Neuroanesthesia
 General Information
1. Provide general information on neuroanesthesia.  | 
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a. Name the most potent cerebral vaso dilator.  | CO2  | G7 p.1:85mm  | 
b. Effect of hyperventilation on  | 
  | G7 p.1:85mm  | 
i. PaCO2  | reduces  | 
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ii. CBV  | decreases  | 
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iii. CBF  | decreases  | 
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iv. Goal is end tidal CO2 of (ETCO2) _____  | 25 to 30 mm Hg  | 
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v. Correlates with a PCO2 of _____  | 30 to 35 mm Hg  | 
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c. For every_____ degree change in temperature  | 1  | G7 p.1:110mm  | 
d. there is a change in cerebral metabolic rate of oxygen by_____%.  | 7%  | 
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e. The effect that hyperglycemia has on ischemic deficits is to make them _____.  | worse  | G7 p.1:115mm  | 
f. Elevating the patient’s head will have the following effect on:  | 
  | G7 p.1:127mm  | 
i. arterial blood flow  | decreases  | 
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ii. ICP  | reduces  | 
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iii. venous blood outflow  | improves  | 
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 Drugs Used in Neuroanesthesia
2. Inhalation anesthesia agents have the following effects:  | 
  | G7 p.1:177mm  | 
a. cerebral vessels_____  | dilate  | 
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b. auto-regulation is_____  | disturbed  | 
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c. cerebral blood volume is_____  | increased  | 
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d. CSF volume is_____  | increased  | 
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e. Reactivity of vessels to CO2 is_____  | increased  | 
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3. What anesthetic drug may come out of solution and aggravate pneumocephalus?  | nitrous oxide  | G7 p.2:45mm  | 
4. To reduce the risk of tension pneumocephalus you would  | 
  | G7 p.2:52mm  | 
a. fill any space with_____  | fluid  | 
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b. and turn off_____  | agent  | 
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c. _____ minutes before closing the dura.  | 10  | 
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5. Complete the following regarding barbiturates:  | 
  | G7 p.2:147mm  | 
a. Most are anticonvulsants but there is an exception that actually lowers the seizure threshold called B_____.  | Brevital  | 
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b. They cause peripheral vaso_____  | dilatation  | 
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c. which may cause_____  | hypotension  | 
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d. and_____ the CPP.  | reduce  | 
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6. True or False. Morphine and Demoral  | 
  | G7 p.3:42mm  | 
a. release histamine  | true  | 
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b. produce hypotension  | true  | 
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c. cause vasodilation  | true  | 
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d. increase ICP  | true  | 
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e. compromise CPP  | true  | 
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f. Demoral can cause seizures.  | true  | 
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7. Characterize synthetic narcotics.  | 
  | G7 p.3:72mm  | 
a. Have the advantage that they don’t cause h_____ r_____.  | histamine release  | 
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b. An example is f_____.  | fentanyl  | G7 p.3:85mm  | 
8. Benzodiazepines are_____agonists.  | GABA  | G7 p.3:115mm  | 
9. Characterize pancuronium (Pavulon).  | 
  | G7 p.4:40mm  | 
a. Potentially,_____ minutes are necessary for full reversal of pancuronium (Pavulon).  | 20  | 
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b. True or false. Due to its long action it is indicated for intubation.  | false  | 
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10. Answer the following questions concerning anesthesia requirements for evoked potential monitoring:  | 
  | G7 p.4:177mm  | 
a. What technique is preferred?  | total IV anesthesia  | 
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b. Second best is_____.  | nitrous/narcotic  | 
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c. Are muscle relaxants permitted?  | yes  | 
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d. How should fentanyl be infused?  | continuously as opposed to intermittent injections  | 
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11. The antiepileptic drugs that do not effect SSEP are  | 
  | G7 p.5:25mm  | 
a. c_____  | carbamazepine  | 
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b. p_____  | phenytoin  | 
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c. p_____  | phenobarbital  | 
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