Indications
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We prefer surgical clipping of most ruptured and unruptured middle cerebral artery (MCA) aneurysms because of the accessibility of their location and the relatively low morbidity and durability of clipping compared with endovascular therapy. The exception is in patients in poor neurologic condition (Hunt and Hess grade III, IV, or V); for these patients, we generally prefer endovascular treatment if feasible.
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The decision to treat an unruptured MCA aneurysm is based on an understanding of the natural history and must be weighed against the risk of surgical intervention. Factors that must be considered include the patient’s age, general health, clinical presentation (headaches, seizures), smoking history, family history of subarachnoid hemorrhage, and aneurysm size.
Planning and positioning
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Preoperative evaluation includes assessment of the patient’s cardiopulmonary status, laboratory values (complete blood count, basic metabolic profile, coagulation profile), chest x-ray, and electrocardiogram. The aneurysm configuration and associated vascular anatomy are defined by digital subtraction angiography with or without three-dimensional reconstruction, computed tomography angiography, or magnetic resonance angiography.
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The patient is given a dose of preoperative antibiotics before skin incision. Brain relaxation is achieved with intravenous mannitol and mild hyperventilation.