying; truancy from school and running away from home; unusually frequent and severe temper tantrums; defiant provocative behaviour; and persistent severe disobedience. Any one of these categories, if marked, is sufficient for the diagnosis, but isolated dissocial acts are not. (p. 267)
An enduring pattern of behaviour should be present, but no time frame is given and there is no impairment or impact criterion stated.
The ICD-10 Diagnostic criteria for research(4) differ, requiring symptoms to have been present for at least 6 months, and the introductory rubric indicates that impact upon others (in terms of violation of their basic rights), but not impairment of the child, can contribute to the diagnosis. The research criteria take a menu-driven approach whereby a certain number of symptoms have to be present. 15 behaviours are listed to consider for the diagnosis of Conduct Disorder, which usually but not exclusively apply to older children and teenagers. They can be grouped into four classes:
(a) Aggression to people and animals
often lies or breaks promises to obtain goods or favours or to avoid obligations
frequently initiates physical fights (this does not include fights with siblings)
has used a weapon that can cause serious physical harm to others (e.g. bat, brick, broken bottle, knife, gun)
often stays out after dark despite parenting prohibition (beginning before 13 years of age)
exhibits physical cruelty to other people (e.g. ties up, cuts, or burns a victim), and
exhibits physical cruelty to animals.
(b) Destruction of property
deliberately destroys the property of others (other than by firesetting) and
deliberately sets fires with a risk or intention of causing serious damage).
(c) Deceitfulness or theft
steals objects of non-trivial value without confronting the victim, either within the home or outside (e.g. shoplifting, burglary, forgery).
(d) Serious violations of rules
is frequently truant from school, beginning before 13 years of age
has run away from parental or parental surrogate home at least twice or has run away once for more than a single night (this does not include leaving to avoid physical or sexual abuse)
commits a crime involving confrontation with the victim (including purse-snatching, extortion, mugging)
forces another person into sexual activity
frequently bullies others (e.g. deliberate infliction of pain or hurt, including persistent intimidation, tormenting, or molestation), and
breaks into someone else’s house, building, or car.
To make a diagnosis, three symptoms from this list have to be present, one for at least 6 months. There is no impairment criterion. There are three subtypes: conduct disorder confined to the family context (F91.0), unsocialized conduct disorder (F91.1, where the young person has no friends and is rejected by peers), and socialized conduct disorder (F91.2, where peer relationships are normal). It is recommended that age of onset be specified, with childhood onset type manifesting before age 10, and adolescent onset type after. Severity should be categorized as mild, moderate, or severe according to number of symptoms or impact on others, e.g. causing severe physical injury, vandalism, theft.
For younger children, say up to 9 or 10 years old, there is a list of eight symptoms for the subtype known as Oppositional Defiant Disorder (F91.3):
1 has unusually frequent or severe temper tantrums for his or her developmental level
2 often argues with adults
3 often actively refuses adults’ requests or defies rules
4 often, apparently deliberately, does things that annoy other people
5 often blames others for his or her own mistakes or misbehaviour
6 is often touchy or easily annoyed by others
7 is often angry or resentful
8 is often spiteful or resentful.
To make a diagnosis of the oppositional defiant type of conduct disorder, four symptoms from either this list or the main conduct disorder 15 symptom list have to be present, but no more than two from the latter. Unlike the main variant, there is an impairment criterion: the symptoms must be amaladaptive and inconsistent with the developmental level (p. 161).
Where there are sufficient symptoms of a comorbid disorder to meet diagnostic criteria, the ICD-10 system discourages the application of a second diagnosis, and instead offers a single, combined category. There are two major kinds: mixed disorders of conduct
and emotions, of which Depressive Conduct Disorder (F92.0) is the best researched; and Hyperkinetic Conduct Disorder (F90.1). There is modest evidence to suggest these combined conditions may differ somewhat from their constituent elements.
and emotions, of which Depressive Conduct Disorder (F92.0) is the best researched; and Hyperkinetic Conduct Disorder (F90.1). There is modest evidence to suggest these combined conditions may differ somewhat from their constituent elements.
The DSM IV-R system(5) follows the ICD-10 research criteria very closely and does not have separate clinical guidelines. The same 15 behaviours are given for the diagnosis of conduct disorder 312.8, with almost identical wording. As for ICD-10, three symptoms need to be present for diagnosis. Severity and childhood or adolescent onset are specified in the same way. However, unlike ICD-10, there is no division into socialized/unsocialized, or family context only types, and there is a requirement for the behaviour to cause a clinically significant impairment in social, academic, or social functioning. Comorbidity in DSM IV-R is handled by giving as many separate diagnoses as necessary, rather than by having single, combined categories.
In DSM IV-R, oppositional defiant disorder is classified as a separate disorder on its own, and not as a subtype of conduct disorder. Diagnosis requires four symptoms from a list of eight behaviours which are the same as for ICD-10, but unlike ICD-10, all four have to be from the oppositional list, and none may come from the main conduct disorder list. It is doubtful whether oppositional defiant disorder differs substantially from conduct disorder in older children in any associated characteristics, and the value of designating it as a separate disorder is arguable. In this article, the term conduct disorder will henceforth be used as it is in ICD-10, to refer to all variant including oppositional defiant disorder.
Differential diagnosis
Making a diagnosis of conduct disorder is usually straightforward but comorbid conditions are often missed. The differential diagnosis may include:
1 Hyperkinetic syndrome/Attention-deficit hyperactivity disorder. These are the names given by ICD-10 and DSM IV-R respectively for similar conditions, except that the former is more severe. For convenience the term hyperactivity will be used here. It is characterized by impulsivity, inattention, and motor overactivity. Any of these three sets of symptoms can be misconstrued as antisocial, particularly impulsivity which is also present in conduct disorder. However, none of the symptoms of conduct disorder are a part of hyperactivity so excluding conduct disorder should not be difficult. A frequently made error however, is to miss comorbid hyperactivity when conduct disorder is definitely present. Standardized questionnaires are very helpful here, such as the Strengths and Difficulties Questionnaire, which is brief, and just as effective at detecting hyperactivity as much longer alternatives.(6)
2 Adjustment reaction to an external stressor. This can be diagnosed when onset occurs soon after exposure to an identifiable psychosocial stressor such as divorce, bereavement, trauma, abuse, or adoption. The onset should be within 1 month for ICD-10, and 3 months for DSM IV-R, and symptoms should not persist for more than 6 months after the cessation of the stress or its sequelae.
3 Mood disorders. Depression can present with irritability and oppositional symptoms but unlike typical conduct disorder mood is usually clearly low and there are vegetative features; also more severe conduct problems are absent. Early manic depressive disorder can be harder to distinguish, as there is often considerable defiance and irritability combined with disregard for rules, and behaviour which violates the rights of others. Low self-esteem is the norm in conduct disorder, as is a lack of friends or constructive pastimes. Therefore it is easy to overlook more pronounced depressive symptoms. Systematic surveys reveal that around a third of children with conduct disorder have depressive or other emotional symptoms severe enough to warrant a diagnosis.
4 Autistic spectrum disorders. These are often accompanied by marked tantrums or destructiveness, which may be the reason for seeking a referral. Enquiring about other symptoms of autistic spectrum disorders should reveal their presence.
5 Dissocial/antisocial personality disorder. In ICD-10 it is suggested a person should be 17 or older before dissocial personality is considered. Since at age 18 most diagnoses specific to childhood and adolescence no longer apply, in practice there is seldom difficulty. In DSM IV-R conduct disorder can be diagnosed over 18 so there is potential overlap. A difference in emphasis is the severity and pervasiveness of the symptoms of those with personality disorder, whereby all the individual’s relationships are affected by the behaviour pattern, and the individual’s beliefs about his antisocial behaviour are characterized by callousness and lack of remorse.
6 Subcultural deviance. Some youths are antisocial and commit crimes but are not particularly aggressive or defiant. They are well adjusted within a deviant peer culture that approves of recreational drug use, shoplifting, etc. In some localities a third or more teenage males fit this description and would meet ICD-10 diagnostic guidelines for socialized conduct disorder. Some clinicians are unhappy to label such a large proportion of the population with a psychiatric disorder. Using DSM IV-R criteria would preclude the diagnosis for most youths like this due to the requirement for significant impairment.
Multiaxial assessment
ICD-10 recommends that multiaxial assessment be carried out for children and adolescents, while DSM IV-R suggests it for all ages. In both systems axis one is used for psychiatric disorders which have been discussed above. The last three axes in both systems cover general medical conditions, psychosocial problems, and level of social functioning respectively; these topics will be alluded to below under aetiology. In the middle are two axes in ICD-10, which cover specific (Axis two) and general (Axis three) learning disabilities respectively; and one in DSM IV-R (Axis two) which covers personality disorders and general learning disabilities.
Both specific and general learning disabilities are essential to assess in individuals with conduct problems. Fully a third of children with conduct disorder also have specific reading retardation(7) defined as having a reading level two standard deviations below that predicted by the person’s IQ. While this may in part be due to lack of adequate schooling, there is good evidence that the cognitive deficits often precede the behavioural problems. General learning disability (mental retardation) is often missed in children with conduct disorder unless IQ testing is carried out. The rate of conduct disorder rise several-fold as IQ gets below 70.
Epidemiology
Between 5 per cent and 10 per cent of children and adolescents have significant persistent oppositional, disruptive, or aggressive behaviour problems.(8, 9) With respect to historical period, a modest rise in diagnosable conduct disorder over the second half of the twentieth century has also been observed comparing assessments of three successive birth cohorts in Britain.(10) There is a marked social class gradient.(9) With respect to ethnicity, youth self-reports of antisocial behaviours, and crime victim survey reports of perpetrators’ ethnicity show an excess of offenders of black African ancestry. Importantly, Hispanic Americans in the United States of America and British Asians in the United Kingdom do not tend to show an excess of offending compared to their white counterparts.
Sex differences in prevalence
The sex ratio is approximately 2:5 males for each female overall, with males further exceeding females in the frequency and severity of behaviours. On balance, research suggests that the causes of conduct problems are the same for the sexes, but males have more conduct disorder because they experience more of its individual-level risk factors (e.g. hyperactivity, neurodevelopmental delays). However, recent years have seen increasing concern amongst clinicians about treating antisocial behaviour amongst girls.(11)
Developmental subtypes
Life-course persistent versus adolescence-limited
There has been considerable attention paid to the distinction between conduct problems that are first seen in early childhood versus those that start in adolescence(2) and these two subtypes are encoded in the DSM-IV. Early onset is a strong predictor of persistence through childhood, and early onset delinquency is more likely to persist into adult life. Those with early onset differ from those with later onset in that they have lower IQ, more attentional and impulsivity problems, poorer scores on neuropsychological tests, greater peer difficulties and they are more likely to come from adverse family circumstances.(2) Those with later onset become delinquent predominantly as a result of social influences such as association with other delinquent youths. Findings from the follow-up of the Dunedin cohort support relatively poorer adult outcomes for the early onset group in domains of violence, mental health, substance abuse, work, and family life.(2) However the ‘adolescence-limited’ group were not without adult difficulties. As adults they still engaged in self-reported offending, and they also had problems with alcohol and drugs. Thus, the age-of-onset subtype distinction has strong predictive validity, but adolescent onset antisocial behaviours may have more long-lasting consequences than previously supposed, and so both conduct problems warrant clinical attention.
Aetiology
Individual-level characteristics
(a) Identified genotypes
The search for specific genetic polymorphisms is a very new scientific initiative, and little has yet been accomplished. The moststudied candidate gene in relation to conduct problems is the MAOA promoter polymorphism. The gene encodes the MAOA enzyme, which metabolizes neurotransmitters linked to aggressive behaviour. Replicated studies show that maltreatment history and genotype interact to predict antisocial outcome.(12)
(b) Perinatal complications and temperament
Recent large-scale general population studies have found associations between life-course persistent type conduct problems and perinatal complications, minor physical anomalies, and low birth weight.(13) Most studies support a biosocial model in which obstetric complications might confer vulnerability to other co-ocurring risks such as hostile or inconsistent parenting. Smoking in pregnancy is a statistical risk predictor of offspring conduct problems,(13) but a causal link between smoking and conduct problems has not been established. Several prospective studies have shown associations between irritable temperament and conduct problems.(14)

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