Cystitis

Uncomplicated cystitis: women who are not pregnant, without underlying structural or neurologic disease.

Complicated cystitis: upper tract infection or any urinary tract infection in men or pregnant women or urinary tract infection with underlying structural or neurologic disease.

Pain on urination

Urgency

Increased frequency

Change in urine color or odor

Suprapubic pain

Uncomplicated:

Trimethoprim/sulfamethoxazole 160/800 mg 2 p.o. ×1

Ciprofloxacin 250 mg to 500 mg p.o. every 12 h ×3 d

Ofloxacin 200 mg p.o. every 12 h ×3 d

Complicated:

Administer antibiotic regimens above ×10-14 d

Urethritis

Pain on urination

Urgency

Increased frequency

Change in urine color or odor

Suprapubic pain

Urethral discharge

Treat for both Neisseria and Chlamydia

Neisseria: ceftriaxone 125 mg IM ×1 Cefixime 400 mg p.o. ×1

Chlamydia: doxycycline 100 mg p.o. every 12 h ×7d

Azithromycin 1 g p.o. ×1

Prostatitis

Pain on urination

Urgency

Increased frequency

Change in urine color or odor

Suprapubic pain

Sensation of incomplete emptying

Weak stream

Acute

Trimethoprim/sulfamethoxazole 160/800 mg p.o. every 12 h ×21 d

Ciprofloxacin 750 mg p.o. every 12 h ×21 d

Ofloxacin 200-300 mg p.o. every 12 h ×21 d

Chronic

Trimethoprim/sulfamethoxazole 160/800 mg p.o. every 12 h ×1-3 months

Ciprofloxacin 250-500 mg p.o. every 12 h ×1-3 months

Ofloxacin 200-400 mg p.o. every 12 h ×1-3 months

Pyelonephritis

Fever

Shaking chills

Flank or back pain

Nausea

Vomiting

Diarrhea

Acute

Trimethoprim/sulfamethoxazole 160/800 mg p.o. every 12 h ×21 d

Ciprofloxacin 750 mg p.o. every 12 h ×21 d

Ofloxacin 200-300 mg every 12 h ×21 d

Complicated cases may require IV antibiotics