Hyperdense CSF
Bronwyn E. Hamilton, MD
DIFFERENTIAL DIAGNOSIS
Common
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Subarachnoid Hemorrhage (SAH), Traumatic
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Aneurysmal Subarachnoid Hemorrhage
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Streak Artifact
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Diffuse Cerebral Edema (Mimic)
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Brain Death (Mimic)
Less Common
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Contrast Material
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Chronic Renal Failure
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Ventriculitis
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Meningitis
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Metastases, Meningeal
Rare but Important
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Nonaneurysmal Perimesencephalic SAH
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Superficial Siderosis
ESSENTIAL INFORMATION
Helpful Clues for Common Diagnoses
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Subarachnoid Hemorrhage, Traumatic
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Peripheral sulci, interpeduncular cistern
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Less extensive than aneurysmal blood
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Aneurysmal Subarachnoid Hemorrhage
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Typically basal cisterns, may be diffuse
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Location may indicate causative aneurysm
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Streak Artifact
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Non-anatomical distribution
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Due to metal & dense bone interfaces
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Diffuse Cerebral Edema (Mimic)
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Diffuse low density in supratentorial brain causes “pseudo SAH”
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Gyri swollen, cisterns compressed
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“Cerebellar reversal sign”: Density of cerebellum > > hemispheres
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Brain Death (Mimic)
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Diffuse low density in supratentorial brain causes “pseudo SAH”
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Gyri swollen, cisterns compressed
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“Cerebellar reversal sign”: Density of cerebellum > > hemispheres
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Clinical criteria for confirmation
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Helpful Clues for Less Common Diagnoses
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Contrast Material
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Noncontrast CT follows recent contrast procedure (myelogram, cisternogram)
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Chronic Renal Failure
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Causes contrast recirculation from recent IV contrast injection
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Ventriculitis
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Ventriculomegaly with debris level, enhancing ependyma
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Meningitis
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Normal CT or mild ventriculomegaly
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May see hyperdense CSF, especially in fungal infections & TB
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Metastases, Meningeal
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May see hyperdense CSF, effaced sulci
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Helpful Clues for Rare Diagnoses
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Nonaneurysmal Perimesencephalic SAH
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Small volume hemorrhage in basal cisterns
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Superficial Siderosis
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Atrophy; hyperdensity along brain surface
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Image Gallery

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