Fig. 27.1
Treatment planning of a left sessile HH extending into the interpeduncular cystern near the optic chiasm. This case was treated with frameless image-guided robotic radiosurgery (Cyberknife) delivering 151 beams carrying a total dose of 16 Gy prescribed to the 70 % isodose (Maximum dose: 22.85 Gy)
In conclusion, HH are brain tumors causing a severe epileptic disorder. Conventional surgical resection is an effective treatment for epilepsy and mass effect but carries a high risk of major neurological deficits and complications. SRS provides an efficacious and low-risk non invasive treatment option for small to medium size HH and for post-surgical residuals.
References
Craig DW, Itty A, Panganiban C, Szelinger S, Krurer MC, Sekar A, Reiman D, Navarayan V, Stephan DA, Kerrigan JF (2008) Identification of somatic chromosomal abnormalities in hypothalamic hamartoma tissue at the GLI3 locus. Am J Hum Genet 82(10):366–374PubMedCentralPubMedCrossRef
Polkey CE (2003) Resective surgery for hypothalamic hamartoma. Epileptic Disord 5(4):281–286PubMed

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