greater postural control and mobility; and (c) situations require changing positions (such as transferring and turning). For example, a patient with Parkinson’s disease (intrinsic factor) may trip over a rug (extrinsic factor) but only under certain situations, such as when walking to the bathroom at night (situational factor). Situational factors are particularly important when an injury results from a fall (37). For example, major injuries are more likely when falling from an upright position (with greater potential energy to be dissipated) and when falling laterally, with direct impact on the hip. Other environmental factors (e.g., hardness of impact surface) and other intrinsic factors (e.g., low femoral bone mineral density and body mass index) also contribute to increased risk of fall-related injury (9,15).
Table 9-1. Intrinsic Factors Contributing to Risk of Falls, Fall-Related Injury, and Gait Disorders | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Table 9-2. Medications Contributing to Risk of Falls, Fall-Related Injury, and Gait Disorders | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
These underlying diseases, both neurologic and nonneurologic, are the major contributors to disordered gait. In a primary care setting, patients consider pain, stiffness, dizziness, numbness, weakness, and sensations of abnormal movement to be the most common contributors to their walking difficulties (17). The most common diagnoses found in a primary care setting thought to contribute to gait disorders include degenerative joint disease, acquired musculoskeletal deformities, intermittent claudication, postorthopedic surgery and poststroke impairments, and postural hypotension (17). Usually, more than one contributing diagnosis is found. Factors such as dementia and fear of falling also contribute to gait disorders. The diagnoses found in a neurologic referral population are primarily neurologically oriented (12, 34): frontal gait disorders [usually related to normal pressure hydrocephalus (NPH) and cerebrovascular processes]; sensory disorders (also involving vestibular and visual function); myelopathy; previously undiagnosed Parkinson’s disease or parkinsonian syndromes; and cerebellar disease. Known conditions causing severe impairment (e.g., hemiplegia and severe hip or knee disease) are frequently not referred to a neurologist. Thus, many gait disorders, particularly those that are classical and discrete (e.g., related to stroke and osteoarthritis) and those that are mild or may relate to irreversible disease (e.g., multi-infarct dementia), are presumably diagnosed in a primary care setting and treated without a referral to a neurologist. Other less common contributors to gait disorders include metabolic disorders (related to renal or hepatic disease), central nervous system (CNS) tumors or subdural hematoma, depression, and psychotropic medications. Case reports also document reversible gait disorders caused by clinically overt hypo- or hyperthyroidism and vitamin B12 and folate deficiency [for detailed review, see Alexander (2)].
Table 9-3. Extrinsic and Situational Factors Contributing to Risk of Falls and Fall-Related Injury | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
|
[reviewed by Alexander (2)]. Some authors have proposed the emergence of an age-related gait disorder without accompanying clinical abnormalities (i.e., essential “senile” gait disorder) (20). This gait pattern is described as broad based with small steps, diminished arm swing, stooped posture, flexion of the hips and knees, uncertainty and stiffness in turning, occasional difficulty initiating steps, and a tendency toward falling. These and other nonspecific findings (e.g., inability to perform tandem gait) are similar to gait patterns found in a number of other diseases, and yet the clinical abnormalities are insufficient to make a specific diagnosis. This “disorder” may be a precursor to an as-yet-asymptomatic disease (e.g., related to subtle extrapyramidal signs) and is likely to be a manifestation of concurrent, progressive cognitive impairment (e.g., Alzheimer’s disease or vascular dementia) (10). Thus, “senile” gait disorder potentially reflects a number of potential disease causes and is generally not useful in labeling gait disorders in older adults.