Planning and positioning
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The initial assessment of a patient with a suspected intradural nerve sheath tumor begins with a detailed history and physical examination.
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Magnetic resonance imaging (MRI) with gadolinium contrast agent for lesion localization is essential for planning the surgical approach. Schwannomas are characteristically isointense or hypointense to the spinal cord on T1-weighted images, with cystic areas represented by high T2 signal. Areas of hemorrhage or collagen are seen as low attenuation on T2 sequences. Schwannomas and neurofibromas enhance intensely in a homogeneous or heterogeneous pattern. Patients with neurofibromatosis may have multiple lesions along the entire spinal cord.
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X-rays may show enlargement of neural foramina, a classic finding associated with these lesions, and associated skeletal deformities.
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Intraoperative neurophysiologic monitoring with motor evoked potentials (MEPs) is essential when operating on intradural nerve sheath tumors. The anesthetic regimen should be coordinated with the anesthesiologist before the start of the case because many anesthetic agents cause depression of MEPs. Commonly used agents that do not cause a decline in motor potentials include propofol, fentanyl, and etomidate.