and Marcos Soares Tatagiba2
(1)
Chairman of the Neurosurgical Department, Neurological Institute of Curitiba, Curitiba, Brazil
(2)
Chairman of the Neurosurgical Department, Eberhard Karls University, Tübingen, Germany
Keywords
Surgical approachesRetrosigmoid approachCranio-cervical approachCranial base reconstructionPostoperative managementSurgical Approaches
Most authors use the postauricular infratentorial surgical approaches proposed by Fisch [1] to treat glomus tumors. Three distinct variations of Fisch’s approaches are used in specific clinical situations. All three approaches include mastoidectomy, facial nerve transposition, and conductive hearing deficit due to obliteration of external and middle ear. Type-A approach is employed for management of paragangliomas, neuromas, and meningiomas of the jugular foramen. Radical mastoidectomy and cervical dissection are performed, the facial nerve is anteriorly transposed. This approach provides access to the infratemporal fossa and jugular foramen and to the vertical portion of the internal carotid artery (ICA) . Jugular foramen paragangliomas with larger intradural extensions (2 cm or more) are resected in two stages. Type-B approach is used to remove lesions of the petrous apex and mid-clivus (petrous apex cholesteatomas, chordomas, cholesteatomas, and some meningiomas). This approach allows exposure of the horizontal ICA, petrous apex, superior infratemporal fossa, and foramen ovale. Type-C approach is used to resect nasopharyngeal angiofibromas and some nasopharyngeal carcinomas.
Our strategy of surgical treatment of jugular foramen tumors differs from that proposed by Fisch because according to our experience a multidisciplinary team composed by neurosurgeons, ENT-surgeons, otologists, neuroradiologists, endovascular surgeons, and intensivists offer the patients the best chance of radical removal in one surgery with functional preservation (Fig. 9.1). In our opinion this multidisciplinary team should be prepared to manage all possible surgical difficulties and complications as: involvement of ICA requiring reconstruction of the vessel, high- and low-flow bypasses between the ICA and the middle cerebral artery, reconstruction of affected cranial nerves, reconstruction of larger skull base defects caused by tumor infiltration and extensive bone removal at skull base, and tumor dissection from brainstem and intracranial vessels [2–4]. Glomus tympanicum develops inside the middle ear without invasion of the jugular foramen. Small glomus tympanicum on promontory is removed through a transcanal approach. Larger tumors are removed through an incision behind the ear, drilling the facial recess and mastoid to approach the middle ear. As these tumors do not involve the jugular foramen and the posterior fossa, the surgical approaches to these tumors will not be discussed in this chapter.
Fig. 9.1
Jugular foramen tumors originate in the skull base and may invade the ear, neck, and intradural regions
According to the extension of the tumor two main surgical approaches have been used to treat the jugular foramen tumors in our series [5–8]. (a) The modified retrosigmoid approach indicated when the tumor is predominantly intradural without extensions to the cervical region without involvement of the ICA. Tumor infiltration or extension within the jugular foramen, mastoid, and middle ear can be removed by drilling the posterior wall of the jugular foramen and mastoid exposing the sigmoid sinus, retrofacial mastoid cells, semicircular channels, and hypotympanum. Meningiomas, schwannomas, chordomas, chondrosarcomas, and some paragangliomas are the most frequent jugular foramen tumors removed through this approach. (b) The cranio-cervical approach : indicated when the tumor extends into the cervical region, retropharyngeal space, involves the clivus, the ICA, the vertebral artery, the jugular bulb, and the internal jugular vein (IJV) . Paragangliomas, schwannomas, and large meningiomas are the most frequent lesions requiring a cranio-cervical approach.
Retrosigmoid Approach
The patient may be placed in semi-sitting position (preference at University of Tübingen) (Fig. 9.2), dorsal decubitus or “mastoid position” (preference at the Neurological Institute of Curitiba) (Fig. 9.3), or “park-bench position .” The anesthesiologist should check the lateral neck on both sides for jugular vein compression to avoid air embolism. In dorsal decubitus the head is rotated about 30° to the opposite side with light lateral extension. A pillow is placed under the shoulder to avoid excessive rotation of the head and compression of vertebral artery at the cranio-cervical junction. The opposite IJV must be checked to assure that it is not compressed (Fig. 9.4).
Fig. 9.2
(a) Patient in semi-sitting position . The legs are above the level of heart to avoid air embolism. (b) Sitting position, the legs are below the heart level
Fig. 9.3
Patient in dorsal position with the head rotated to the opposite side
Fig. 9.4
Patient in dorsal position the head is slightly extended. A pillow is placed under the shoulder to avoid excessive rotation of the head
In semi-sitting position the legs are placed above the level of the heart with the knees slightly flexed (Fig. 9.5). The head is rotated 30° toward the affected side, hyperextended, and flexed. Bilateral SEPs are continuously monitored during positioning. In order to check the occurrence of air embolus, transesophageal echocardiography or precordial doppler is used. Neurophysiological monitoring of cranial nerves V, VI, VII, VIII, IX, X, XI, and XII is performed (Figs. 9.6, 9.7, and 9.8).
Fig. 9.5
Patient in semi-sitting position . (a) Skin incision. (b) Incision may be extended to the temporal and cervical regions
Fig. 9.6
Transesophageal echocardiography and precordial doppler are used to check the occurrence of air embolus
Fig. 9.7
Neurophysiological monitoring of cranial nerves V, VII, and VIII
Fig. 9.8
Neurophysiological monitoring of lower cranial nerves
Skin incision (straight or slightly curved) starts in the retromastoid region about 5 cm behind the external auditory canal and extends 2 cm behind the mastoid tip, ending in the upper neck (Fig. 9.9). The inferior extension of the skin incision depends on the tumor extension. Scalp is elevated with the periosteum. Fascia and muscles are cut straight down exposing the occipital bone, the asterium, and the retromastoid region and held with a self-retaining retractor (Fig. 9.10). With the aid of neuronavigation a burr hole is performed at the transversus and sigmoid sinuses junction (usually at the asterion ) (Fig. 9.11). A 4 cm diameter craniotomy is cut (Fig. 9.12). With a high-speed diamond drill the transverse and sigmoid sinuses are exposed. Part of squamous occipital bone is removed with rongeurs until the jugular bulb. Craniectomy is also an option in cases of dura adherence to the occipital bone (elderly patients). The mastoid emissary vein is coagulated and cut. In semi-sitting position care should be taken to avoid air embolism when the sinuses and the emissary veins are exposed. Jugular vein compression in the neck or Valsalva maneuver helps to identify venous bleeding. Small sigmoid sinus lacerations are repaired either with sutures or small pieces of muscle fascia and fibrin glue (Fig. 9.13). Care should be taken to not occlude the sinus by packing lacerations with hemostatic material or muscle. The opened mastoid cells are packed with bone wax or muscle pieces and fibrin glue. Mannitol is administered intravenously before opening of the dura mater. Under the magnification of the operation microscope, the dura mater is incised in a C-shaped fashion, parallel to sigmoid sinus (Fig. 9.14). The lateral aspect of cerebellum is slightly retracted and the cerebellomedullary cistern is opened relaxing the posterior fossa. This maneuver is carried out with cotton strips or a rubber strip to protect the cerebellum against lacerations. Brain retractor is used to protect rather than retract the cerebellum. The lower cranial nerves are mostly involved or infiltrated by the tumor. The VI, VII, and VIII cranial nerves, the PICA, the vertebral artery, and the brainstem are usually attached to the tumor capsule (Fig. 9.15). In cases of meningiomas, paragangliomas, and aggressive tumors, the cranial nerves IX, X, and XI may be embedded or even infiltrated. The posterior wall or the jugular foramen is exposed (Fig. 9.16). A C-shaped dura incision based on the posterior lip of the jugular foramen is carried out and the foramen is opened with high-speed diamond drill (Fig. 9.17). Very careful dissection of the nerves within the jugular foramen is performed, under monitoring, to avoid damage to these structures and to the jugular bulb. The use of endoscope is helpful to dissect the tumor from cranial nerves within the jugular foramen (Fig. 9.18). If these nerves are infiltrated and the patient preoperatively has no deficit, radical resection is not attempted. In these cases, benign lesions are treated postoperatively with radiosurgery only if growth of the tumor rest is observed. Solid tumors are initially intracapsular enucleated. Gently dissection of the tumor capsule shows the arachnoid interface between the tumor and the surrounding structures. After coagulation of the dural attachments, intracapsular piecemeal resection is carried out. In contrast to solid tumors, cystic schwannomas have strong adherence to cranial nerves and the arachnoid interface should be first identified and dissected, avoiding opening the cyst [9–11]. Meticulous sharp dissection of the arachnoid plane followed by evacuation of the cyst will permit removal of the cyst wall from the surrounding structures (Fig. 9.19). After tumor removal, watertight continuous suture of dura mater is performed. The bone flap is replaced and fixed with mini-plates or cranioplasty with methyl methacrylate is performed. The wound is sutured in usual fashion and no drain is used.
Fig. 9.9
Skin incision
Fig. 9.10
Identification of the asterium
Fig. 9.11
Identification of sigmoid and tranverse sinuses junction with neuronavigation
Fig. 9.12
Retrosigmoid craniotomy
Fig. 9.13
Drawings showing management of emissary vein lesion (a), small (b) and large injury of the sigmoid sinus
Fig. 9.14
Opening of the dura mater parallel to the sigmoid sinus
Fig. 9.15
Large jugular foramen meningioma . Dissection of lower cranial nerves from tumor capsule
Fig. 9.16
Anatomical specimen showing the lower cranial nerves after opening the JF (arrows) through a retrosigmoid approach
Fig. 9.17
(a) JF meningioma (TU). (b) Intradural drilling of jugular foramen (arrow). (c) Tumor dissection from lower cranial nerves. (d) Total tumor removal
Fig. 9.18
Endoscopic assisted microsurgical removal of JF meningioma
Fig. 9.19
Large cystic JF schwannoma . Transcerebellar evacuation of the cyst (arrows)
Cranio-cervical Approach
Position of Patient and Skin Incision
The positioning of the patient is discussed with the anesthesiologist. Intermittent compression of the lower limbs to prevent deep vein thrombosis is used for patient at risk of this complication. A nasoenteral tube is inserted. For the cranio-cervical approach the patient is placed in dorsal position with the head fixed in a cranial clamp (Mayfield) slightly extended and rotated between 30° and 45° to the contralateral side (Fig. 9.20). The ipsilateral shoulder is elevated and the opposite IJV must be free (Fig. 9.21). All body contact areas must be checked due to the long duration of the surgery. A nasogastric tube is inserted. Electrophysiological monitoring of cranial nerves V, VI, VII, VIII, IX, X, XI, and XII, as well as bilateral somatosensory evoked responses (SAEPs) , are performed according to the extension of the tumor. All parameters for neuronavigation are checked.
Fig. 9.20
Patient’s position for cranio-cervical approach to the JF
Fig. 9.21
Neuronavigation is used to define tumor margins
A C-shaped skin incision starts in the temporal region about 5 cm superior to the zygomatic arch circumscribes the ear and the mandible angle, and continues in a cervical fold over the border of the sternocleidomastoid muscle (SCM) reaching the midline (Fig. 9.22). The great auricular nerve is identified and dissected (Fig. 9.23). This nerve may be used as graft for reconstruction of the facial nerve in those cases when the VII nerve is infiltrated by the tumor and must be resected. The skin flap is rotated anteriorly exposing the temporal muscle fascia, the external auditory canal, the mastoid tip, and the anterior border of the SCM muscle (Fig. 9.24). If the tumor invades the middle ear, destroying the ossicular chain extending to the external auditory canal, the canal is cut at the osseocartilaginous junction (Fig. 9.25). To avoid postoperative CSF leak the external auditory meatus is sutured in two layers (Fig. 9.25).
Fig. 9.22
C-shaped skin incision for cranio-cervical approach
Fig. 9.23
Rotation of skin flap and dissection of great auricular nerve (GAN)
Fig. 9.24
Anatomic specimen showing the anterior border of sternocleidomastoid muscle (SCM) , external auditory canal (EAC), temporal muscle fascia (TMF), great auricular nerve (GAN)
Fig. 9.25
The external auditory canal (EAC) is cut at the osseocartilaginous junction . The external auditory meatus is sutured in two layers (arrow)