Neuroimaging



Neuroimaging





Neuroimaging


I. Computed Tomography Density



































Moiety


Hounsfeld Units


Bone


1,000 (more dense)


Calcium


100


Acute blood


85


Tumor


Possibly 30-60


Gray matter


35-40


White matter


25-30


CSF


0


Adipose


-100


Air


-1,000 (less dense)


CSF, cerebrospinal fluid.



II. Computed Tomography in Stroke























Duration


Without Contrast


With Contrast


Hyperacute


Normal or blurring of grey-white junction


No enhancement


Acute


Poorly defined hypodensity, maximal edema


No enhancement or mild gyral enhancement


Subacute


Hypodensity, less edema


Gyral enhancement


Remote


Sharply defined hypodensity


Enhancement in 6 weeks



III. Computed Tomography in Hemorrhage















Duration


Without Contrast


Acute


Hyperdensity, mass effect


Subacute


Hypodense periphery with hyperdense center, mass effect


Remote


Hypodense




IV. High Precontrast Computed Tomography Density with Intense Contrast Enhancement



  • Meningioma


  • Aneurysm


  • Pituitary adenoma


  • Germinoma


  • Medullablastoma


  • Central nervous system lymphoma


  • Acoustic schwannoma


  • Craniopharyngioma


  • Colloid cyst


V. Magnetic Resonance Imaging



  • Repetition time—time between successive radio frequency (RF) pulses


  • Echo time—time between giving the RF pulse and measuring the tissue’s RF signal


  • Relaxation time—time required to return to equilibrium after an RF pulse


  • Magnetic resonance imaging (MRI) is based primarily on the relaxation times of various tissues.


  • Diffusion-weighted images are positive in >90% of ischemic strokes within minutes of the event.


  • Diffusion perfusion images can be obtained to show the mismatch between the images (ischemic and hypoperfused regions). Diffusion-weighted images with stroke detected decreased water mobility. Diffusion-weighted images change within 5 minutes following a stroke. Diffusion-weighted images—2 weeks to change from bright to dark following a stroke. When perfusion defect equals diffusion defect (no mismatch), there is no significant risk for stroke enlargement with a matched defect.


  • Apparent diffusion coefficient map—1 week for change from dark to white following stroke. Apparent diffusion coefficient is the extent of movement of water molecules. With a stroke, cellular water has decreased ability to move.


VI. T1-Weighted Imaging









































Dark (long T1)


Bright (short T1)


Intracellular deoxyhemoglobin


Fat


Calcium


Contrast


Air


Methemoglobin


Water (edema)


Proteinaceous material


Most tumors


Hypoxic changes


Infarction


Melanoma


Demyelinating disease


Hepatic failure


Abscess


Slow-flowing blood


Chronic hemorrhage


Laminar necrosis


CSF


Hepatic failure


Calcification



CSF, cerebrospinal fluid

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Sep 8, 2016 | Posted by in NEUROLOGY | Comments Off on Neuroimaging

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