Epilepsy I: Diagnosis

Epilepsy I


Diagnosis


A seizure is a paroxysmal neurological event caused by the abnormal discharge of neurones. Epilepsy is defined as a tendency to recurrent seizures, that is two or more seizures. Epilepsy is not a single disease but it is a symptom of congenital or acquired CNS disease in the same way as weakness is a symptom in a range of different disorders. Different types of epilepsy can be classified according to different features, including seizure type, age of onset, prognosis and cause, and are more appropriately called the epilepsies.


The epilepsies are the most common serious neurological diseases; 5% of the population will experience an epileptic seizure at some point in their life. Their prevalence is 0.5%; 370 000 people in the UK are affected. Males and females are similarly affected. Peaks of onset occur in childhood/adolescence in relation to congenital causes and in the elderly are presumed to be secondary to cerebrovascular and degenerative diseases.


Seizures cause unpredictable loss of control, which makes epilepsy one of the most stigmatizing and socially disabling of all diseases, adversely affecting many aspects of life, such as increasing divorce rates, and adversely affecting employment opportunities. Epilepsy is associated with depression and psychiatric illness.





Classification of seizures and epilepsy syndromes


Much of the confusion about the classifications in epilepsy arise because of a failure to appreciate that there are two interrelated classifications: a classification of seizure type (Fig. 1) and a classification of epilepsy syndromes (Table 1). Patients may have more than one type of seizure. The epilepsy syndrome includes diagnosis of seizure type and additional information, mostly relating to aetiology, including age, EEG and neuroimaging results. Where possible, patients’ epilepsy should be classified by epilepsy syndrome rather than seizure type, which takes into account these other factors. The old terms ‘petit mal’ and ‘grand mal’ do not fit easily into this classification and should not be used.




There are three broad categories of epilepsy syndromes:





Patients who have had only a few attacks may not be classifiable into an epileptic syndrome.

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Jun 10, 2016 | Posted by in NEUROLOGY | Comments Off on Epilepsy I: Diagnosis

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