POSA After Maxillomandibular Advancement in Patients with Severe OSA


Patient no.

AHI

AHI supine

AHI non-supine

% supine position

Desaturation index

Baseline

After MMA

Baseline

After MMA

Baseline

After MMA

Baseline

After MMA

Baseline

After MMA

1

46,6

4,9

77,8

13,3

39,3

1,2

18,8

30,7

48,0

3,9

2

35,6

12,5

81,7

24,0

29,2

3,2

12,3

44,8

28,2

7,2

3

68,2

28,2

82,0

31,0

48,4

4,6

59,1

89,3

53,0

25,0

4

82,2

40,9

88,8

69,1

71,8

22,6

62,2

39,3

75,6

13,6

5

38,2

24,0

53,2

49,3

33,1

9,4

28,2

36,5

27,1

19,1

6

50,7

14,9

86,5

28,0

30,8

3,8

35,8

45,9

52,9

14,4

7

64,1

20,6

76,0

36,9

54,4

0,6

45,7

53,4

62,9

17,7

8

66,9

14,8

64,1

18,1

82,1

3,8

84,7

78,0

69,4

9,2

9

57,0

27,0

60,2

62,4

49,1

2,5

70,7

40,9

48,6

22,3


AHI Apnea–Hypopnea Index, MMA maxillomandibular advancement



Average follow-up interval for the second PSG recording was 5.9 ± 3.9 months after surgery. Table 2 shows the averages of the polysomnographic results pre and post MMA. A significant decrease in all polysomnographic parameters was seen following MMA surgery. However, the mean supine AHI was still >30. The mean supine AHI decreased from 74.5 to 36.9; this is a reduction of 50.5 %. The mean AHI in lateral sleep positions both decreased even more: right sleep position 42.4–7.0 (83.5 %) and left sleep position 52.7–4.8 (90.9 %). These results are shown in Fig. 1. The BMI did not change significantly postoperatively.


Table 2
Comparison of pre- and post-MMA results







































Characteristics

Pre

Mean ± SD

Post

Mean ± SD

Wilcoxon signed-ranks

p-value

BMI

28.3 ± 3.3

27.3 ± 3.3

0.123

Total AHI

56.6 ± 15.3

20.9 ± 10.6

<0.01

Total AHI supine

74.5 ± 12.4

36.9 ± 19.5

0.01

Total AHI non-supine

48.7 ± 18.4

5.7 ± 6.8

<0.01

Desaturation index

51.7 ± 16.6

14.7 ± 7.0

<0.01


SD standard deviation, AHI Apnea–Hypopnea Index


A311166_1_En_29_Fig1_HTML.gif


Fig. 1
Pre- and postoperative results of MMA

The patients’ dental characteristics are shown in Table 3. Different parameters of the MMA are demonstrated per patient. The pharyngeal airway space (PAS) is defined as the smallest airway space measured on a lateral cephalogram in millimeters pre- and postoperatively. All patients have an increased PAS after MMA with a mean increase from 6.1 to 13.6 mm. The advancement of the maxilla is shown in the cephalometric angle between point sella, nasion, and frontal bone of the maxilla, defined as SNA in amount of degrees. All patients have an increased angle after MMA with a mean of 82.6–88.1°. The advancement of the mandible is measured on a panoramic radiograph and has a mean increase of 8.2 mm after advancement.


Table 3
Polysomnographic and clinical variables of the study group





















































































Patient no.

PAS in mm

Advancement SNA angle

Advancement mandible

Baseline

After MMA

Baseline

After MMA

Baseline

1

4

14

88

102

11

2

6

10

79

89

8

3

7

12

82

87

8

4

4

10

84

85

7

5

8

24

90

94

10

6

5

15

79

85

7

7

4

12

78

85

5

8

10

13

83

84

10

9

7

12

80

82

8

Oct 17, 2016 | Posted by in PSYCHIATRY | Comments Off on POSA After Maxillomandibular Advancement in Patients with Severe OSA

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