Hyperdense CSF

Hyperdense CSF
Bronwyn E. Hamilton, MD
DIFFERENTIAL DIAGNOSIS
Common
  • Subarachnoid Hemorrhage (SAH), Traumatic
  • Aneurysmal Subarachnoid Hemorrhage
  • Streak Artifact
  • Diffuse Cerebral Edema (Mimic)
  • Brain Death (Mimic)
Less Common
  • Contrast Material
  • Chronic Renal Failure
  • Ventriculitis
  • Meningitis
  • Metastases, Meningeal
Rare but Important
  • Nonaneurysmal Perimesencephalic SAH
  • Superficial Siderosis
ESSENTIAL INFORMATION
Helpful Clues for Common Diagnoses
  • Subarachnoid Hemorrhage, Traumatic
    • Peripheral sulci, interpeduncular cistern
    • Less extensive than aneurysmal blood
  • Aneurysmal Subarachnoid Hemorrhage
    • Typically basal cisterns, may be diffuse
    • Location may indicate causative aneurysm
  • Streak Artifact
    • Non-anatomical distribution
    • Due to metal & dense bone interfaces
  • Diffuse Cerebral Edema (Mimic)
    • Diffuse low density in supratentorial brain causes “pseudo SAH”
    • Gyri swollen, cisterns compressed
    • “Cerebellar reversal sign”: Density of cerebellum > > hemispheres
  • Brain Death (Mimic)
    • Diffuse low density in supratentorial brain causes “pseudo SAH”
    • Gyri swollen, cisterns compressed
    • “Cerebellar reversal sign”: Density of cerebellum > > hemispheres
    • Clinical criteria for confirmation
Helpful Clues for Less Common Diagnoses
  • Contrast Material
    • Noncontrast CT follows recent contrast procedure (myelogram, cisternogram)
  • Chronic Renal Failure
    • Causes contrast recirculation from recent IV contrast injection
  • Ventriculitis
    • Ventriculomegaly with debris level, enhancing ependyma
  • Meningitis
    • Normal CT or mild ventriculomegaly
    • May see hyperdense CSF, especially in fungal infections & TB
  • Metastases, Meningeal
    • May see hyperdense CSF, effaced sulci
Helpful Clues for Rare Diagnoses
  • Nonaneurysmal Perimesencephalic SAH
    • Small volume hemorrhage in basal cisterns
  • Superficial Siderosis
    • Atrophy; hyperdensity along brain surface
Aug 7, 2016 | Posted by in NEUROLOGY | Comments Off on Hyperdense CSF

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