General Principles of Nerve Conduction Studies



General Principles of Nerve Conduction Studies





QUESTIONS



1. If a routine sural nerve sensory study shows an absent potential while the patient has a normal sensory examination of the lateral foot, one should consider:


A. Tarsal tunnel syndrome


B. Amyotrophic lateral sclerosis (ALS)


C. Technical problem


D. Absent sural nerve

View Answer

1. (C ): This is most commonly a technical problem, for example, amplifier turned off, electrode placement, skin impedance, previous sural nerve biopsy, edema, or ankle deformity. One should check the integrity of the circuit before attributing the abnormality to a disease. Amyotrophic lateral sclerosis (ALS) is a motor neuron disease and sensory nerves are usually preserved. Tarsal tunnel syndrome (planter nerve entrapment) would not affect the sural sensory response. (Preston and Shapiro 1998, p. 6)



2. All statements about dorsal root ganglion (DRG) are correct except:


A. It contains the cell bodies of 1 C fibers


B. It consists of bipolar cells with two separate axonal projections


C. The projections of DRG enter the spinal cord on the dorsal side


D. Peripheral projections of the DRG become the sensory fibers in the peripheral nerve

View Answer

2. (A): Dorsal root ganglion contains the cell bodies of large myelinated sensory 1A fibers. It consists of bipolar cells with two separate axonal projections. The projections of dorsal root ganglion enter the spinal cord at the entry zone of the dorsal funiculus. Peripheral projections of the DRG eventually become the sensory fibers in the peripheral nerve. (Preston and Shapiro 1998, p. 9)



3. The following statements about myelination are correct except:


A. Myelin is present on all sensory conducting fibers


B. Myelin is derived from Schwann cells, the major supporting cells in the peripheral nervous system


C. For every myelinated fiber, successive segments are myelinated by single Schwann cell


D. The axonal member is exposed near the neuromuscular junction

View Answer

3. (A): Only large fast conducting fibers are myelinated. Myelination of the peripheral nerves is the function of the Schwann cells and every segment is myelinated by a single Schwann cell. The myelination is absent near the neuromuscular junction and at nodes of Ranvier. (Preston and Shapiro 1998, p. 12)




4. All statements are correct except:


A. Amplitude is usually measured from baseline to the negative peak


B. Controlled motor action potential (CMAP) duration is a measure of synchrony (simultaneous firing of individual muscle fibers)


C. Conduction velocity is a measure of the speed of the fastest conducting motor axons


D. When the nerve is stimulated proximally, the CMAP amplitude is approximately half the amplitude of the distal stimulation waveform

View Answer

4. (D): When the nerve is stimulated proximally the CMAP area, amplitude, and duration are similar to those of the distal stimulation waveform. CMAP amplitude is usually measured from baseline to the negative peak and less commonly from the first negative peak to the next positive peak. CMAP duration is a measure of synchrony (simultaneous firing of individual muscle fibers). Conduction velocity is a measure of the speed of the fastest conducting motor axons, which is calculated by dividing the distance traveled by the nerve conduction time from a proximal to a distal stimulation site. One cannot calculate a true distal motor conduction velocity by using a distal motor latency and a distance; as the velocity measurement would include the conduction time through the neuromuscular junction and along the muscle fiber. (Preston and Shapiro 1998, p. 26)



5. Cool temperatures of the limb result in a change in nerve conduction study as:


A. Increase in conduction velocity


B. Decrease in conduction velocity


C. Decrease in F-wave latency


D. Decrease in amplitude

View Answer

5. (B): Cool temperatures result in slowing of conduction velocity, which is prominent in large rather than small myelinated fibers. For motor and sensory studies, conduction velocity slows between 1.5 and 2.5 m per second for every 1C drop in temperature and distal latency prolongs by approximately 0.2 ms per degree. Cooling of the limb results in a larger amplitude and longer duration potential, associated with a longer distal latency and slower conduction velocity. (Preston and Shapiro 1998, p. 85)



6. The following maneuvers will help decrease the stimulus artifact except:


A. Ground electrode should not be placed between the stimulator and the recording electrodes


B. Reducing electrodes impedance mismatch


C. Rotate the anode of the stimulator while maintaining the position of the cathode


D. Stimulator and recording electrode cables do not overlap

View Answer

6. (A): Placing ground electrode between the stimulator and the recording electrodes helps reduce the stimulus artifact. Reducing electrodes impedance will decrease the stimulus. Rotating the anode of the stimulator while maintaining the position of the cathode will decrease the stimulus. Keeping the stimulator and recording electrode cables separate and kept as far as possible will help reduce the influence of stimulus artifact. (Preston and Shapiro 1998, p. 90)

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Aug 28, 2016 | Posted by in NEUROLOGY | Comments Off on General Principles of Nerve Conduction Studies

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