Braun-Menéndez E, Fasciolo JC, Leloir LF, Muñoz JM. The substance causing renal hypertension. J Physiol. 1940;98:283–98.PubMedCentralPubMed

Lavoie JL, Sigmund CD. Minireview: overview of the renin-angiotensin system—an endocrine and paracrine system. Endocrinology. 2003;144:2179–83.PubMed

Danser AH. Local renin-angiotensin systems: the unanswered questions. Int J Biochem Cell Biol. 2003;35:759–68.PubMed

Iwai N, Inagami T. Identification of two subtypes in the rat type 1 angiotensin II receptor. FEBS Lett. 1992;298:257–60.PubMed

Kakar SS, Sellers JC, Devor DC, Musgrove LC, Neill JD. Angiotensin II type-1 receptor subtype cDNAs: differential tissue expression and hormonal regulation. Biochem Biophys Res Commun. 1992;31:1090–6.

Sadamura H, Hein L, Kriegger JE, Pratt RE, Kobilka BK, Dzau V. Cloning, characterization, and expression of two angiotensin receptor (AT-1) isoforms from the mouse genome. Biochem Biophys Res Commun. 1992;185:253–9.

Konoshi H, Kuroda S, Inada Y, Fujisawa Y. Novel subtype of human angiotensin II type 1 receptor: cDNA cloning and expression. Biochem Biophys Res Commun. 1994;199:467–74.

Saavedra JM. Brain and pituitary angiotensin. Endocr Rev. 1992;13(2):329–80.PubMed

Thomas WG, Mendelsohn FAO. Molecules in focus: angiotensin receptors form and function and distribution. Int J Biochem Cell Biol. 2003;35:774–9.PubMed

Rose JM, Audus KL. AT1 receptors mediate angiotensin II uptake and transport by bovine brain microvessel endothelial cells in primary culture. J Cardiovasc Pharmacol. 1999;33(1):30–5.PubMed

de Gasparo M, Catt KJ, Inagami T, Wright JW, Unger T. International union of pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev. 2000;52(3):415–72.PubMed

Hunyady L, Catt KJ. Pleiotropic AT1 receptor signaling pathways mediating physiological and pathogenic actions of angiotensin II. Mol Endocrinol. 2006;20(5):953–70.PubMed

Timmermans PB, Wong PC, Chiu AT, Herblin WF, Benfield P, Carini DJ, et al. Angiotensin II receptors and angiotensin II receptor antagonists. Pharmacol Rev. 1993;45(2):205–51.PubMed

Barnes JM, Steward LJ, Barber PC, Barnes NM. Identification and characterisation of angiotensin II receptor subtypes in human brain. Eur J Pharmacol. 1993;230(3):251–8.PubMed

Clauser E, Curnow KM, Davies E, Conchon S, Teutsch B, Vianello B, et al. Angiotensin II receptors: protein and gene structures, expression and potential pathological involvements. Eur J Endocrinol. 1996;134(4):403–11.PubMed

Saavedra JM, Ando H, Armando I, Baiardi G, Bregonzio C, Juorio A, et al. Anti-stress and anti-anxiety effects of centrally acting angiotensin II AT1 receptor antagonists. Regul Pept. 2005;128:237–8.

Mendelsohn FAO, Quirion R, Saavedra JM, Aguilera G, Catt KJ. Autoradiographic localization of angiotensin II receptors in rat brain. Proc Natl Acad Sci USA. 1984;81:1575–9.PubMedCentralPubMed

Daubert DL, Meadows GG, Wang JH, Sanchez PJ, Speth RC. Changes in angiotensin II receptors in dopamine-rich regions of the mouse brain with age and ethanol consumption. Brain Res. 1999;816:8–16.PubMed

Wright JW, Harding JW. The brain angiotensin system and extracellular matrix molecules in neural plasticity, learning and memory. Prog Neurobiol. 2004;72:263–93.PubMed

Fogarty DJ, Matute C. Angiotensin receptor-like immunoreactivity in adult brain white matter astrocytes and oligodendrocytes. Glia. 2001;35(2):131–46.PubMed

Phillips MI, Sumners C. Angiotensin II in the central nervous system physiology. Regul Pept. 1998;78:1–11.PubMed

Tsutsumi K, Saavedra JM. Characterization and development of angiotensin II receptor subtypes (AT1 and AT2) in rat brain. Am J Physiol. 1991;261:R209–16.PubMed

Schulkin J. Angst and the amygdala. Dialogues Clin Neurosci. 2006;8(4):407–16.PubMedCentralPubMed

Llano Lopez LH, Caif F, Garcia S, Fraile M, Landa AI, Baiardi G, et al. Anxiolytic-like effect of losartan injected into amygdala of the acutely stressed rats. Pharmacol Rep. 2012;64(1):54–63.PubMed

Lenkei Z, Palkovits M, Corvol P, Llorens-Cortes C. Distribution of angiotensin type 1 receptor messenger RNA expression in the adult rat brain. Neuroscience. 1998;82:827–41.PubMed

Carrasco GA, Van de Kar LD. Neuroendocrine pharmacology of stress. Eur J Pharmacol. 2003;463(1–3):235–72.PubMed

Berridge CW, Waterhouse BD. The locus coeruleus-noradrenergic system: modulation of behavioral state and state-dependent cognitive processes. Brain Res Rev. 2003;42:33–84.PubMed

Bali A, Jaggi AS. Angiotensin as stress mediator: role of its receptor and interrelationships among other stress mediators and receptors. Pharmacol Res. 2013;76:49–57.PubMed

Wang G, Anrather J, Huang J, Speth RC, Pickel VM, Iadecola C. NADPH oxidase contributes to angiotensin II signaling in the nucleus tractus solitarius. J Neurosci. 2004;24(24):5516–24.PubMed

Saavedra JM, Sanchez-Lemus E, Benicky J. Blockade of brain angiotensin II AT1 receptors ameliorates stress, anxiety, brain inflammation and ischemia: therapeutic implications. Psychoneuroendocrinology. 2011;36(1):1–18.PubMedCentralPubMed

Bregonzio C, Seltzer A, Armando I, Pavel J, Saavedra JM. Angiotensin II AT(1) receptor blockade selectively enhances brain AT(2) receptor expression, and abolishes the cold-restraint stress-induced increase in tyrosine hydroxylase mRNA in the locus coeruleus of spontaneously hypertensive rats. Stress. 2008;11(6):457–66.PubMedCentralPubMed

Baxter CR, Horvath JS, Duggin GG, Tiller DJ. Effect of age on specific angiotensin II-binding sites in rat brain. Endocrinology. 1980;106(3):995–9.PubMed

Israel A, Stromberg C, Tsutsumi K, Garrido MR, Torres M, Saavedra JM. Angiotensin II receptor subtypes and phosphoinositide hydrolysis in rat adrenal medulla. Brain Res Bull. 1995;38(5):441–6.PubMed

Voigt JP, Hortnagl H, Rex A, van Hove L, Bader M, Fink H. Brain angiotensin and anxiety-related behavior: the transgenic rat TGR(ASrAOGEN)680. Brain Res. 2005;1046(1–2):145–56.PubMed

Belcheva I, Georgiev V, Chobanova M, Hadjiivanova C. Behavioral effects of angiotensin II microinjected into CA1 hippocampal area. Neuropeptides. 1997;31(1):60–4.PubMed

Aguilera G, Young WS, Kiss A, Bathia A. Direct regulation of hypothalamic corticotropin -releasing hormone neurons by angiotensin II. Neuroendocrinology. 1995;61:437–44.PubMed

Armando I, Carranza A, Nishimura Y, Hoe KL, Barontini M, Terrón JA, et al. Peripheral administration of an angiotensin II AT1 receptor decreases the hypothalamic-pituitary-adrenal response to stress. Endocrinology. 2001;142:3880–9.PubMed

Ganong WF, Murakami K. The role of angiotensin II in the regulation of ACTH secretion. Ann N Y Acad Sci. 1987;512:176–86.PubMed