Cerebral Veins and Sinuses



Cerebral Veins and Sinuses





Occlusion of cerebral veins and sinuses associated with various disorders (Table 47.1). Lateral, cavernous, superior sagittal sinuses most frequently affected.


Lateral Sinus Thrombosis

Usually due to otitis media, mastoiditis. Infants, children most commonly affected. Septicemia in 50%.


Symptoms and Signs

Fever, headache, nausea, vomiting (increased intracranial pressure). Papilledema (usually bilateral) in 50%. Additionally: drowsiness, coma, seizures, cranial nerve signs; systemic signs of septicemia.



  • Gradenigo syndrome: lateral rectus weakness (sixth nerve palsy), facial pain (fifth nerve damage).


Investigations

Blood: leukocytosis; cultures positive in 50%. CSF: increased pressure, turbid appearance, leukocytosis.

CT, MRI: clot may appear as linear density (“cord sign”). Magnetic resonance venography (MRV): focal narrowing or nonvisualization of involved portion of sinus.


Treatment

Antibiotics for underlying otitis media; surgical drainage; jugular vein ligation. Nonseptic patients: thrombolytic therapy may suffice.









Table 47.1 Disorders Associated with Cerebral Vein and Sinus Occlusion






































Primary idiopathic thrombosis
Secondary thrombosis
 Pregnancy
 Postpartum
 Oral contraceptive pill
 Trauma: after open or closed head injury
 Tumors
  Meningioma
  Metastatic tumors
Malnutrition and dehydration (marantic thrombosis)
Infection: sinus thrombophlebitis, bacterial, fungal
Hematologic disorders
 Polycythemia
 Cryofibrinogenemia
 Sickle-cell anemia
 Leukemia
 Disseminated intravascular coagulation and other coagulopathy
Behçet syndrome

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Jul 27, 2016 | Posted by in NEUROLOGY | Comments Off on Cerebral Veins and Sinuses

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