Double Hemorrhage Model of Experimental Subarachnoid Hemorrhage

 

Day 1 (pre-SAH)

Day 7 (post-SAH)

P value

Physiological parameters

Body weight (kg)

10.3 ± 0.6

9.5 ± 0.6

<0.01

Mean blood pressure (mmHg)

123 ± 18

101 ± 13

<0.01

Heart rate (beats/min)

133 ± 30

92 ± 26

<0.01

Body temperature (°C)

38.3 ± 0.5

38.3 ± 0.4

NS

Hemoglobin (g/dl)

12.7 ± 1.1

11.4 ± 1.1

< 0.01

Hematocrit (%)

38 ± 3

34 ± 3

< 0.01

pH

7.36 ± 0.03

7.37 ± 0.02

NS

PaCO2 (mmHg)

40 ± 3

40 ± 3

NS

PaO2 (mmHg)

395 ± 34

422 ± 33

NS

MR imaging findings

Cerebral infarct

none

none
 
Evans index (%)

20.1 ± 1.4

22.8 ± 2.7

<0.01

Diameter (mm) and [% decrease]

BA

1.04 ± 0.15

0.60 ± 0.14 [42 ± 12]

<0.01

VA

0.97 ± 0.19

0.69 ± 0.18 [29 ± 16]

<0.01

SCA

0.82 ± 0.16

0.49 ± 0.12 [39 ± 19]

<0.01


Data are presented as means ± standard deviations

NS not significant


Nov 8, 2016 | Posted by in NEUROLOGY | Comments Off on Double Hemorrhage Model of Experimental Subarachnoid Hemorrhage

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