Learning disability – 4

25 Learning disability – 4

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1. Less than half of those with learning disability (LD) have mild LD.
2. Birth injuries account for over 40% of mental retardation.
3. Angelman syndrome is associated with a cheerful disposition.
4. Patients with Asperger syndrome have a narrower repertoire of emotional facial expression.
5. Di George syndrome is caused by a deletion on chromosome 21q11.
6. Down’s syndrome is associated with grand mal seizures.
7. The overall prevalence of mental disorders is lower in Down’s syndrome than in the general population.
8. Children with Down’s syndrome are very capable at mimicry.
9. Up to half of the people with Down’s syndrome have pathology affecting heart valves.
10. Fragile X syndrome is caused by a CAG repeat on the X chromosome.
11. Cryptorchidism is common in Fragile X syndrome.
12. Dietary alteration can reduce the incidence of low IQ in Hartnup disease.
13. In patients with Hurler’s syndrome, survival into the 20s is common.
14. Klein–Levin syndrome is associated with hypersexuality.
15. Infants with Lesch–Nyhan syndrome have hypertonia.
16. Phenylketonuria occurs in 1 in 20 000 live births.
17. Most cases of Prader–Willi syndrome are caused by a chromosome _15 deletion of paternal origin.
18. In Rett syndrome the IQ is usually less than 35.
19. Patients with Trisomy 13 and Trisomy 18 usually survive to adulthood.
20. Tuberous sclerosis complex is associated with seizures.
21. Wilson’s disease is caused by defective absorption of copper.
22. Psychiatric morbidity is higher in those with LD than in the general population.
23. Obsessive compulsive disorder is less frequent in those with LD than in the general population.
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