Occlusive Cerebrovascular Disease

Occlusive Cerebrovascular Disease


Vaso-occlusive Disease
































































































1. True or False. A transient ischemic attack(TIA)is a focal neurological deficit lasting 24 hours but not more than 48 hours.


false(A TIA, by definition, lasts ≤ 24 hours.)


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2. Complete the following about transient ischemic attack (TIA):


 


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a. TIA is usually_____.


short


 


b. Most last only_____ _____.


10 minutes


 


c. 70% last only_____ _____.


10 minutes


 


d. 90% last less than_____ _____.


4 hours


 


e. If a deficit lasts more than 60 minutes, only_____% resolve in 24 hours.


14%


 


3. Complete the following about RIND:


 


G6 p.869:60mm


a. RIND stands for r_____i_____n_____d_____.


reversible ischemic neurologic deficit


 


b.


 


 


     i. It is defined as a n_____d_____


neurologic deficit


 


     ii. that lasts >_____hours but less than_____ _____.


24 hours; 1 week


 


     iii. Frequency of occurrence is_____%.


2.5%


 


4. With atherosclerotic cerebrovascular disease(CVA), atherosclerotic plaques


 


G7 p1144:70mm


a. begin to form as early as age_____


20


 


b. begin on the back wall of the_____ _____ _____


common carotid artery


 


c. risk of CVA correlates with


 


 


     i. s_____


stenosis


 


     ii. u_____


ulcerations


 


     iii. h_____


hypercoagulable


 


     iv. v_____


viscosity


 


5. True or False. Patients with a depressed level of consciousness or an acute fixed deficit should undergo emergency carotid endarterectomy.


false(These are two contraindications to emergency CEA.)


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Atherosclerotic Cerebrovascular Disease




























































































































































































































































































































































































6. Carotid artery lesions


 


G7 p.1144:95mm


a. are considered symptomatic if



     i. there is _____ or _____ ischemic episodes


one or more


 


     ii. in the _____ of the vessel.


distribution


 


b. True or False. They are considered asymptomatic if the patient only has


 


     i. visual complaints


true


 


     ii. Dizziness


true


 


     iii. Syncope


true


 


7. In a patient with carotid plaque categorize the following:


 


G7 p.1144:95mm


a. blurred vision


asymptomatic


 


b. aphasia for less than 24 hours


symptomatic


 


c. weakness of arm for 10 min


symptomatic


 


d. dizziness


asymptomatic


 


8. True or False. The stroke rate in a patient with asymptomatic carotid bruit is approximately


 


G7 p.1144:108mm


a. 0%


false


 


b. 2%


true


 


c. 8%


false


 


d. 22%


false


 


9. True or False. The central retinal artery is often insufficient in cerebrovascular disease. This artery is a branch of the following:


 


G7 p.1144:126mm


a. posterior cerebral artery


false


 


b. orbital artery


false


 


c. ophthalmic artery


true


 


d. M2


false


 


e. anterior communicating artery


false


 


10. Retinal insufficiency can manifest by


 


G7 p.1144:126mm


a. temporary loss of vision, aka _____ _____


amaurosis fugax


 


b. True or False. Such loss of vision is



     i. bilateral


false


 


     ii. Contralateral


false


 


     iii. Ipsilateral


true


 


     iv. Homonymous


false


 


c. There are four types.


 


G7 p.1144:136mm


     i. Type I is called “black curtain” due to _____.


emboli


 


     ii. Type III is called “gray vision” due to _____.


hypoperfusion


 


     iii. Type III is associated with migraines and the cause is _____.


Vasospastic


 


     iv. Type IV is associated with anti cardio lipin antibodies, and the cause is _____.


miscellaneous


 


     v. Blindness may be _____.


permanent


 


11. What are Hollenhorst plaques?


cholesterol crystal emboli seen on funduscopic examination in patients with carotid artery disease


G7 p.1145:178mm


12. Complete the following about the classification of carotid ulcerations:


 


G7 p.1145:18mm


a. Type A is s_____ s_____s_____.


small smooth shallow


 


b. Type B is l_____ d_____.


large deep


 


c. Type C is c_____ c_____.


complex cavitated


 


d. Annual stroke rate for type A is _____%.


0.5%


 


e. Annual stroke rate for type B is _____%.


0.4 to 4.5%


 


f. Annual stroke rate for type C is _____%.


5 to 7%


 


13. What is the gold standard for evaluation of carotid artery disease?


angiography


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14. In the arteriosclerotic patient what is the risk that angiography will cause a cerebrovascular accident (CVA)?


Less than 1% risk of CVA


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15. Complete the following about Nascet study:


 


G7 p.1145:90mm


a. Nascet stands for _____.


North American Symptomatic Carotid Endarterectomy Trial


 


b. It measures degree of c_____s_____.


carotid stenosis


 


c. Formula is _____ =% stenosis


stenosis


d. where N is measured at maximal _____


narrowing


e.



     i. where D is measured _____


distal


     ii. to the _____ _____


carotid bulb


 


     iii. where the walls become _____


parallel


 


f. Surgery is not indicated for less than _____%.


40%


 


16. Complete the following about duplex Doppler ultrasound limitations:


 


G7 p.1145:165mm


a. It can’t scan above the angle of the _____.


Mandible


 


b. It performs poorly with the _____ _____.


string sign


 


c. Depth of penetration is greater with _____ _____.


lower frequencies


 


d. Signal definition is better with _____ _____.


higher frequencies


 


17. True or False. Ultrasound of the carotid artery is excellent for evaluating patients with “the string sign.”


false (Ultrasound is very poor for evaluation of such low flow states.)


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18. The use of magnetic resonance angiography


 


G7 p.1145:180mm


a. may demonstrate a flow _____


gap


 


b. which obviates the need for _____.


angiography


 


c. It may _____ the degree of carotid stenosis.


underestimate


 


19. True or False. The following irreversibly inhibits cyclooxygenase:


 


G7 p.1146:166mm


a. ticlodipine


false


 


b. aspirin


true (Aspirin irreversibly inhibits cyclooxygenase preventing synthesis of vascular prostacyclin and platelet thromboxane A2. Platelets cannot resynthesize cyclooxygenase, whereas the vascular tissues do so rapidly.)


 


c. clopidogrel


false


 


d. prednisone


false


 


20. Aspirin


 


G7 p.1147:16mm


a. The optimal dose for cerebrovascular ischemia is _____.


debated


 


b.



     i. Risk of stroke after TIA can be reduced by _____to _____%


25 to 30%


 


     ii. by the use of _____ mg PO per day.


325


 


c. True or False. More mg of ASA is better after TIA.


false


 


d. Daily doses of 81 or 325 mgm were _____ than higher doses.


better


 


e. CVA, MI and death were reduced to _____% from _____%.


6.2 from 8.2


 


21. Complete the following about Plavix:


 


G7 p.1147:55mm


a. Has a lower incidence of _____


neutropenia


 


b. Needs to be taken _____ per day


once


 


c. Requires _____ days off the drug to reverse


5


 


22. Complete the following about asymptomatic carotid artery stenosis:


 


G7 p.1147:120mm


a. stroke rate of _____% per year


2%


 


b. percent that are not disabling is _____%


50%


 


c. Carotid endarterectomy may be beneficial for stenosis of more than _____%.


60%


 


23. True or False. The annual stroke rate for patients with symptomatic carotid stenosis is


 


G7 p.1148:95mm


a. 30%


false


 


b. 5%


false


 


c. 1 to 3.4%


true


 


d. 1%


false


 


24. True or False. The Asymptomatic Carotid Atherosclerosis Study (ACAS) found that surgery is moderately beneficial for asymptomatic carotid stenosis ≥ 60%.


true


G7 p.1149:20mm


Carotid Endarterectomy








































































































































































































































































































































































































































































































































































































































































25. True or False. The North American Symptomatic Carotid Endarterectomy Trial (NASCET) found that in patients with a recent TIA and ipsilateral stenosis > 70%, carotid endarterectomy (CEA) reduced the risk of CVA by



G7 p.1150:85mm


a. 17%


true (at 18 months follow-up)


 


b. 80%


false


 


c. 60%


false


 


d. It did not reduce the risk.


false


 


26. The general trend in carotid endarterectomy surgery is to wait only _____ days after CVA to perform an endarterectomy.


7


G7 p.1151:26mm


27. True or False. Aspirin and dipyridamole have been shown unequivocally to reduce the rate of restenosis after CEA.


false (The use of these medications has not been shown to reduce the rate of restenosis after CEA.)


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28. Complete the following about postop check after carotid endarterectomy:



G7 p.1152:165mm


a. Pronator drift to rule out _____ _____ new hemiparesis



b. Dysphasia to rule out _____ _____ _____


dominant hemisphere CVA


 


c. Pupil size to rule out _____ _____


Horner syndrome


 


d. STA pulsations to rule out _____ _____ _____


external carotid occlusion


 


e. Tongue deviation to identify _____ _____ _____


XII nerve injury


 


f.



     i. Hoarseness consider _____ _____


laryngeal edema


 


     ii. Or _____ _____ nerve injury


recurrent laryngeal


 


g. Tracheal deviation to identify postop _____


hematoma


 


29. List postop complications of carotid endarterectomy.



G7 p.1153:35mm


Hint: c-h4arm2s2



a. c_____


cranial nerve injury


 


b. h_____


headache


 


c. h_____


hoarseness


 


d. h_____


hyperperfusion


 


e. h_____


hypertension


 


f. a_____


arteriotomy disruption


 


g. r_____


restenosis


 


h. m_____


morbidity


 


i. m_____


mortality


 


j. s_____


seizures


 


k. s_____


stroke


 


30. Complete the following about carotid endarterectomy:



G7 p.1153:40mm


a. Morbidity: absolute upper limit is _____%.


3%


 


b. Mortality in hospital is _____%.


1%


 


31. Complete the following about arteriotomy disruption:



G7 p.1153:41mm


a. Most immediate danger is _____


asphyxiation


 


b. Symptoms and signs



     i. Swelling of _____


neck


 


     ii. Swallowing _____


difficulty


 


     iii. Deviation of _____


trachea


 


     iv. Air _____


hunger


 


     v. Late _____ _____


false aneurysm


 


32. Complete the following about stroke:


 


G7 p.1153:83mm


a. Infarcation incidence: _____%


5%


 


b. Hemorrhagic incidence: _____%


0.6%


 


33. What is the most common cause of



G7 p.1153:102mm


a. minor post-CEA CVA?


emboli


 


b. major post-CEA CVA?


postoperative ICA occlusion


 


34. Risk of stroke is related to



G7 p.1153:107mm


a. t_____


technique


 


b. h_____


state hypercoaguable


 


c. h_____ reaction


heparin


 


d. Endarterectomy site is t_____


thrombogenic


 


35. Complete the following about seizures:


 


G7 p.1153:139mm


a. Most occur postop day _____ to _____


5 to 13


 


b. Usually _____


focal


 


c. Incidence _____%


1%


 


36. Complete the following about restenosis after CEA surgery:


 


G7 p.1153:150mm


a. within 2 years is usually due to _____ _____


fibrous hyperplasia


 


b. after 2 years is usually due to _____


atherosclerosis


 


37. Complete the following about late restenosis:


 


G7 p.1153:152mm


a. It occurs within the first year in _____%.


25%


 


b. If it occurs within 2 years, it is due to f_____ h_____.


fibrous hyperplasia


 


c. If it occurs after 2 years, it is due to a _____.


atherosclerosis


 


38. Complete the following about cerebral hyperperfusion syndrome:


 


G7 p.1153:158mm


a. Due to return of blood to area of lost _____


autoregulation


 


b. Usually from chronic cerebral _____


ischemia


 


c. Secondary to high-grade _____


stenosis


 


d. May result in _____ _____


intracerebral hemorrhage


 


39. True or false. Hoarseness is most likely caused by


 


G7 p.1153:175mm


a. superior laryngeal nerve injury


false


 


b. laryngeal edema


true


 


c. recurrent laryngeal nerve injury


false


 


40. Complete the following about hypoglossal nerve injury:


 


G7 p.1154:16mm


a. Incidence is _____%.


1%


 


b. Tongue deviates _____ _____ _____ of the injury.


toward the side


 


c. Unilateral injury causes problem with



     i. sp_____


speaking


 


     ii. sw_____


swallowing


 


     iii. c_____


chewing


 


d. Bilateral injury can cause a_____ o_____.


airway obstruction


 


e. It may last as long as _____ months.


4 months


 


f. Palsy is a contraindication to doing endarterectomy.


Contralaterally


 


41. Complete the following about endarterectomy and vocal cord paralysis:


 


G7 p.1154:30mm


a. Incidence is _____%.


1%


 


b. Which side would be affected?


Ipsilateral


 


c. Due to injury to


 


 


     i. v_____ nerve


vagus


 


     ii. r_____ l_____ nerve


recurrent laryngeal


 


42. Damage to which nerve could cause postoperative lip asymmetry following CEA? (i.e., not due to stroke)


marginal mandibular branch of facial nerve MMB-VII (usually a retraction injury with the nerve being retracted against the mandible)


G7 p.1154:37mm


43. Complete the following about hypertension:


 


G7 p.1154:42mm


a. May develop _____ to _____ days after CEA


5 to 7


 


b. Due to loss of the carotid s_____ b_____ reflex


sinus baroreceptor


 


44. True or False. Immediately following CEA (i.e., in the post-anesthesia care unit), a patient who developed neurologic deficit in the distribution of the endarterectomized carotid should undergo immediate computed tomography/magnetic resonance imaging (CT/MRI) or angiogram.


false (The patient should be emergently reexplored. There is no deficit if flow is reestablished in 45 minutes.)


G7 p.1154:40mm


45. True or False. When performing CEA, the order of removing clamps after completion of endarterectomy is


 


G7 p.1154:80mm


a. internal, common, external carotid


false


 


b. internal, external, common carotid


false


 


c. external, common, internal carotid


true (This ensures that any embolic material will be flushed to the external carotid circulation.)


 


d. The order of removal does not matter.


false


 


46. True or False. When performing reexploration of a CEA occlude in the following order:


 


G7 p.1154:84mm


a. Internal, common, external


false


 


b. Internal, external, common


false


 


c. External, common, internal


false


 


d. Common, external, internal


true


 


47. Complete the following about arteriotomy disruption:


 


G7 p.1154:125mm


a. If you notice difficulty breathing _____ _____


open wound


 


b. then i_____.


Intubate


 


c. This may be difficult if the _____ is deviated.


trachea


 


48. True or False. A patient with disruption of arteriotomy closure following carotid surgery should never be intubated.


false (Intubation is a high priority.)


G7 p.1154:137mm


49. Complete the following about anesthesia and monitoring:


 


G7 p.1154:165mm


a. Hemodynamic intolerance to clamping occurs in _____%.


1 to 4%


 


b. If identified, place a vascular _____.


shunt


 


c. Which is safer: local or general anesthesia?


no difference


 


d. Add thiopental to general anesthesia until EEG burst suppression lasts for _____ to _____ seconds.


15 to 30


 


50. True or False. A shunt is commonly used in carotid surgery when the stump pressure is less than


 


G7 p.1155:48mm


a. 100 mm Hg


false


 


b. 25 mm Hg


true


 


c. 1 mm Hg


false


 


d. Never use a shunt


false


 


51. Surgical results correlate best with _____ neurologic status.


presenting


G7 p.1157:75mm


52. Totally occluded carotid and patient presents with mild neurologic deficit.


 


G7 p.1157:165mm


a. Assume _____ occlusion


chronic


 


b. Have stroke rate of _____ to _____% per year


3 to 5%


 


53. Complete the following about acute carotid occlusion:


 


G7 p.1157:165mm


a. Some neurologic deficit in _____ to _____


%40 to 70%


 


b. Mortality: _____ to _____%


15 to 55%


 


c. Good recovery in _____ to _____%


2 to 12%


 


54. Six of the symptoms of vertebrobasilar insufficiency (VBI) begin with the letter “d.” They are


 


G7 p.1158:110mm


a. dr_____ _____


drop attack


 


b. di_____


diplopia


 


c. dy_____


dysarthria


 


d. de_____ _____ _____


defect in vision


 


e. diz_____


dizziness


 


f. de_____ b_____


deficit bilaterally (motor and/or sensory)


 


55. Answer the following about vertebrobasilar insufficiency (VBI):


 


G7 p.1158:125mm


a. Clinical diagnosis of VBI requires how many of those criteria?


2 or more


 


b. Which symptom suggests:


 


 


     i. Ischemia to the brain?


diplopia near ocular nuclear


 


     ii. Ischemia to lower brain stem?


Dysarthria


 


     iii. Ischemia to occipital cortex?


homonymous hemianopsia


 


56. Complete the following about vision symptoms:


 


G7 p.1158:140mm


a.


 


 


     i. Carotid artery vision symptoms are _____


unilateral


 


     ii. For example, a_____ f_____


amaurosis fugax


 


b.


 


 


     i. Vertebral artery symptoms are _____


bilateral


 


     ii. For example, h_____ h_____


homonymous hemianopsia


 


57. If a patient has transient episodes of vertigo you may suspect _____.


VBI


G7 p.1158:146mm


58. The most common cause of VBI


 


G7 p.1158:185mm


a. is s_____ s_____


subclavian steal


 


b.


 


 


     i. which is r_____ f_____ in the VA


reversed flow


 


     ii. due to p_____ s_____


proximal stenosis


 


     iii. of the s_____ a_____.


subclavian artery


 


59. The mainstay treatment of VBI is a_____.


anticoagulation


G7 p.1159:70mm


60. Complete the following regarding bow hunter’s stroke:


 


G7 p.1159:105mm


a. Bow hunter’s stroke is caused by occlusion of the _____ _____


vertebral artery


 


b. resulting from _____ _____.


head rotation


 


c. Can this occur from forceful treatment by a chiropractor?


yes


 


d. The vessel occluded is _____ to the direction of head rotation.


Contralateral


 


e. It is more likely in patients with incompetent _____ _____ arteries.


posterior communicating


 


f. An appropriate test for this condition is _____ _____ _____.


dynamic cerebral angiography (DCA)


 


g. If condition is proved treatment of choice is _____ _____ _____.


decompression of VA atC1-2


 


h. If still symptomatic treatment is_____ _____.


C1-2 fusion


 


Cerebral Arterial Dissections

































































































































































































































































































































































































































































61. True or False. The following are features of cerebral arterial dissections:


 


G7 p.1160:125mm


a. Hemorrhage into medial layer


true


 


b. Presentation includes pain, subarachnoid hemorrhage (SAH), TIA, and Horner syndrome.


true


 


c. Extracranial dissection is treatedsurgically.


false


 


d. Intracranial dissections with SAH are treated surgically.


false


 


62. True or False. Regarding arterial dissection:


 


G7 p.1161:22mm


a. Hemorrhage can occur outside the vascular lumen due to transintimal extravasation of hematoma.


true


 


b. The hematoma may dissect the internal elastic membrane from the intima.


true


 


c. Subintimal dissection is more common with extracranial lesions.


false (Subintimal dissection is more common with intracranial dissection—subintimal = intracranial.)


 


d. Dissection of the internal elastic membrane results in luminal narrowing.


true


 


63. Matching. Match the dissection with its location.


 


G7 p.1161:38mm


media; subintima; between media and adventitia


 


 


a. intracranial dissection



 


b. extracranial dissection


,


 


64. Matching. Rank the following dissection sites in order of frequency of occurrence and give their approximate percentages:


 


G7 p.1161:103mm


first; second; third


 


 


a. ACA/PCA/PICA _____%


10%


 


b. basilar/ICA/MCA _____%


30%


 


c. vertebral _____%


60%


 


65. True or False. Headache usually precedes neurologic deficits by less than 1 hour.


false (Headache usually precedes deficits by days to weeks.)


G7 p.1162:22mm


66. True or False. The most reliable finding on radiographic examination of suspected arterial dissections is


 


G7 p.1162:90mm


a. direct visualization on CT


false


 


b. crescent sign on T2-weighted (T2W) axial imaging


false


 


c. string sign on angiography


false


 


d. double lumen sign on angiography


true (Double lumen sign on angiography is considered pathognomonic.)


 


67. True or False. In cerebral arterial dissection the angiographic configuration is expected


 


G7 p.1162:105mm


a. to remain stable


false


 


b. to resolve or worsen


true


 


c. to often change


true


 


68. Mortality in cerebral arterial dissections is higher in


 


G7 p.1162:150mm


a. _____ lesions


carotid


 


b. carotid _____%


49%


 


c. vertebrobasilar artery (VBA) _____%


22%


 


d. subarachnoid hemorrhage _____%


24


 


e. non-SAH patients _____%


29


 


69. Complete the following regarding carotid dissection:


 


G7 p.1163:15mm


a. True or False. The most frequent presenting symptom of spontaneous ICA dissection is


 


 


     i. neck pain


false (Pain is 9% more common in VBA.)


 


     ii. neck swelling


false (swelling 2%)


 


     iii. headache


true (headache 59%)


 


     iv. oculosympathetic palsy (partial Horner syndrome)


false (30%)


 


70. Complete the following about vertebral artery dissection:


 


G7 p.1163:85mm


a. Categories:


 


 


     i. s_____


spontaneous


 


     ii. a_____


aneurysmal


 


     iii. t_____


traumatic


 


b. True or False. Frequency:


 


 


     i. Carotid dissections are more common.


true


 


     ii. Vertebral dissections are more common.


false


 


71. Complete the following regarding cerebral arterial dissections:


 


G6 p.885:150mm


a. True or False. Posttraumatic ICA dissection injury mechanisms include


 


 


     i. chiropractic manipulation


true


 


     ii. attempted strangulation


true


 


     iii. postangiography


true


 


     iv. hyperextension of neck with ICA stretch


true (compress ⇒ stretch ⇒ dissection risk poke ⇒ tweak ⇒)


 


b. After trauma symptoms manifest within_____ hours _____%.


24 hours; 75%


G6 p.885:180mm


c. The most frequent presenting symptom of posttraumatic ICA dissection is _____ _____.


ischemic symptoms


 


d. Which is more common: traumatic or spontaneous ICA dissection?


traumatic


 


72. True or False. Persistent embolic complications of ICA dissection are indications for the following interventions:


 


G6 p.886:50mm


a. interposition venous grafting


true


 


b. EC/IC bypass with maintenance of ICA luminal integrity


false (Extracranial/intracranial [EC/IC] bypass is okay, but once you bypass the clot, close the ICA off to reduce further embolic risk.)


 


c. carotid ligation alone


true


 


d. heparin-warfarin-based anticoagulation with close angiographic observation


true


 


73. Complete the following about traumatic dissections:


 


G7 p.1163:97mm


a. Occur where VA crosses _____ _____


bony prominences


 


b. Typically the _____ – _____ junction


C1-2


 


c. Can result from


 


 


     i. Manipulation of _____


neck


 


     ii. Automobile a_____


accidents


 


     iii. C_____ treatment


chiropractic


 


     iv. Sudden head _____


turning


 


     v. Blow to _____ of _____


back of neck


 


d. Can produce massive _____ hematomas


neck


G7 p.1164:15mm


e.


 


 


     i. Angiography demonstrates lesion posterior to the _____


atlas


 


     ii. Which is the distal extracranial _____ _____


third segment


 


f. The first and third portions of the VA are _____.


movable


 


g. The second and fourth portions are immobilized by _____.


bone


 


h. Most commonly angiography


 


 


     i. demonstrates _____ _____


irregular stenosis


 


     ii. of the horizontal loops as they pass _____.


C1


 


74. Complete the following about spontaneous dissection:


 


G7 p.1163:112mm


a. Tends to be _____


intracranial


 


b. Occur on the _____VA


dominant


 


c. Associated with


 


 


     i. f_____ d_____


fibromuscular dysplasia


 


     ii. m_____


migraine


 


     iii. o_____ c_____


oral contraceptives


 


d. More common in _____ _____


young adults


 


e. Have other sites of dissection _____%


36%


 


f. Have bilateral VA dissection _____%


21%


 


75. True or False. Dissecting aneurysms of the vertebrobasilar arteries commonly present as


 


G7 p.1163:125mm


a. saccular aneurysms


false


 


b. fusifom aneurysms


true


 


c. subarachnoid hemorrhage


true


 


d. are ameniable to clipping


may be


 


e. altered consciousness


true


 


76. Although most spontaneous vertebral artery dissections are intracranial, those that are extracranial present with _____ _____.


occipital pain


G7 p.1163:155mm


77. True or False. Dissecting aneurysms of the vertebrobasilar arteries commonly present as


 


G7 p.1163:175mm


a. saccular aneurysms


false


 


b. fusiform dilatation


true


 


c. subarachnoid hemorrhage


true


 


78. Matching. Match the treatment with the condition.


 


G7 p. 1164:70mm


Treatment:


 


 


medical-anticoagulation; surgical


 


 


Condition:


 


 


a. subarachnoid hemorrhage



 


b. intradural dissection



 


c. extradural dissections that progress clinically or angiographically despite anticoagulation



 


d. non-hemorrhagic small infarction



G6 p. 886:116mm


Cerebrovascular Venous Thrombosis













































































































































































































































































































































































































79. True or False. The following are conditions associated with dural sinus thrombosis formation:


 


G7 p.1166:80mm


a. oral contraceptives


true


 


b. ulcerative colitis


true


 


c. dehydration


true


 


d. peripheral vascular disease


false


 


e. infection


true


 


f. hypercoagulable state


true


 


g. pregnancy


true


 


h. trauma


true


 


80. Hypercoagulable state includes


 


G7 p.1166:135mm


(Hint: a2p4rs)


 


 


a. a_____ III deficiency


antithrombin


 


b. a_____ antibodies


antiphospholipid


 


c. p_____ C deficiency


protein


 


d. p_____ S deficiency


protein


 


e. p_____ _____ hemoglobinuria


paroxysmal nocturnal


 


f. p_____ deficiency


plasminogen


 


g. r_____ to activated protein C


resistance


 


h. s_____ lupus erythematosis


systemic


 


81. Complete the following about cerebrovascular venous thrombosis:


 


G7 p.1167:15mm


a. Incidence is 1 in _____ births.


10,000


 


b. Period of highest risk of cerebrovascular venous thrombosis during the puerperium is within the first _____ _____ after delivery.


2 weeks


 


82. True or False. Dural sinus thrombosis occurs more often in the superior sagittal sinus and the


 


G7 p.1167:40mm


a. right transverse sinus


false


 


b. left transverse sinus


true


 


c. straight sinus


false


 


d. inferior sagittal sinus


false


 


83. Incidence of dural sinus thrombosis (DST)


 


G7 p.1164:47mm


a. in the superior sagittal sinus is_____%


70%


 


b. in the left transverse sinus is _____%


70%


 


c. in multiple sinuses is _____%


71%


 


84. Complete the following about clinical symptoms from superior sagittal sinus thrombosis (SSS):


 


G7 p.1167:125mm


a. No symptoms _____ _____


anterior third


 


b. Spastically, increased muscle tone _____ _____


middle third


 


c. Cortical blindness or edema, or death_____ _____


posterior third


 


85. What are the clinical symptoms of thrombosis of SSS?


 


G7 p.1167:126mm


a. Anterior third: may produce _____ _____


no symptoms


 


b. Middle third: may produce _____


spasticity


 


c. Thrombosis of posterior third: may produce _____, _____, _____


blindness, edema, death


 


86. Thrombosis of the jugular bulb may produce the following syndrome:


 


G7 p.1167:152mm


a. symptoms (Hint: bash)


 


 


     i. b_____


breathlessness


 


     ii. a_____


aphonia


 


     iii. s_____


swallowing difficulties


 


     iv. h_____


hoarseness


 


b. named _____ _____


Vernet syndrome


also see G6 p.86:140mm


c. nerves involved are _____ _____ _____


9, 10, 11


 


d. due to compression of the pars _____


nervosa


 


87. The best way to diagnose thrombosis of a venous sinus is by


 


G7 p.1167:175mm


a. M_____ or


MRI


 


b. a_____.


angiography


 


88. With dural sinus thrombosis and plain CT scan, suspect the diagnosis of DST.


 


G7 p.1168:20mm


a. May be _____ in 20%


normal


 


b. Intraparenchymal f_____ hemorrhage _____%


flame; 20%


 


c. Small v_____ in _____%


ventricles; 50%


 


d. White matter e_____


edema


 


e. Above changes occurring b_____


bilaterally


 


89. Thrombosis of the superior sagittal sinus


 


G7 p.1168:44mm


a. may produce a configuration on CT scan called a _____ _____,


delta sign


 


b. which represents _____ _____ in the _____


clotted blood in the sinus


 


c. or on a CT with contrast it may produce an _____ _____ _____.


empty delta sign


 


90. Complete the following about delta sign types:


 


G7 p1168:46mm


a. Delta sign—a triangular-shaped configuration—is seen on


 


 


     i. CT _____ contrast


without


 


     ii. Represents _____ _____


clotted blood


 


     iii. _____ the sinus


within


 


b. Pseudo delta sign is


 


 


     i. CT _____ contrast


without


 


     ii. Represents _____ around SSS


SAH


 


c. Empty delta sign is seen in


 


 


     i. CT _____ contrast


with


 


     ii. Represents enhancement of _____


dura


 


     iii. More so than the intra sinus _____


clot


 


91. True or False. The following are benefits of assessing thrombosis of the superior sagittal sinus with MRI:


 


G7 p.1168:95mm


a. preferred diagnostic procedure


true


 


b. can demonstrate vascular changes


true


 


c. can demonstrate parenchymal changes


true


 


d. can identify congenital absence of sinus


true


 


e. shows cerebral edema


true


 


f. can estimate age of thrombosis


true


 


g. more advantageous than angiography


true


 


92. Complete the following regarding cerebrovascular venous thrombosis:


 


G7 p.1169:65mm


a. True or False. Heparin is the treatment of choice for dural venous sinus thrombosis with associated intracranial hemorrhage.


true


 


b. Must not treat


 


 


     i. with _____


steroids


 


     ii. because they reduce _____ and sthereby increase _____


fibrinolysis; thrombosis


 


c. Should also correct


 


 


     i. _____ _____


underlying abnormality (i.e., use antibiotics)


 


     ii. and control _____


hypertension


 


d. continue anticoagulation for _____ to _____ months


3 to 6


G7 p.1169:175mm


93. What is the prognosis of superior sagittal sinus (SSS) thrombosis?


 


G7 p.1170:65mm


a. Mortality is _____%.


5 to 70% (approximately 30%)


 


b. Poor prognostic indicators are


 


 


     i. e _____ of a_____


extremes of age (infancy or old age)


 


     ii. c_____


coma


 


     iii. n_____ d_____


neurological deterioration (rapid)


 


c. Treatment for visual loss from papilledema is o_____ n_____ s_____ f_____.


optic nerve sheath fenestration


G7 p.1169:170mm


Moyamoya Disease





























































































































94. Complete the following regarding moyamoya disease:


 


G7 p.1170:125mm


a. Moyamoya means p_____ o_____ s_____.


puff of smoke


 


b. Skull base arteries are _____


narrowed


 


c. due to a thickened _____.


intima


 


d. _____ deposits occur


Lipid


 


e. without evidence of _____.


inflammation


 


f. The other vascular abnormality that occurs is _____, which


aneurysms (intracranial)


G7 p.1171:65mm


g. may be due to a _____ defect in the wall.


congenital


 


h. Aneurysms occur in unusual sites.


 


 


     i. Cerebral arteries at their _____


periphery


 


     ii. Posterior/anterior _____


choroidal


 


     iii. Recurrent artery of _____


Heubner


 


     iv. Frequency of VB aneurysms is _____%


62%


 


i. The country with highest incidence is_____.


Japan


 


j. If untreated the prognosis of major deficit or death in 2 years is _____%.


73%


 


k. Treated prognosis is good in _____%.


58%


 


95. Presentation in


 


G7 p.1171:150mm


a. children is by _____ attacks


ischemic


 


b. adults is by _____


hemorrhage


 


c. Diagnose with


 


 


     i. a_____


angiography


 


     ii. M_____


MRA


 


d. The best medical treatment is _____.


none known to be beneficial


 


e. Surgical treatments all involve _____.


revascularization


G7 p.1173:100mm


f. The surgical procedure of choice is _____ _____ _____.


superficial temporal artery—middle cerebral artery (STAMCA) bypass


 


96. What is the treatment for moyamoya disease?


 


G7 p.1173:120mm


a. EMS = _____


encephalomyosynangiosis


 


b. EDAS = _____


encephaloduroarterio-synangiosis


 


c. OPT = _____


omental pedicle transplantation


 


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Aug 6, 2016 | Posted by in NEUROSURGERY | Comments Off on Occlusive Cerebrovascular Disease

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