Differential Diagnosis of Stroke
Clinical Features of Stroke Subtypes
Distinction essential in choice of acute treatment of stroke: in first 3 hours, thrombolysis may be indicated in acute infarct; contraindicated in acute hemorrhage. Subsequently, anticoagulation may be indicated for cerebral embolism.
The following clinical features suggest specific stroke subtype but overlap is evident.
Infarction
Cerebral embolism. Occlusion usually in distal vessels (e.g., cortex). Sudden onset, isolated cortical signs (aphasia, hemianopia).
Thrombosis. Distal vessel occlusion: often indistinguishable from embolism. Deep penetrating vessel: elementary deficit (weakness, sensory loss, ataxia), often affecting large body regions (arm, face, leg simultaneously), sparing cortical function (language, spatial attention. Proximal occlusion (e.g., MCA stem): severe deficits of entire half of body, often with impaired alertness.
Hemorrhage
Characteristically smooth onset. May be indistinguishable from infarction when onset is rapid. CT necessary to rule out hemorrhage.
Epidural hematoma: fracture line passing through groove of middle meningeal artery may be visible on CT (bone windows). Even severe syndrome may be reversible by surgical evacuation.Stay updated, free articles. Join our Telegram channel
Full access? Get Clinical Tree