This chapter presents some algorithms for decision-making, inspired not only by the clinical aspects but also by the organizational, technological, and professional characteristics of the hospital receiving and caring for the acute stroke patients. A summarizing table (decisional algorithm, Table 4.1) classifies the various settings (A, B, C, D) in which clinicians manage patients. These algorithms are to be considered as reference material for helping physicians in selecting the most adequate pathway according to the hospital facilities available.