Review of Previous Clinical Trials and Guidelines of Cell Therapy


ID

Study

Sponsor (country)

1st received

Condition of patients

Cell source (product code)

Delivery route

Phase

Status of trials

NCT00473057

Study of Autologous Stem Cell Transplantation for Patients With Ischemic Stroke

Universidade Federal do Rio de Janeiro (Brazil)

2007

Acute/subacute

Autologous BM-MNC

I.A.

1

Completed

NCT00535197

Autologous Bone Marrow Stem Cells in Ischemic Stroke

Imperial College London (UK)

2007

Acute

Autologous CD34(+) cells

I.A.

1/2

Completed

NCT00761982

Autologous Bone Marrow Stem Cells in Middle Cerebral Artery Acute Stroke Treatment

Hospital Universitario Central de Asturias (Spain)

2008

Acute

Autologous CD34(+) cells

I.A.

1/2

Completed

NCT00859014

Safety/Feasibility of Autologous Mononuclear Bone Marrow Cells in Stroke Patients

The University of Texas Health Science Center, Houston (USA)

2009

Acute

Autologous BM-MNC

I.V.

1

Completed

NCT00875654

Intravenous Stem Cells After Ischemic Stroke (ISIS)

University Hospital, Grenoble (France)

2009

Acute

Autologous MSC

I.V.

2

Active, not recruiting

NCT00950521

Efficacy Study of CD34 Stem Cell in Chronic Stroke Patients

China Medical University Hospital (China)

2009

Chronic

Autologous CD34(+) cells

I.C.

2

Completed

NCT01151124

Pilot Investigation of Stem Cells in Stroke (PISCES)

ReNeuron Limited (UK)

2010

Chronic

Allogeneic NSC (CTX0E03)

I.A.

1

Active, not recruiting

NCT01287936

A Study of Modified Stem Cells in Stable Ischemic Stroke

SanBio, Inc. (USA)

2011

Chronic

Allogeneic MSC (SB623)

I.A.

1/2

Active, not recruiting

NCT01297413

A Study of Allogeneic Mesenchymal Bone Marrow Cells in Subjects With Ischemic Stroke

Stemedica Cell Technologies, Inc. (USA)

2011

Chronic

Allogeneic MSC

I.V.

1/2

Active, not recruiting

NCT01310114

Study of Human Placenta-derived Cells (PDA001) to Evaluate the Safety and Effectiveness for Patients With Ischemic Stroke

Celgene Corporation (USA)

2011

Acute

Allogeneic placenta-derived cells (PDA001)

I.V.

2

Terminated

NCT01436487

Study to Examine the Effects of MultiStem in Ischemic Stroke

Athersys, Inc (USA)

2011

Acute

Allogeneic MSC (MultiStem)

I.V.

2

Completed

NCT01461720

Intravenous Autologous Mesenchymal Stem Cells Transplantation to Treat Middle Cerebral Artery Infarct

National University of Malaysia (Malaysia)

2011

Acute

Autologous MSC

I.V.

2

Recruiting

NCT01468064

Autologous Bone Marrow Stromal Cell and Endothelial Progenitor Cell Transplantation in Ischemic Stroke (AMETIS)

Southern Medical University (China)

2011

Acute

Autologous MSC, autologous EPC

I.V.

1/2

Recruiting

NCT01501773

Intravenous Autologous Bone Marrow-derived Stem Cells Therapy for Patients With Acute Ischemic Stroke

Manipal Acunova Ltd. (India)

2011

Acute

Autologous BM-MNC

I.V.

2

Completed

NCT01678534

Reparative Therapy in Acute Ischemic Stroke With Allogenic Mesenchymal Stem Cells From Adipose Tissue, Safety Assessment, a Randomised, Double Blind Placebo Controlled Single Center Pilot Clinical Trial (AMASCIS-01)

Instituto de Investigación Hospital Universitario La Paz (Spain)

2012

Acute

Allogenic AT-MSC

I.V.

2

Recruiting

NCT01714167

Autologous Bone Marrow Mesenchymal Stem Cell Transplantation for Chronic Stroke

Wenzhou Medical University (China)

2012

Subacute/chronic

Autologous MSC

I.C.

1

Recruiting

NCT01716481

The STem Cell Application Researches and Trials In NeuroloGy-2 (STARTING-2) Study

Samsung Medical Center (Korea)

2012

Acute/subacute

Autologous MSC

I.V.

3

Recruiting

NCT01832428

A Clinical Trial to Study the Safety and Efficacy of Bone Marrow Derived Autologous Cell for the Treatment of Stroke (BMACS)

Chaitanya Hospital, Pune (India)

2013

Cerebral infarct or hemorrhage

Autologous BM-MNC

I.T.

1/2

Recruiting

NCT01922908

Mesenchymal Stromal Cells for Ischemic Stroke (SAMCIS)

The University of Texas Health Science Center, Houston (USA)

2013

Acute

Allogeneic MSC

I.V.

1/2

Not yet recruiting

NCT02065778

Safety and Efficacy of Autologous Stem Cell Therapy in Chronic Stroke

Neurogen Brain and Spine Institute (India)

2014

Chronic

Autologous BM-MNC

I.T.

1

Completed

NCT02117635

Pilot Investigation of Stem Cells in Stroke Phase II Efficacy (PISCES-II)

ReNeuron Limited (UK)

2014

Subacute

Allogeneic NSC (CTX DP)

I.C.

2

Recruiting

NCT02245698

Autologous Stem Cell Therapy in Stroke

Neurogen Brain and Spine Institute (India)

2014

Subacute/chronic

Autologous BM-MNC

I.T.

1

Recruiting

NCT02283879

Human Umbilical Cord Mesenchymal Stem Cell in Cerebral Hemorrhage Sequela

Shenzhen Hornetcorn Bio-technology Company, LTD (China)

2014

Chronic cerebral hemorrhage

Allogeneic UC-MSC

I.V.

1

Active, not recruiting

NCT02378974

Evaluation of the Safety and Potential Therapeutic Effects After Intravenous Transplantation of Cordstem-ST in Patients With Cerebral Infarction

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Oct 11, 2017 | Posted by in NEUROLOGY | Comments Off on Review of Previous Clinical Trials and Guidelines of Cell Therapy

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