Relapse Prevention
Although the majority of acutely depressed patients are successfully treated either pharmacologically or psychologically, or with a combination of both, the current concern is that many of these successfully treated patients will relapse in the future. Follow-up research from across the globe is showing a return of new episodes of depression in people with a history of depression (Segal, Williams, & Teasdale, 2002) and the current alarming consensus is that relapse and recurrence is common among successfully treated depressed patients. For example, Paykel et al. (1995) found at least 50% of patients who recover from an initial episode of depression will have at least one subsequent depressive episode, and those patients with a history of two or more past episodes will have a 70% to 80% likelihood of recurrence in their lives (Consensus Developmental Panel, 1985). These findings led Judd (1997) to conclude that “unipolar depression is a chronic, lifelong illness, the risk for repeated episodes exceeds 80%, patients will experience an average of four lifetime major depressive episodes of 20 weeks’ duration each” (p. 990).
These findings draw attention to the fact that relapse and recurrence following successful treatment of depression is common. Prior to these findings, relatively little attention was paid to depressed patients’ ongoing risk. Now clinicians and therapists are beginning to make concerted effort to prevent recurrence and relapse in their depressed patients. Continuation treatment and ongoing education regarding warning signs of relapse or recurrence are considered essential in ongoing clinical care. From the review of the literature, Dobson and Ottenbreit (2004) have identified three approaches for relapse prevention: (a) optimizing acute-phase treatment, (b) treating residual symptoms and maintenance treatment, and (c) developing specific relapse-prevention programs. Both pharmacological and psychotherapeutic strategies are used to optimize treatment during the acute phase in order to reduce the risk of relapse. Recently, hypnotherapy (see Alladin, 2006a) has been utilized to prevent relapses in depression. Encouraged by the findings (Alladin, 2005, 2006; Alladin & Alibhai, 2007) that cognitive hypnotherapy (CH) produces larger effect size than cognitive behavioral therapy (CBT) in the management of acute-phase depression and that patients from the CH group continue to improve after discharge, I (Alladin, 2006a) expanded the CH approach to actively deal with relapse prevention. I call this approach experiential cognitive hypnotherapy (ECH) because it uses hypnosis and mindful techniques to help depressed patients decenter from negative feelings, images, and thoughts and search for nondepressive (mainly pleasant) affect. The rest of the chapter will describe how ECH strategies are used to
(a) optimize acute-phase treatment, (b) treat residual symptoms, and (c) provide maintenance treatment. The role pharmacological and other psychotherapeutic approaches is also highlighted.
(a) optimize acute-phase treatment, (b) treat residual symptoms, and (c) provide maintenance treatment. The role pharmacological and other psychotherapeutic approaches is also highlighted.
Optimizing Acute-Phase Treatment
The pharmacological approach focuses on either maintenance medication or having patients strategically cross over from one medication to another if the first medication does not work. Several follow-up studies (Belsher & Costello, 1988; Paykel, et al., 1999; Rafanelli, Park, & Fava, 1999) found that approximately 50% of depressed patients who are in remission or recovered from depression relapse following the discontinuation of either tricyclic antidepressants or selective serotonin reuptake inhibitors (SSRIs). On the basis of these findings the focus of drug treatment in depression has shifted from acute-phase treatment to long-term use of medication for maintenance. Prien and Kupfer (1986) found continuation treatment with antidepressants using the acute-treatment dose to be associated with reduced relapse rates compared to placebo. The optimal length of continuation treatment ranged from 4 to 9 months, and it was notable that a longer time of continuation therapy was not found to be more effective than placebo in preventing relapse (Reimherr, et al., 1998). Regarding the strategy of switching antidepressants, Koran, et al. (2001) found that more aggressive combinations of medication led to better clinical outcome and long-term prognosis than can be obtained from any single medication.
The main psychological approach utilized in the prevention of relapse in depression has been CBT. There is strong evidence that CBT has an enduring effect that reduces subsequent risk for relapse or recurrence following successful treatment (Hollon, Shelton, & Loosen, 1991). Several studies have shown that patients treated to remission with CBT are less likely to relapse after the termination of treatment than are patients treated to remission with medication (e.g., Blackburn, Eunson, & Bishop, 1986; Evans et al., 1992). Gloaguen, et al. (1998), from their meta-analysis of the effects of CBT for depression, concluded that CBT has better outcomes than medication: The average risk of relapse after CBT was 25% as opposed to 60% following pharmacotherapy at follow-up periods of 1 to 2 years. Dobson and Ottenbreit (2004) believe CBT produced better outcome because CBT effects lasting changes in negative cognitions, and it teaches depressed patients coping skills for dealing with stressors that may precipitate a relapse.
CH utilizes several strategies to optimize the acute-phase treatment to prevent relapse. These include:
Systematic CBT
Experiential hypnotherapy
Cognitive restructuring under hypnosis
Expansion of awareness and amplification of experiences
Development of antidepressive pathways
Reduction of guilt and self-blame
Social skills training
Physical exercise
Preparation for discharge from acute-phase treatment
Most these strategies have already been described in Chapters 6,7,8,9,10,11,12,13,14,15. They are briefly described here to highlight how the strategies can be optimized during the acute-phase treatment to prevent relapse and recurrence of depression.
Systematic Cognitive Behavioral Training
The effect of CBT can be optimized by making it as systematic as possible. At least four to six sessions of CH are devoted to CBT, or until the patient has mastered restructuring cognitive distortions using the ABCDE Form (see Chapter 8). It is important that the patient be able to identify, challenge, and correct dysfunctional beliefs that trigger depressive affect. Patients should be coached to differentiate between superficial (“I can’t do this”) and deeper (core beliefs) (“I’m a failure”), and they should be encouraged to constantly monitor and restructure their negative cognitions until it becomes a habit.
Experiential Hypnotherapy
Hypnotherapy, particularly the hypnotic experience, provides a powerful placebo effect to the patient. The therapist can utilize and enhance this effect by inducing positive experience (by creating a pleasant state of mind) and by demonstrating the power of the mind through the cataleptic experience. Also as discussed in Chapter 8 ego-strengthening and posthypnotic suggestions should be realistic and specifically designed to counter rumination with negative self-hypnosis (NSH). As we (Alladin & Heap, 1991, p. 58) have indicated, ego-strengthening should be utilized to exploit “the positive experience of hypnosis and the therapist-patient relationship in order to develop feelings of confidence and optimism and an improved self-image.” The reinforcement of positive affect and self-confidence bolster inner strength and prevent relapse.
Cognitive Restructuring under Hypnosis
To consolidate the effect of cognitive restructuring under hypnosis, the experience must be “syncretic” (a matrix of affective, cognitive, somatic, and behavioral responses), and the cognitive restructuring must be repeated until a set of faulty cognitions related to a specific situation is considered to be successfully restructured (see Chapter 10).
Expansion of Awareness and Amplification of Experiences