Chapter 5 Guillain–Barré syndrome DEFINITION Acute inflammatory demyelinating polyneuropathy (AIDP) Acute motor axonal neuropathy (AMAN) Chronic inflammatory demyelinating polyneuropathy (CIDP) EPIDEMIOLOGY Prevalence Age Gender AETIOLOGY PATHOLOGY Demyelination Axonal loss OUTCOME AND PROGNOSIS SIGNS AND SYMPTOMS Motor Sensory Autonomic dysfunction Secondary complications Definition Guillain–Barré syndrome (GBS) is included in the wider group of peripheral polyneuropathies and is an autoimmune disease affecting the peripheral nervous system (PNS) characterized by a rapid demyelination, followed by remyelination. There are several types of GBS. Acute inflammatory demyelinating polyneuropathy (AIDP) This is the most common form. Acute motor axonal neuropathy (AMAN) Also termed acute motor and sensory axonal neuropathy (AMSAN). Chronic inflammatory demyelinating polyneuropathy (CIDP) As the name suggests, this involves a more chronic onset than other forms of GBS. Typically, patients with CIDP have a chronic progressive or relapsing remitting illness developing over at least 2 months but then potentially continuing for many years. Epidemiology Prevalence GBS affects about one person in 40 000 each year in the UK. Age It can occur at any age from infancy onwards but is slightly more common in the elderly. Gender It is more common in men than in women. Aetiology The definitive cause of GBS is uncertain, however in many cases there appears to be a prior infection, e.g. glandular fever or campylobacter. Recent surgery is also recognized as a triggering event. Pathology Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: Motor neuron disease Introduction to excitable tissue Meninges, ventricular system and blood supply Myotomes Postural alignment Strength Stay updated, free articles. Join our Telegram channel Join Tags: Neurological Assessment A Clinicians Guide Jun 4, 2016 | Posted by admin in NEUROLOGY | Comments Off on Guillain–Barré syndrome Full access? Get Clinical Tree
Chapter 5 Guillain–Barré syndrome DEFINITION Acute inflammatory demyelinating polyneuropathy (AIDP) Acute motor axonal neuropathy (AMAN) Chronic inflammatory demyelinating polyneuropathy (CIDP) EPIDEMIOLOGY Prevalence Age Gender AETIOLOGY PATHOLOGY Demyelination Axonal loss OUTCOME AND PROGNOSIS SIGNS AND SYMPTOMS Motor Sensory Autonomic dysfunction Secondary complications Definition Guillain–Barré syndrome (GBS) is included in the wider group of peripheral polyneuropathies and is an autoimmune disease affecting the peripheral nervous system (PNS) characterized by a rapid demyelination, followed by remyelination. There are several types of GBS. Acute inflammatory demyelinating polyneuropathy (AIDP) This is the most common form. Acute motor axonal neuropathy (AMAN) Also termed acute motor and sensory axonal neuropathy (AMSAN). Chronic inflammatory demyelinating polyneuropathy (CIDP) As the name suggests, this involves a more chronic onset than other forms of GBS. Typically, patients with CIDP have a chronic progressive or relapsing remitting illness developing over at least 2 months but then potentially continuing for many years. Epidemiology Prevalence GBS affects about one person in 40 000 each year in the UK. Age It can occur at any age from infancy onwards but is slightly more common in the elderly. Gender It is more common in men than in women. Aetiology The definitive cause of GBS is uncertain, however in many cases there appears to be a prior infection, e.g. glandular fever or campylobacter. Recent surgery is also recognized as a triggering event. Pathology Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: Motor neuron disease Introduction to excitable tissue Meninges, ventricular system and blood supply Myotomes Postural alignment Strength Stay updated, free articles. Join our Telegram channel Join Tags: Neurological Assessment A Clinicians Guide Jun 4, 2016 | Posted by admin in NEUROLOGY | Comments Off on Guillain–Barré syndrome Full access? Get Clinical Tree
