6 Pathological CSF Cell Findings in Cysts The 1993 classification of the World Health Organization (WHO) still grouped cysts and tumorlike lesions together under a single heading that encompassed Rathke cysts, epidermoid cysts, colloid cysts of the third ventricle, and nasal glioma (nasal glial heterotopia). The current classification (2000) no longer counts the various types of central nervous system (CNS) cyst among tumors of the CNS. Nevertheless, we have included them in this atlas because they can shed cells of relatively characteristic types into the cerebrospinal fluid (CSF), which can occasionally be confused with tumor cells. From the point of view of the CSF cytologist, the more important types of CNS cyst are epidermoid cysts (cholesteatoma) and dermoid cysts, as these can manifest themselves through meningeal irritative forms (re-active forms), as seen in Figures 6.1–6.5. Epithelial cells can become trapped in the brain during development as the neural tube closes and later develop into a variety of lesions, most commonly dermoid and epidermoid cysts. Dermoid cysts can also arise from undifferentiated teratomas (see Chapter 5
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PROTHROMBOTIC STATES AND RELATED CONDITIONS
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