Neuropsychiatry and Behavioral Neurology
Psychiatry discontinued the term “organic” from the official nomenclature a couple of decades ago, but its significance is still relevant today because the care of patients with identifiable, acquired brain disease (such as epilepsy, movement disorders, and traumatic brain injury) requires the physician to have expertise, knowledge base, and a familiarity with assessment and treatment methods not usually required for patients with primary psychiatric disorders. Patients with organic psychiatric syndromes are common in clinical practice and are often difficult to manage for most general psychiatrists, even with consultation from other specialists who may themselves not be experts in the mental and emotional phenomena, which often accompany brain disease.
Neuropsychiatry is the psychiatric subspecialty that deals with the psychological and behavioral manifestations of brain disorders. Neuropsychiatry is, therefore, closely allied with cognitive and behavioral neurology–that is, the neurological specialty that focuses on psychological phenomena present in patients with brain disorders. In many ways, neuropsychiatry can offer a distinctive perspective on idiopathic psychiatric disorders; its limitations in this respect must also be noted. The limitations include consideration of the multifactorial nature of many psychiatric diseases–namely, interaction between environmental and genetic factors. To date, no psychiatric disorder has been completely mapped. The unraveling of a biological basis for many psychiatric diseases is a novel aspect of the field, which is in its inception phase.
Helpful Hints
The student should know the following terms, theoreticians, and concepts.
Broca’s area
Brain Circuits
Demyelinating disorders
Fibromyalgia
Hemispheric lateralization
HIV-assisted dementia
Human prion diseases
Limbic system
Movement disorders
Neurometabolic syndromes
Questions
Directions
Each of the questions or incomplete statements below is followed by five suggested responses. Select the one that is best in each question.
2.1. Disinhibition is associated with which of the following brain areas or localizations?
A. Left frontal lobe
B. Third frontal gyrus
C. Right frontal lobe
D. Left hemisphere
E. Left limbic area
View Answer
2.1. The answer is C
Although left lateralization of language and right lateralization of visuospatial function are widely recognized, lateral specialization in the prefrontal region is less obvious but still of clinical significance. Frontal lobe degeneration involving the right more than the left frontal lobe is particularly associated with disinhibition. Women tend to show less lateralization of language, so left hemisphere lesions are less likely to produce severe impairment.
2.2. The most common mental disorder associated with cerebrovascular disease is
A. Mania
B. Anxiety
C. Psychosis
D. Alcoholism
E. Depression
View Answer
2.2. The answer is E
Depressive disorders are probably the most common emotional disorder associated with cerebrovascular disease. The prevalence depends upon whether community based samples or hospitalized patients are examined or whether patients with acute stroke or those with chronic stroke are evaluated. Mania and generalized anxiety disorder (GAD) occur much less frequently than depression following stroke.
2.3. The most common site of brain tumors is
A. Frontal lobes
B. Occiput lobes
C. Diencephalic regions
D. Pituitary gland
E. Parietal lobes
View Answer
2.3. The answer is A
The most common sites of brain tumors are the frontal and temporal lobes. The least common sites are the occipital lobes, diencephalic regions, pituitary gland, and parietal and infratentorial areas. Brain tumors are slightly more common in men than in women.
2.4. Epilepsy patients are prone to have which of the following psychiatric conditions?
A. Psychosis
B. Depression
C. Personality Disorders
D. Hyposexuality
E. All of the above
View Answer
2.4. The answer is E (all)
Epidemiological studies from communities, psychiatric hospitals, and epilepsy clinics report a 20 to 60 percent prevalence of psychiatric problems among epilepsy patients. Epilepsy patients are prone to psychosis, depression, personality disorders, hyposexuality, and other behavioral disorders. These problems are approximately equally divided between those that occur ictally or periictally and those that occur interictally or are variably related to the ictus. The percentage of epilepsy patients in psychiatric hospitals was also higher than the general prevalence of epilepsy and ranged from 4.7 percent of all inpatients in a British psychiatric hospital to 9.7 percent in a U.S. Veterans Affairs psychiatric facility.
2.5. Which of the following is the single greatest risk factor for traumatic brain injury (TBI)?
A. Male gender
B. Alcohol or drug abuse
C. African American ethnicity
D. Low socioeconomic status
E. None of the above

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