Skin Ailments—Acne Vulgaris
Acne vulgaris
General—disease of the pilosebaceous glands
Pathology—increased sebum, hyperkeratinization, accumulation of debris, and Propionibacterium acnes colonization
Clinical—occurs in areas with most pilosebaceous glands (face, neck, chest, back, and upper arms.)
Risk factors
Classification
Mild—few to several papules and pustules; no nodules
Moderate—several to many papules and pustules; few to several nodules
Severe—many papules, pustules, and nodules
Note: Inflammatory acne involves the presence of pustules and cysts.
Treatment
Topical agents
Topical retinoids (for mild acne; prevents obstruction of pilosebaceous glands)
Tretinoin topical (Retin-A)—apply qhs 30 minutes after drying skin.
Adverse effects—thins stratum corneum, pregnancy class C
Adapalene (Differin)—apply 1 hour before bedtime
Adverse effects—pregnancy class C.
Note: With all retinoids, allow 8 to 12 weeks of treatment for results.
Topical antibiotics (for mild to moderate inflammatory acne)
Clindamycin topical (Cleocin T, ClindaMAX)—apply BID.Stay updated, free articles. Join our Telegram channel
Full access? Get Clinical Tree