Infarction After Aneurysmal Subarachnoid Hemorrhage


Characteristics

Presence (n = 162)

Absence (n = 417)

p Value

Age, y

60.6 ± 13.1

61.6 ± 13.9

nsa

Sex
  
nsb

 Female

110 (67.9 %)

284 (68.1 %)
 
 Male

52 (32.1)

133 (31.9)
 
Pre-SAH morbidity
  
nsb

 mRS 0-1

156 (96.3)

395 (94.7)
 
 mRS 2-4

6 (3.7)

22 (5.3)
 
WFNS grade
   
 I

40 (24.7)

129 (30.9)

nsb

 II

37 (22.8)

120 (28.8)

nsb

 III

18 (11.1)

41 (9.8)

nsb

 IV

43 (26.5)

80 (19.2)

nsb

 V

24 (14.8)

47 (11.3)

nsb

Fisher CT group
   
 1

0 (0)

7 (1.7)

nsc

 2

23 (14.2)

94 (22.5)

<0.05b

 3

122 (75.3)

251 (60.2)

<0.001b

 4

17 (10.5)

65 (15.6)

nsb

Aneurysm dome, mm

6.6 ± 3.8

6.4 ± 3.4

nsa

     neck, mm

3.5 ± 1.7

3.4 ± 1.5

nsa

Aneurysm classification
   
 Small size/small neck

77 (47.5)

212 (50.8)

nsb

 Small size/wide neck

57 (35.2)

151 (36.2)

nsb

 Large

28 (17.3)

52 (12.5)

nsb

 Giant

0 (0)

1 (0.2)

nsc

Aneurysm location
   
 Internal carotid artery

42 (25.9)

133 (31.9)

nsb

 Middle cerebral artery

41 (25.3)

90 (21.6)

nsb

 Anterior communicating artery

47 (29.0)

115 (27.6)

nsb

 Distal anterior cerebral artery

5 (3.1)

23 (5.5)

nsc

 Posterior circulation

25 (15.4)

52 (12.5)

nsb

 Other

2 (1.2)

4 (1.0)

nsc

Date of aneurysm obliteration
  
nsb

 Days 0–3

152 (93.8)

385 (92.3)
 
 Days 4–12

10 (6.2)

32 (7.7)
 
Treatment modality
  
nsb

 Clip

89 (54.9)

193 (46.3)
 
 Coil

73 (45.1)

224 (53.7)
 
Pretreatment re-rupture

15 (9.3)

28 (6.7)

nsb

Intratreatment re-rupture: Clip

26 (16.0)

36 (8.6)

<0.025b

           Coil

5 (3.1)

15 (3.6)

nsc

Post-treatment re-rupture

2 (1.2)

10 (2.4)

nsc

Cerebrospinal fluid drainage

119 (73.5)

263 (63.1)

<0.025b

Antiplatelet therapy

38 (23.5)

104 (24.9)

nsb

Symptomatic vasospasm

103 (63.6)

23 (5.5)

<0.001b

Endovascular treatment for vasospasm

48 (29.6)

17 (4.1)

<0.001b

Infection

19 (11.7)

31 (7.4)

nsb

Noninfectious cardiopulmonary complication

8 (4.9)

29 (7.0)

nsc

Epilepsy

7 (4.3)

21 (5.0)

nsc

Shunt-dependent hydrocephalus

43 (26.5)

68 (16.3)

<0.005b


Data, mean ± standard deviation; number of cases (%)

CT computed tomography, mRS modified Rankin Scale, WFNS World Federation of Neurosurgical Societies; day 0 refers to the calendar day of SAH onset, ns not significant

aunpaired t-test

bchi-square test

cFisher’s exact test


Oct 22, 2016 | Posted by in NEUROSURGERY | Comments Off on Infarction After Aneurysmal Subarachnoid Hemorrhage

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