Occlusive Cerebrovascular Disease
Vaso-occlusive Disease
1. True or False. A transient ischemic attack(TIA)is a focal neurological deficit lasting 24 hours but not more than 48 hours. |
false(A TIA, by definition, lasts ≤ 24 hours.) |
G6 p.869:50mm |
2. Complete the following about transient ischemic attack (TIA): |
|
G7 p.1010:55mm |
a. TIA is usually_____. |
short |
|
b. Most last only_____ _____. |
10 minutes |
|
c. 70% last only_____ _____. |
10 minutes |
|
d. 90% last less than_____ _____. |
4 hours |
|
e. If a deficit lasts more than 60 minutes, only_____% resolve in 24 hours. |
14% |
|
3. Complete the following about RIND: |
|
G6 p.869:60mm |
a. RIND stands for r_____i_____n_____d_____. |
reversible ischemic neurologic deficit |
|
b. |
|
|
i. It is defined as a n_____d_____ |
neurologic deficit |
|
ii. that lasts >_____hours but less than_____ _____. |
24 hours; 1 week |
|
iii. Frequency of occurrence is_____%. |
2.5% |
|
4. With atherosclerotic cerebrovascular disease(CVA), atherosclerotic plaques |
|
G7 p1144:70mm |
a. begin to form as early as age_____ |
20 |
|
b. begin on the back wall of the_____ _____ _____ |
common carotid artery |
|
c. risk of CVA correlates with |
|
|
i. s_____ |
stenosis |
|
ii. u_____ |
ulcerations |
|
iii. h_____ |
hypercoagulable |
|
iv. v_____ |
viscosity |
|
5. True or False. Patients with a depressed level of consciousness or an acute fixed deficit should undergo emergency carotid endarterectomy. |
false(These are two contraindications to emergency CEA.) |
G6 p.880:20mm |
Atherosclerotic Cerebrovascular Disease
6. Carotid artery lesions |
|
G7 p.1144:95mm |
a. are considered symptomatic if |
||
i. there is _____ or _____ ischemic episodes |
one or more |
|
ii. in the _____ of the vessel. |
distribution |
|
b. True or False. They are considered asymptomatic if the patient only has |
|
|
i. visual complaints |
true |
|
ii. Dizziness |
true |
|
iii. Syncope |
true |
|
7. In a patient with carotid plaque categorize the following: |
|
G7 p.1144:95mm |
a. blurred vision |
asymptomatic |
|
b. aphasia for less than 24 hours |
symptomatic |
|
c. weakness of arm for 10 min |
symptomatic |
|
d. dizziness |
asymptomatic |
|
8. True or False. The stroke rate in a patient with asymptomatic carotid bruit is approximately |
|
G7 p.1144:108mm |
a. 0% |
false |
|
b. 2% |
true |
|
c. 8% |
false |
|
d. 22% |
false |
|
9. True or False. The central retinal artery is often insufficient in cerebrovascular disease. This artery is a branch of the following: |
|
G7 p.1144:126mm |
a. posterior cerebral artery |
false |
|
b. orbital artery |
false |
|
c. ophthalmic artery |
true |
|
d. M2 |
false |
|
e. anterior communicating artery |
false |
|
10. Retinal insufficiency can manifest by |
|
G7 p.1144:126mm |
a. temporary loss of vision, aka _____ _____ |
amaurosis fugax |
|
b. True or False. Such loss of vision is |
||
i. bilateral |
false |
|
ii. Contralateral |
false |
|
iii. Ipsilateral |
true |
|
iv. Homonymous |
false |
|
c. There are four types. |
|
G7 p.1144:136mm |
i. Type I is called “black curtain” due to _____. |
emboli |
|
ii. Type III is called “gray vision” due to _____. |
hypoperfusion |
|
iii. Type III is associated with migraines and the cause is _____. |
Vasospastic |
|
iv. Type IV is associated with anti cardio lipin antibodies, and the cause is _____. |
miscellaneous |
|
v. Blindness may be _____. |
permanent |
|
11. What are Hollenhorst plaques? |
cholesterol crystal emboli seen on funduscopic examination in patients with carotid artery disease |
G7 p.1145:178mm |
12. Complete the following about the classification of carotid ulcerations: |
|
G7 p.1145:18mm |
a. Type A is s_____ s_____s_____. |
small smooth shallow |
|
b. Type B is l_____ d_____. |
large deep |
|
c. Type C is c_____ c_____. |
complex cavitated |
|
d. Annual stroke rate for type A is _____%. |
0.5% |
|
e. Annual stroke rate for type B is _____%. |
0.4 to 4.5% |
|
f. Annual stroke rate for type C is _____%. |
5 to 7% |
|
13. What is the gold standard for evaluation of carotid artery disease? |
angiography |
G7 p.1145:63mm |
14. In the arteriosclerotic patient what is the risk that angiography will cause a cerebrovascular accident (CVA)? |
Less than 1% risk of CVA |
G7 p.1145:71mm |
15. Complete the following about Nascet study: |
|
G7 p.1145:90mm |
a. Nascet stands for _____. |
North American Symptomatic Carotid Endarterectomy Trial |
|
b. It measures degree of c_____s_____. |
carotid stenosis |
|
c. Formula is _____ =% stenosis |
|
|
d. where N is measured at maximal _____ |
narrowing |
|
e. |
||
i. where D is measured _____ |
distal |
|
ii. to the _____ _____ |
carotid bulb |
|
iii. where the walls become _____ |
parallel |
|
f. Surgery is not indicated for less than _____%. |
40% |
|
16. Complete the following about duplex Doppler ultrasound limitations: |
|
G7 p.1145:165mm |
a. It can’t scan above the angle of the _____. |
Mandible |
|
b. It performs poorly with the _____ _____. |
string sign |
|
c. Depth of penetration is greater with _____ _____. |
lower frequencies |
|
d. Signal definition is better with _____ _____. |
higher frequencies |
|
17. True or False. Ultrasound of the carotid artery is excellent for evaluating patients with “the string sign.” |
false (Ultrasound is very poor for evaluation of such low flow states.) |
G7 p.1145:168mm |
18. The use of magnetic resonance angiography |
|
G7 p.1145:180mm |
a. may demonstrate a flow _____ |
gap |
|
b. which obviates the need for _____. |
angiography |
|
c. It may _____ the degree of carotid stenosis. |
underestimate |
|
19. True or False. The following irreversibly inhibits cyclooxygenase: |
|
G7 p.1146:166mm |
a. ticlodipine |
false |
|
b. aspirin |
true (Aspirin irreversibly inhibits cyclooxygenase preventing synthesis of vascular prostacyclin and platelet thromboxane A2. Platelets cannot resynthesize cyclooxygenase, whereas the vascular tissues do so rapidly.) |
|
c. clopidogrel |
false |
|
d. prednisone |
false |
|
20. Aspirin |
|
G7 p.1147:16mm |
a. The optimal dose for cerebrovascular ischemia is _____. |
debated |
|
b. |
||
i. Risk of stroke after TIA can be reduced by _____to _____% |
25 to 30% |
|
ii. by the use of _____ mg PO per day. |
325 |
|
c. True or False. More mg of ASA is better after TIA. |
false |
|
d. Daily doses of 81 or 325 mgm were _____ than higher doses. |
better |
|
e. CVA, MI and death were reduced to _____% from _____%. |
6.2 from 8.2 |
|
21. Complete the following about Plavix: |
|
G7 p.1147:55mm |
a. Has a lower incidence of _____ |
neutropenia |
|
b. Needs to be taken _____ per day |
once |
|
c. Requires _____ days off the drug to reverse |
5 |
|
22. Complete the following about asymptomatic carotid artery stenosis: |
|
G7 p.1147:120mm |
a. stroke rate of _____% per year |
2% |
|
b. percent that are not disabling is _____% |
50% |
|
c. Carotid endarterectomy may be beneficial for stenosis of more than _____%. |
60% |
|
23. True or False. The annual stroke rate for patients with symptomatic carotid stenosis is |
|
G7 p.1148:95mm |
a. 30% |
false |
|
b. 5% |
false |
|
c. 1 to 3.4% |
true |
|
d. 1% |
false |
|
24. True or False. The Asymptomatic Carotid Atherosclerosis Study (ACAS) found that surgery is moderately beneficial for asymptomatic carotid stenosis ≥ 60%. |
true |
G7 p.1149:20mm |
Carotid Endarterectomy
25. True or False. The North American Symptomatic Carotid Endarterectomy Trial (NASCET) found that in patients with a recent TIA and ipsilateral stenosis > 70%, carotid endarterectomy (CEA) reduced the risk of CVA by |
G7 p.1150:85mm | |
a. 17% |
true (at 18 months follow-up) |
|
b. 80% |
false |
|
c. 60% |
false |
|
d. It did not reduce the risk. |
false |
|
26. The general trend in carotid endarterectomy surgery is to wait only _____ days after CVA to perform an endarterectomy. |
7 |
G7 p.1151:26mm |
27. True or False. Aspirin and dipyridamole have been shown unequivocally to reduce the rate of restenosis after CEA. |
false (The use of these medications has not been shown to reduce the rate of restenosis after CEA.) |
G7 p.1152:145mm |
28. Complete the following about postop check after carotid endarterectomy: |
G7 p.1152:165mm | |
a. Pronator drift to rule out _____ _____ new hemiparesis |
||
b. Dysphasia to rule out _____ _____ _____ |
dominant hemisphere CVA |
|
c. Pupil size to rule out _____ _____ |
Horner syndrome |
|
d. STA pulsations to rule out _____ _____ _____ |
external carotid occlusion |
|
e. Tongue deviation to identify _____ _____ _____ |
XII nerve injury |
|
f. |
||
i. Hoarseness consider _____ _____ |
laryngeal edema |
|
ii. Or _____ _____ nerve injury |
recurrent laryngeal |
|
g. Tracheal deviation to identify postop _____ |
hematoma |
|
29. List postop complications of carotid endarterectomy. |
G7 p.1153:35mm | |
Hint: c-h4arm2s2 |
||
a. c_____ |
cranial nerve injury |
|
b. h_____ |
headache |
|
c. h_____ |
hoarseness |
|
d. h_____ |
hyperperfusion |
|
e. h_____ |
hypertension |
|
f. a_____ |
arteriotomy disruption |
|
g. r_____ |
restenosis |
|
h. m_____ |
morbidity |
|
i. m_____ |
mortality |
|
j. s_____ |
seizures |
|
k. s_____ |
stroke |
|
30. Complete the following about carotid endarterectomy: |
G7 p.1153:40mm | |
a. Morbidity: absolute upper limit is _____%. |
3% |
|
b. Mortality in hospital is _____%. |
1% |
|
31. Complete the following about arteriotomy disruption: |
G7 p.1153:41mm | |
a. Most immediate danger is _____ |
asphyxiation |
|
b. Symptoms and signs |
||
i. Swelling of _____ |
neck |
|
ii. Swallowing _____ |
difficulty |
|
iii. Deviation of _____ |
trachea |
|
iv. Air _____ |
hunger |
|
v. Late _____ _____ |
false aneurysm |
|
32. Complete the following about stroke: |
|
G7 p.1153:83mm |
a. Infarcation incidence: _____% |
5% |
|
b. Hemorrhagic incidence: _____% |
0.6% |
|
33. What is the most common cause of |
G7 p.1153:102mm | |
a. minor post-CEA CVA? |
emboli |
|
b. major post-CEA CVA? |
postoperative ICA occlusion |
|
34. Risk of stroke is related to |
G7 p.1153:107mm | |
a. t_____ |
technique |
|
b. h_____ |
state hypercoaguable |
|
c. h_____ reaction |
heparin |
|
d. Endarterectomy site is t_____ |
thrombogenic |
|
35. Complete the following about seizures: |
|
G7 p.1153:139mm |
a. Most occur postop day _____ to _____ |
5 to 13 |
|
b. Usually _____ |
focal |
|
c. Incidence _____% |
1% |
|
36. Complete the following about restenosis after CEA surgery: |
|
G7 p.1153:150mm |
a. within 2 years is usually due to _____ _____ |
fibrous hyperplasia |
|
b. after 2 years is usually due to _____ |
atherosclerosis |
|
37. Complete the following about late restenosis: |
|
G7 p.1153:152mm |
a. It occurs within the first year in _____%. |
25% |
|
b. If it occurs within 2 years, it is due to f_____ h_____. |
fibrous hyperplasia |
|
c. If it occurs after 2 years, it is due to a _____. |
atherosclerosis |
|
38. Complete the following about cerebral hyperperfusion syndrome: |
|
G7 p.1153:158mm |
a. Due to return of blood to area of lost _____ |
autoregulation |
|
b. Usually from chronic cerebral _____ |
ischemia |
|
c. Secondary to high-grade _____ |
stenosis |
|
d. May result in _____ _____ |
intracerebral hemorrhage |
|
39. True or false. Hoarseness is most likely caused by |
|
G7 p.1153:175mm |
a. superior laryngeal nerve injury |
false |
|
b. laryngeal edema |
true |
|
c. recurrent laryngeal nerve injury |
false |
|
40. Complete the following about hypoglossal nerve injury: |
|
G7 p.1154:16mm |
a. Incidence is _____%. |
1% |
|
b. Tongue deviates _____ _____ _____ of the injury. |
toward the side |
|
c. Unilateral injury causes problem with |
||
i. sp_____ |
speaking |
|
ii. sw_____ |
swallowing |
|
iii. c_____ |
chewing |
|
d. Bilateral injury can cause a_____ o_____. |
airway obstruction |
|
e. It may last as long as _____ months. |
4 months |
|
f. Palsy is a contraindication to doing endarterectomy. |
Contralaterally |
|
41. Complete the following about endarterectomy and vocal cord paralysis: |
|
G7 p.1154:30mm |
a. Incidence is _____%. |
1% |
|
b. Which side would be affected? |
Ipsilateral |
|
c. Due to injury to |
|
|
i. v_____ nerve |
vagus |
|
ii. r_____ l_____ nerve |
recurrent laryngeal |
|
42. Damage to which nerve could cause postoperative lip asymmetry following CEA? (i.e., not due to stroke) |
marginal mandibular branch of facial nerve MMB-VII (usually a retraction injury with the nerve being retracted against the mandible) |
G7 p.1154:37mm |
43. Complete the following about hypertension: |
|
G7 p.1154:42mm |
a. May develop _____ to _____ days after CEA |
5 to 7 |
|
b. Due to loss of the carotid s_____ b_____ reflex |
sinus baroreceptor |
|
44. True or False. Immediately following CEA (i.e., in the post-anesthesia care unit), a patient who developed neurologic deficit in the distribution of the endarterectomized carotid should undergo immediate computed tomography/magnetic resonance imaging (CT/MRI) or angiogram. |
false (The patient should be emergently reexplored. There is no deficit if flow is reestablished in 45 minutes.) |
G7 p.1154:40mm |
45. True or False. When performing CEA, the order of removing clamps after completion of endarterectomy is |
|
G7 p.1154:80mm |
a. internal, common, external carotid |
false |
|
b. internal, external, common carotid |
false |
|
c. external, common, internal carotid |
true (This ensures that any embolic material will be flushed to the external carotid circulation.) |
|
d. The order of removal does not matter. |
false |
|
46. True or False. When performing reexploration of a CEA occlude in the following order: |
|
G7 p.1154:84mm |
a. Internal, common, external |
false |
|
b. Internal, external, common |
false |
|
c. External, common, internal |
false |
|
d. Common, external, internal |
true |
|
47. Complete the following about arteriotomy disruption: |
|
G7 p.1154:125mm |
a. If you notice difficulty breathing _____ _____ |
open wound |
|
b. then i_____. |
Intubate |
|
c. This may be difficult if the _____ is deviated. |
trachea |
|
48. True or False. A patient with disruption of arteriotomy closure following carotid surgery should never be intubated. |
false (Intubation is a high priority.) |
G7 p.1154:137mm |
49. Complete the following about anesthesia and monitoring: |
|
G7 p.1154:165mm |
a. Hemodynamic intolerance to clamping occurs in _____%. |
1 to 4% |
|
b. If identified, place a vascular _____. |
shunt |
|
c. Which is safer: local or general anesthesia? |
no difference |
|
d. Add thiopental to general anesthesia until EEG burst suppression lasts for _____ to _____ seconds. |
15 to 30 |
|
50. True or False. A shunt is commonly used in carotid surgery when the stump pressure is less than |
|
G7 p.1155:48mm |
a. 100 mm Hg |
false |
|
b. 25 mm Hg |
true |
|
c. 1 mm Hg |
false |
|
d. Never use a shunt |
false |
|
51. Surgical results correlate best with _____ neurologic status. |
presenting |
G7 p.1157:75mm |
52. Totally occluded carotid and patient presents with mild neurologic deficit. |
|
G7 p.1157:165mm |
a. Assume _____ occlusion |
chronic |
|
b. Have stroke rate of _____ to _____% per year |
3 to 5% |
|
53. Complete the following about acute carotid occlusion: |
|
G7 p.1157:165mm |
a. Some neurologic deficit in _____ to _____ |
%40 to 70% |
|
b. Mortality: _____ to _____% |
15 to 55% |
|
c. Good recovery in _____ to _____% |
2 to 12% |
|
54. Six of the symptoms of vertebrobasilar insufficiency (VBI) begin with the letter “d.” They are |
|
G7 p.1158:110mm |
a. dr_____ _____ |
drop attack |
|
b. di_____ |
diplopia |
|
c. dy_____ |
dysarthria |
|
d. de_____ _____ _____ |
defect in vision |
|
e. diz_____ |
dizziness |
|
f. de_____ b_____ |
deficit bilaterally (motor and/or sensory) |
|
55. Answer the following about vertebrobasilar insufficiency (VBI): |
|
G7 p.1158:125mm |
a. Clinical diagnosis of VBI requires how many of those criteria? |
2 or more |
|
b. Which symptom suggests: |
|
|
i. Ischemia to the brain? |
diplopia near ocular nuclear |
|
ii. Ischemia to lower brain stem? |
Dysarthria |
|
iii. Ischemia to occipital cortex? |
homonymous hemianopsia |
|
56. Complete the following about vision symptoms: |
|
G7 p.1158:140mm |
a. |
|
|
i. Carotid artery vision symptoms are _____ |
unilateral |
|
ii. For example, a_____ f_____ |
amaurosis fugax |
|
b. |
|
|
i. Vertebral artery symptoms are _____ |
bilateral |
|
ii. For example, h_____ h_____ |
homonymous hemianopsia |
|
57. If a patient has transient episodes of vertigo you may suspect _____. |
VBI |
G7 p.1158:146mm |
58. The most common cause of VBI |
|
G7 p.1158:185mm |
a. is s_____ s_____ |
subclavian steal |
|
b. |
|
|
i. which is r_____ f_____ in the VA |
reversed flow |
|
ii. due to p_____ s_____ |
proximal stenosis |
|
iii. of the s_____ a_____. |
subclavian artery |
|
59. The mainstay treatment of VBI is a_____. |
anticoagulation |
G7 p.1159:70mm |
60. Complete the following regarding bow hunter’s stroke: |
|
G7 p.1159:105mm |
a. Bow hunter’s stroke is caused by occlusion of the _____ _____ |
vertebral artery |
|
b. resulting from _____ _____. |
head rotation |
|
c. Can this occur from forceful treatment by a chiropractor? |
yes |
|
d. The vessel occluded is _____ to the direction of head rotation. |
Contralateral |
|
e. It is more likely in patients with incompetent _____ _____ arteries. |
posterior communicating |
|
f. An appropriate test for this condition is _____ _____ _____. |
dynamic cerebral angiography (DCA) |
|
g. If condition is proved treatment of choice is _____ _____ _____. |
decompression of VA atC1-2 |
|
h. If still symptomatic treatment is_____ _____. |
C1-2 fusion |
|
Cerebral Arterial Dissections
61. True or False. The following are features of cerebral arterial dissections: |
|
G7 p.1160:125mm |
a. Hemorrhage into medial layer |
true |
|
b. Presentation includes pain, subarachnoid hemorrhage (SAH), TIA, and Horner syndrome. |
true |
|
c. Extracranial dissection is treatedsurgically. |
false |
|
d. Intracranial dissections with SAH are treated surgically. |
false |
|
62. True or False. Regarding arterial dissection: |
|
G7 p.1161:22mm |
a. Hemorrhage can occur outside the vascular lumen due to transintimal extravasation of hematoma. |
true |
|
b. The hematoma may dissect the internal elastic membrane from the intima. |
true |
|
c. Subintimal dissection is more common with extracranial lesions. |
false (Subintimal dissection is more common with intracranial dissection—subintimal = intracranial.) |
|
d. Dissection of the internal elastic membrane results in luminal narrowing. |
true |
|
63. Matching. Match the dissection with its location. |
|
G7 p.1161:38mm |
|
|
|
a. intracranial dissection |
|
|
b. extracranial dissection |
|
|
64. Matching. Rank the following dissection sites in order of frequency of occurrence and give their approximate percentages: |
|
G7 p.1161:103mm |
|
|
|
a. ACA/PCA/PICA _____% |
|
|
b. basilar/ICA/MCA _____% |
|
|
c. vertebral _____% |
|
|
65. True or False. Headache usually precedes neurologic deficits by less than 1 hour. |
false (Headache usually precedes deficits by days to weeks.) |
|
66. True or False. The most reliable finding on radiographic examination of suspected arterial dissections is |
|
G7 p.1162:90mm |
a. direct visualization on CT |
false |
|
b. crescent sign on T2-weighted (T2W) axial imaging |
false |
|
c. string sign on angiography |
false |
|
d. double lumen sign on angiography |
true (Double lumen sign on angiography is considered pathognomonic.) |
|
67. True or False. In cerebral arterial dissection the angiographic configuration is expected |
|
G7 p.1162:105mm |
a. to remain stable |
false |
|
b. to resolve or worsen |
true |
|
c. to often change |
true |
|
68. Mortality in cerebral arterial dissections is higher in |
|
G7 p.1162:150mm |
a. _____ lesions |
carotid |
|
b. carotid _____% |
49% |
|
c. vertebrobasilar artery (VBA) _____% |
22% |
|
d. subarachnoid hemorrhage _____% |
24 |
|
e. non-SAH patients _____% |
29 |
|
69. Complete the following regarding carotid dissection: |
|
G7 p.1163:15mm |
a. True or False. The most frequent presenting symptom of spontaneous ICA dissection is |
|
|
i. neck pain |
false (Pain is 9% more common in VBA.) |
|
ii. neck swelling |
false (swelling 2%) |
|
iii. headache |
true (headache 59%) |
|
iv. oculosympathetic palsy (partial Horner syndrome) |
false (30%) |
|
70. Complete the following about vertebral artery dissection: |
|
G7 p.1163:85mm |
a. Categories: |
|
|
i. s_____ |
spontaneous |
|
ii. a_____ |
aneurysmal |
|
iii. t_____ |
traumatic |
|
b. True or False. Frequency: |
|
|
i. Carotid dissections are more common. |
true |
|
ii. Vertebral dissections are more common. |
false |
|
71. Complete the following regarding cerebral arterial dissections: |
|
G6 p.885:150mm |
a. True or False. Posttraumatic ICA dissection injury mechanisms include |
|
|
i. chiropractic manipulation |
true |
|
ii. attempted strangulation |
true |
|
iii. postangiography |
true |
|
iv. hyperextension of neck with ICA stretch |
true (compress ⇒ stretch ⇒ dissection risk poke ⇒ tweak ⇒) |
|
b. After trauma symptoms manifest within_____ hours _____%. |
24 hours; 75% |
G6 p.885:180mm |
c. The most frequent presenting symptom of posttraumatic ICA dissection is _____ _____. |
ischemic symptoms |
|
d. Which is more common: traumatic or spontaneous ICA dissection? |
traumatic |
|
72. True or False. Persistent embolic complications of ICA dissection are indications for the following interventions: |
|
G6 p.886:50mm |
a. interposition venous grafting |
true |
|
b. EC/IC bypass with maintenance of ICA luminal integrity |
false (Extracranial/intracranial [EC/IC] bypass is okay, but once you bypass the clot, close the ICA off to reduce further embolic risk.) |
|
c. carotid ligation alone |
true |
|
d. heparin-warfarin-based anticoagulation with close angiographic observation |
true |
|
73. Complete the following about traumatic dissections: |
|
G7 p.1163:97mm |
a. Occur where VA crosses _____ _____ |
bony prominences |
|
b. Typically the _____ – _____ junction |
C1-2 |
|
c. Can result from |
|
|
i. Manipulation of _____ |
neck |
|
ii. Automobile a_____ |
accidents |
|
iii. C_____ treatment |
chiropractic |
|
iv. Sudden head _____ |
turning |
|
v. Blow to _____ of _____ |
back of neck |
|
d. Can produce massive _____ hematomas |
neck |
G7 p.1164:15mm |
e. |
|
|
i. Angiography demonstrates lesion posterior to the _____ |
atlas |
|
ii. Which is the distal extracranial _____ _____ |
third segment |
|
f. The first and third portions of the VA are _____. |
movable |
|
g. The second and fourth portions are immobilized by _____. |
bone |
|
h. Most commonly angiography |
|
|
i. demonstrates _____ _____ |
irregular stenosis |
|
ii. of the horizontal loops as they pass _____. |
C1 |
|
74. Complete the following about spontaneous dissection: |
|
G7 p.1163:112mm |
a. Tends to be _____ |
intracranial |
|
b. Occur on the _____VA |
dominant |
|
c. Associated with |
|
|
i. f_____ d_____ |
fibromuscular dysplasia |
|
ii. m_____ |
migraine |
|
iii. o_____ c_____ |
oral contraceptives |
|
d. More common in _____ _____ |
young adults |
|
e. Have other sites of dissection _____% |
36% |
|
f. Have bilateral VA dissection _____% |
21% |
|
75. True or False. Dissecting aneurysms of the vertebrobasilar arteries commonly present as |
|
G7 p.1163:125mm |
a. saccular aneurysms |
false |
|
b. fusifom aneurysms |
true |
|
c. subarachnoid hemorrhage |
true |
|
d. are ameniable to clipping |
may be |
|
e. altered consciousness |
true |
|
76. Although most spontaneous vertebral artery dissections are intracranial, those that are extracranial present with _____ _____. |
occipital pain |
G7 p.1163:155mm |
77. True or False. Dissecting aneurysms of the vertebrobasilar arteries commonly present as |
|
G7 p.1163:175mm |
a. saccular aneurysms |
false |
|
b. fusiform dilatation |
true |
|
c. subarachnoid hemorrhage |
true |
|
78. Matching. Match the treatment with the condition. |
|
G7 p. 1164:70mm |
Treatment: |
|
|
|
|
|
Condition: |
|
|
a. subarachnoid hemorrhage |
|
|
b. intradural dissection |
|
|
c. extradural dissections that progress clinically or angiographically despite anticoagulation |
|
|
d. non-hemorrhagic small infarction |
|
G6 p. 886:116mm |
Cerebrovascular Venous Thrombosis
79. True or False. The following are conditions associated with dural sinus thrombosis formation: |
|
G7 p.1166:80mm |
a. oral contraceptives |
true |
|
b. ulcerative colitis |
true |
|
c. dehydration |
true |
|
d. peripheral vascular disease |
false |
|
e. infection |
true |
|
f. hypercoagulable state |
true |
|
g. pregnancy |
true |
|
h. trauma |
true |
|
80. Hypercoagulable state includes |
|
G7 p.1166:135mm |
(Hint: a2p4rs) |
|
|
a. a_____ III deficiency |
antithrombin |
|
b. a_____ antibodies |
antiphospholipid |
|
c. p_____ C deficiency |
protein |
|
d. p_____ S deficiency |
protein |
|
e. p_____ _____ hemoglobinuria |
paroxysmal nocturnal |
|
f. p_____ deficiency |
plasminogen |
|
g. r_____ to activated protein C |
resistance |
|
h. s_____ lupus erythematosis |
systemic |
|
81. Complete the following about cerebrovascular venous thrombosis: |
|
G7 p.1167:15mm |
a. Incidence is 1 in _____ births. |
10,000 |
|
b. Period of highest risk of cerebrovascular venous thrombosis during the puerperium is within the first _____ _____ after delivery. |
2 weeks |
|
82. True or False. Dural sinus thrombosis occurs more often in the superior sagittal sinus and the |
|
G7 p.1167:40mm |
a. right transverse sinus |
false |
|
b. left transverse sinus |
true |
|
c. straight sinus |
false |
|
d. inferior sagittal sinus |
false |
|
83. Incidence of dural sinus thrombosis (DST) |
|
G7 p.1164:47mm |
a. in the superior sagittal sinus is_____% |
70% |
|
b. in the left transverse sinus is _____% |
70% |
|
c. in multiple sinuses is _____% |
71% |
|
84. Complete the following about clinical symptoms from superior sagittal sinus thrombosis (SSS): |
|
G7 p.1167:125mm |
a. No symptoms _____ _____ |
anterior third |
|
b. Spastically, increased muscle tone _____ _____ |
middle third |
|
c. Cortical blindness or edema, or death_____ _____ |
posterior third |
|
85. What are the clinical symptoms of thrombosis of SSS? |
|
G7 p.1167:126mm |
a. Anterior third: may produce _____ _____ |
no symptoms |
|
b. Middle third: may produce _____ |
spasticity |
|
c. Thrombosis of posterior third: may produce _____, _____, _____ |
blindness, edema, death |
|
86. Thrombosis of the jugular bulb may produce the following syndrome: |
|
G7 p.1167:152mm |
a. symptoms (Hint: bash) |
|
|
i. b_____ |
breathlessness |
|
ii. a_____ |
aphonia |
|
iii. s_____ |
swallowing difficulties |
|
iv. h_____ |
hoarseness |
|
b. named _____ _____ |
Vernet syndrome |
also see G6 p.86:140mm |
c. nerves involved are _____ _____ _____ |
9, 10, 11 |
|
d. due to compression of the pars _____ |
nervosa |
|
87. The best way to diagnose thrombosis of a venous sinus is by |
|
G7 p.1167:175mm |
a. M_____ or |
MRI |
|
b. a_____. |
angiography |
|
88. With dural sinus thrombosis and plain CT scan, suspect the diagnosis of DST. |
|
G7 p.1168:20mm |
a. May be _____ in 20% |
normal |
|
b. Intraparenchymal f_____ hemorrhage _____% |
flame; 20% |
|
c. Small v_____ in _____% |
ventricles; 50% |
|
d. White matter e_____ |
edema |
|
e. Above changes occurring b_____ |
bilaterally |
|
89. Thrombosis of the superior sagittal sinus |
|
G7 p.1168:44mm |
a. may produce a configuration on CT scan called a _____ _____, |
delta sign |
|
b. which represents _____ _____ in the _____ |
clotted blood in the sinus |
|
c. or on a CT with contrast it may produce an _____ _____ _____. |
empty delta sign |
|
90. Complete the following about delta sign types: |
|
G7 p1168:46mm |
a. Delta sign—a triangular-shaped configuration—is seen on |
|
|
i. CT _____ contrast |
without |
|
ii. Represents _____ _____ |
clotted blood |
|
iii. _____ the sinus |
within |
|
b. Pseudo delta sign is |
|
|
i. CT _____ contrast |
without |
|
ii. Represents _____ around SSS |
SAH |
|
c. Empty delta sign is seen in |
|
|
i. CT _____ contrast |
with |
|
ii. Represents enhancement of _____ |
dura |
|
iii. More so than the intra sinus _____ |
clot |
|
91. True or False. The following are benefits of assessing thrombosis of the superior sagittal sinus with MRI: |
|
G7 p.1168:95mm |
a. preferred diagnostic procedure |
true |
|
b. can demonstrate vascular changes |
true |
|
c. can demonstrate parenchymal changes |
true |
|
d. can identify congenital absence of sinus |
true |
|
e. shows cerebral edema |
true |
|
f. can estimate age of thrombosis |
true |
|
g. more advantageous than angiography |
true |
|
92. Complete the following regarding cerebrovascular venous thrombosis: |
|
G7 p.1169:65mm |
a. True or False. Heparin is the treatment of choice for dural venous sinus thrombosis with associated intracranial hemorrhage. |
true |
|
b. Must not treat |
|
|
i. with _____ |
steroids |
|
ii. because they reduce _____ and sthereby increase _____ |
fibrinolysis; thrombosis |
|
c. Should also correct |
|
|
i. _____ _____ |
underlying abnormality (i.e., use antibiotics) |
|
ii. and control _____ |
hypertension |
|
d. continue anticoagulation for _____ to _____ months |
3 to 6 |
G7 p.1169:175mm |
93. What is the prognosis of superior sagittal sinus (SSS) thrombosis? |
|
G7 p.1170:65mm |
a. Mortality is _____%. |
5 to 70% (approximately 30%) |
|
b. Poor prognostic indicators are |
|
|
i. e _____ of a_____ |
extremes of age (infancy or old age) |
|
ii. c_____ |
coma |
|
iii. n_____ d_____ |
neurological deterioration (rapid) |
|
c. Treatment for visual loss from papilledema is o_____ n_____ s_____ f_____. |
optic nerve sheath fenestration |
G7 p.1169:170mm |
Moyamoya Disease
94. Complete the following regarding moyamoya disease: |
|
G7 p.1170:125mm |
a. Moyamoya means p_____ o_____ s_____. |
puff of smoke |
|
b. Skull base arteries are _____ |
narrowed |
|
c. due to a thickened _____. |
intima |
|
d. _____ deposits occur |
Lipid |
|
e. without evidence of _____. |
inflammation |
|
f. The other vascular abnormality that occurs is _____, which |
aneurysms (intracranial) |
G7 p.1171:65mm |
g. may be due to a _____ defect in the wall. |
congenital |
|
h. Aneurysms occur in unusual sites. |
|
|
i. Cerebral arteries at their _____ |
periphery |
|
ii. Posterior/anterior _____ |
choroidal |
|
iii. Recurrent artery of _____ |
Heubner |
|
iv. Frequency of VB aneurysms is _____% |
62% |
|
i. The country with highest incidence is_____. |
Japan |
|
j. If untreated the prognosis of major deficit or death in 2 years is _____%. |
73% |
|
k. Treated prognosis is good in _____%. |
58% |
|
95. Presentation in |
|
G7 p.1171:150mm |
a. children is by _____ attacks |
ischemic |
|
b. adults is by _____ |
hemorrhage |
|
c. Diagnose with |
|
|
i. a_____ |
angiography |
|
ii. M_____ |
MRA |
|
d. The best medical treatment is _____. |
none known to be beneficial |
|
e. Surgical treatments all involve _____. |
revascularization |
G7 p.1173:100mm |
f. The surgical procedure of choice is _____ _____ _____. |
superficial temporal artery—middle cerebral artery (STAMCA) bypass |
|
96. What is the treatment for moyamoya disease? |
|
G7 p.1173:120mm |
a. EMS = _____ |
encephalomyosynangiosis |
|
b. EDAS = _____ |
encephaloduroarterio-synangiosis |
|
c. OPT = _____ |
omental pedicle transplantation |
|

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