Hyperdense CSF
Bronwyn E. Hamilton, MD
DIFFERENTIAL DIAGNOSIS
Common
Subarachnoid Hemorrhage (SAH), Traumatic
Aneurysmal Subarachnoid Hemorrhage
Streak Artifact
Diffuse Cerebral Edema (Mimic)
Brain Death (Mimic)
Less Common
Contrast Material
Chronic Renal Failure
Ventriculitis
Meningitis
Metastases, Meningeal
Rare but Important
Nonaneurysmal Perimesencephalic SAH
Superficial Siderosis
ESSENTIAL INFORMATION
Helpful Clues for Common Diagnoses
Subarachnoid Hemorrhage, Traumatic
Peripheral sulci, interpeduncular cistern
Less extensive than aneurysmal blood
Aneurysmal Subarachnoid Hemorrhage
Typically basal cisterns, may be diffuse
Location may indicate causative aneurysm
Streak Artifact
Non-anatomical distribution
Due to metal & dense bone interfaces
Diffuse Cerebral Edema (Mimic)
Diffuse low density in supratentorial brain causes “pseudo SAH”
Gyri swollen, cisterns compressed
“Cerebellar reversal sign”: Density of cerebellum > > hemispheres
Brain Death (Mimic)
Diffuse low density in supratentorial brain causes “pseudo SAH”
Gyri swollen, cisterns compressed
“Cerebellar reversal sign”: Density of cerebellum > > hemispheres
Clinical criteria for confirmation
Helpful Clues for Less Common Diagnoses
Contrast Material
Noncontrast CT follows recent contrast procedure (myelogram, cisternogram)
Chronic Renal Failure
Causes contrast recirculation from recent IV contrast injection
Ventriculitis
Ventriculomegaly with debris level, enhancing ependyma
Meningitis
Normal CT or mild ventriculomegaly
May see hyperdense CSF, especially in fungal infections & TB
Metastases, Meningeal
May see hyperdense CSF, effaced sulci
Helpful Clues for Rare Diagnoses
Nonaneurysmal Perimesencephalic SAH
Small volume hemorrhage in basal cisterns
Superficial Siderosis
Atrophy; hyperdensity along brain surface
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