Impairment in Aneurysmal Subarachnoid Hemorrhage Patients with Delayed Cerebral Infarction: Prevalence and Pattern

 

Patients assessed
 
(n = 120)

Age, median (IQR)

51 years (46–61 years)

Women

82 patients (68 %)

Hypertension

41 patients (34 %)

Smoker

31 patients (26 %)

WFNS grade

I

73 patients (61 %)

II

29 patients (24 %)

III

3 patients (2 %)

IV

11 patients (9 %)

V

4 patients (3 %)

Location of aneurysm

Anterior cerebral artery

31 patients (26 %)

PComA

18 patients (15 %)

ICA other than PComA

23 patients (26 %)

Middle cerebral artery

31 patients (26 %)

Posterior circulation

16 patients (13 %)

Aneurysm treatment

Coiling

59 patients (49 %)

Clipping

56 patients (47 %)

Delayed cerebral infarction

19 patients (16 %)

mRS

0

36 patients (30 %)

1

21 patients (18 %)

2

48 patients (40 %)

3

13 patients (11 %)

4

1 patients (1 %)

5

1 patients (1 %)


IQR interquartile ranges, PComA posterior communicating artery, ICA internal carotid artery, WFNS World Federation of Neurosurgical Societies, mRS modified Rankin Scale



One or more cognitive domain deficits were found in 6 (32 %) patients with delayed cerebral infarction and 23 (23 %) patients without delayed cerebral infarction (odds ratio: 1.57, 0.54–4.58, p = 0.290). Cognitive impairment (two or more domain deficits) was found in 4(21 %) patients with delayed cerebral infarction and 11(11 %) patients without delayed cerebral infarction (odds ratio: 2.18, 0.61–7.76, p = 0.192). Cognitive domain deficits commonly affected in aSAH patients with delayed cerebral infarction were verbal memory (21 % vs 4 %; odds ratio: 6.47, 1.45–28.66, p = 0.021), language (16 % vs 6 %; odds ratio: 2.97, 0.67–13.09, p = 0.152), and visuospatial memory and skill (13 % vs 5 %; odds ratio: 2.42, 0.75–7.83, p = 0.126) domains (Table 2).


Table 2
Cognitive domain deficit in patients with and without delayed cerebral infarction (DCI)





































 
Patients with DCI (%) (n = 19)

Patients with no DCI (%) (n = 101)

Odds ratio (95 % CI)

p-value

Verbal memory domain deficit

4 (21)

4 (4)

6.47 (1.45–28.66)

0.021*

Visuospatial skill and memory domain deficit

5 (26)

13 (13)

2.42 (0.75–7.83)

0.126

Attention and working memory domain deficit

2 (10)

6 (6)

1.86 (0.35–10.01)

0.371

Language domain deficit

3 (16)

6 (6)

Only gold members can continue reading. Log In or Register to continue

Stay updated, free articles. Join our Telegram channel

Nov 8, 2016 | Posted by in NEUROLOGY | Comments Off on Impairment in Aneurysmal Subarachnoid Hemorrhage Patients with Delayed Cerebral Infarction: Prevalence and Pattern

Full access? Get Clinical Tree

Get Clinical Tree app for offline access