14 Drug interactions – 1
| T | F | |
|---|---|---|
| 1. Antacids decrease plasma levels of chlorpromazine. |  |  |
| 2. Caffeine antagonizes the anxiolytic effects of benzodiazepines. |  |  |
| 3. Carbamazepine reduces serum antipsychotic levels. |  |  |
| 4. Cimetidine decreases plasma antidepressant levels. |  |  |
| 5. Alcohol and diazepam interact pharmacokinetically. |  |  |
| 6. Acamprosate interacts with disulfiram. |  |  |
| 7. ACE inhibitors reduce lithium levels. |  |  |
| 8. Aminophylline reduces lithium excretion. |  |  |
| 9. Consuming alcohol whilst taking metronidazole can cause throbbing headache. |  |  |
| 10. Inhalational anaesthetics interact with monoamine oxidase inhibitors (MAOIs). |  |  |
| 11. Smoking increases serum antidepressant levels. |  |  |
| 12. Tricyclic antidepressants (TCAs) interact with antihypertensive drugs. |  |  |
| 13. Alcohol can both decrease and increase the levels of TCAs. |  |  |
| 14. TCAs block the depressant effects of alcohol. |  |  |
| 15. Adrenaline interacts significantly with TCAs. |  |  |
| 16. Barbiturates increase the metabolism of TCAs. |  |  |
| 17. Clozapine and carbamazepine should not be co-prescribed. |  |  |
| 18. Fluoxetine decreases clozapine levels. |  |  |
| 19. Grapefruit juice inhibits cytochrome P450 3A. |  |  |
| 20. Chlorothiazide is less likely to cause lithium toxicity than frusemide. |  |  |
| 21. Reboxetine inhibits cytochrome P450. |  |  |
| 22. SSRIs increase plasma concentrations of carbamazepine. |  |  |
| 23. TCAs enhance the effects of chlorpromazine. |  |  |
| 24. Clonidine may interact significantly with TCAs. |  |  |
| 25. Fluoxetine increases levels of diazepam. |  |  |
