Recovery and End-of-Life Care
Questions
1. Which of the following treatment strategies has the strongest evidence supporting efficacy for motor recovery after stroke?
A. Fluoxetine
B. Peripheral electrical stimulation
C. Task practice
D. Transcranial magnetic stimulation
E. Choices A and B are both correct
View Answer
1. Answer C. (MN-157) Task practice is a well-studied and moderately effective therapy for motor weakness after stroke. Transcranial magnetic stimulation remains under study as a potential facilitator of motor recovery, with mixed results to date. Fluoxetine and other selective serotonin reuptake inhibitors (SSRIs) have been found ineffective for motor recovery after stroke in large well-controlled randomized trials and are not recommended for this purpose. Peripheral nerve stimulation has mixed evidence of efficacy for motor recovery. Novel stroke recovery strategies including epidural spinal cord stimulators are in development and hold some promise.
2. In order to maximize motor outcomes, rehabilitation after stroke is optimized when which of the following occurs?
A. When rehabilitation involving a combination of compensatory and recovery training occurs multiple times a day after initiation post stroke
B. When rehabilitation is continued for a minimum of 6 months
C. When rehabilitation is delayed at least 2 weeks to avoid worsening the damage to the brain
D. When rehabilitation is initiated in high doses within 24 hours after stroke
E. When rehabilitation sessions occur at the same time every day
View Answer
2. Answer A. (MN-157) Overall, there remains substantial uncertainty about the optimal timing, intensity, and duration of motor retraining after stroke. However, there are data that engagement in rehabilitation sessions several times daily holds the most benefit. Compensation teaches techniques that leverage preserved neurologic function to adapt and manage neurologic impairment. Enhancing neurologic recovery entails the augmentation of endogenous neuroplastic processes and the facilitation of functional return. There is evidence that intense high-dose motor retraining initiated within the first 24 hours after a stroke may actually inhibit recovery. Conversely, delaying all rehabilitation therapy for 2 weeks would miss a key opportunity to engage injury-related neuroplasticity and is not recommended. While continuing therapy for 6 months may be appropriate for some stroke survivors, there is no specific evidence that this should represent the standard practice.
3. Bladder function after spinal cord injury:
A. inevitably requires an indwelling catheter
B. is easily managed with antispasmodic monotherapy
C. is typically unaffected
D. may require intermittent catheterization indefinitely
E. Choices A and B are both correct
View Answer
3. Answer D. (MN-157) Bladder dysfunction is very common after spinal cord injury and often involves complex issues, such as detrusor-sphincter dyssynergia, where there is a loss of normal coordination between bladder contraction and sphincter relaxation. For this reason, antispasmodics are often insufficient as monotherapy to manage bladder issues in this population. The use of indwelling Foley catheters is associated with a high rate of recurrent urinary tract infections and is to be avoided whenever possible, in favor of intermittent catheterization if spontaneous bladder emptying is ineffective.
4. When comparing inpatient rehabilitation units/hospitals and skilled nursing facilities, they:
A. are very similar and simply vary based on local preference and geography
B. provide comparable amounts of rehabilitation but different amounts of medical and nursing supervision
C. Provide different amounts of rehabilitation but comparable medical and nursing supervision
D. Provide different levels of rehabilitation, nursing, and medical supervision
E. Choices A and B are both correct
View Answer
4. Answer D. (MN-157) Inpatient rehabilitation units/hospitals provide a very different care environment than most skilled nursing facilities with regard to physician involvement, nursing care, and rehabilitation therapies. Daily physician visits, higher nursing ratios, and at least 3 hours of rehabilitation therapies (physical, occupational, and speech therapy) are typical in rehabilitation units/hospitals. Skilled nursing facilities provide less frequent physician visits, have lower ratios of nurses to patients, and typically provide 0.5 to 2 hours of rehabilitation therapy per day.
5. Dysphagia from neurologic disorders:
A. can be fully assessed and managed through a careful bedside physical examination
B. generally requires a gastrostomy tube to provide adequate nutrition
C. is an important target of physical therapy treatment
D. is rare after neurological injury
E. may be managed with modified diets and other swallowing strategies
View Answer
5. Answer E. (MN-158) Many patients with dysphagia from neurological disorders can continue to rely on oral nutrition with modifications of their diet (eg, thickened liquids) and other swallowing strategies. While a bedside clinical evaluation is a key component of screening for dysphagia after stroke and other neurological disorders, it provides limited information about swallowing safety, and individuals with dysphagia identified at bedside frequently require a video fluoroscopic or flexible endoscopic evaluation of swallowing to further characterize their dysphagia and determine the most appropriate management strategy. Gastrostomy tubes are needed for some individuals with more severe dysphagia, and use varies by underlying disorders, anticipated duration of gastrostomy, and patient/family preference. Swallowing therapy is typically provided primarily by speech/language pathologists in the United States, not physical therapists.
6. You are caring for a 44-year-old man with relapsing remitting multiple sclerosis (MS) who presents for follow-up after a recent admission for transverse myelitis secondary to an MS flair. Prior to this admission, he ambulated with cane, but he now requires a rolling walker. You discuss trialing a new disease-modifying agent in addition to a palliative care consultation. In discussion with palliative care team, how would you classify your patient’s disease trajectory?
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