Sedation is sometimes reported as fatigue by patients. Fatigue or sedation can be caused by many systemic illnesses. In psychiatric patients, it could be a potential side effect of medications or a consequence of insomnia from the underlying illness. Obstructive sleep apnea (OSA) is a frequently unrecognized cause of poor sleep and daytime sedation. As OSA is associated with serious cardiovascular comorbidities, patients reporting poor sleep should be screened. Asking about snoring and apneic breathing and assessing for risk factors of obesity and hypertension are sufficient for initial screening.