70 Other Peripheral Motor Hyperactivity Syndromes H. Royden Jones, Jr. Isaac (Merten) Syndrome/Quantal Squander, Neuromyotonia This is another hyperkinetic presumed peripheral nerve hyperexcitability syndrome that occurs even more rarely than the stiff person syndrome. As noted above, there are a number of synonyms. It is a very unusual neurologic disorder also characterized by the continuous firing of peripheral nerves, and thus muscle fibers. It is much more subtle in its presentation. Typically the age of onset is in the teenage years, but it may be seen in adulthood. This appears to be autoimmune in origin (anti–potassium channel antibodies are positive in some patients.) This is a nonspecific finding per se as these antibodies may be found in a variety of neurologic syndromes. Here the patient first notes what appears to be an almost continuous firing of groups of muscle fibers usually appearing to mimic fasciculations. These occur concomitantly in both agonists and antagonists. The patient often notes a sense of fatigue. Usually there are no significant associated muscle spasms, cramping, or pain; however, in some instances such may occur. The patient may note a degree of weakness because of the inconsistent firing of opposing muscle groups, leading to ineffective mechanical function. Some patients have excessive sweating. Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: Wilson Disease Cranial Nerve V Other Neuromuscular Transmission Disorders Coma, Vegetative State, Brain Death, and Increased Intracranial Pressure Lumbar Radiculopathy Subarachnoid Hemorrhage Stay updated, free articles. Join our Telegram channel Join Tags: Netters Neurology Jun 4, 2016 | Posted by admin in NEUROLOGY | Comments Off on Other Peripheral Motor Hyperactivity Syndromes Full access? Get Clinical Tree
70 Other Peripheral Motor Hyperactivity Syndromes H. Royden Jones, Jr. Isaac (Merten) Syndrome/Quantal Squander, Neuromyotonia This is another hyperkinetic presumed peripheral nerve hyperexcitability syndrome that occurs even more rarely than the stiff person syndrome. As noted above, there are a number of synonyms. It is a very unusual neurologic disorder also characterized by the continuous firing of peripheral nerves, and thus muscle fibers. It is much more subtle in its presentation. Typically the age of onset is in the teenage years, but it may be seen in adulthood. This appears to be autoimmune in origin (anti–potassium channel antibodies are positive in some patients.) This is a nonspecific finding per se as these antibodies may be found in a variety of neurologic syndromes. Here the patient first notes what appears to be an almost continuous firing of groups of muscle fibers usually appearing to mimic fasciculations. These occur concomitantly in both agonists and antagonists. The patient often notes a sense of fatigue. Usually there are no significant associated muscle spasms, cramping, or pain; however, in some instances such may occur. The patient may note a degree of weakness because of the inconsistent firing of opposing muscle groups, leading to ineffective mechanical function. Some patients have excessive sweating. Only gold members can continue reading. Log In or Register to continue Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window) Related Related posts: Wilson Disease Cranial Nerve V Other Neuromuscular Transmission Disorders Coma, Vegetative State, Brain Death, and Increased Intracranial Pressure Lumbar Radiculopathy Subarachnoid Hemorrhage Stay updated, free articles. Join our Telegram channel Join Tags: Netters Neurology Jun 4, 2016 | Posted by admin in NEUROLOGY | Comments Off on Other Peripheral Motor Hyperactivity Syndromes Full access? Get Clinical Tree
