Fig. 50.1
Propofol effects on MRI. Axial FLAIR images (a–d) show diffuse high signal within the subarachnoid spaces of the sulci and basal cisterns
50.4 Differential Diagnosis
Subarachnoid FLAIR hyperintensity has been observed in a variety of other conditions, including meningitis, leptomeningeal carcinomatosis, hemorrhage, leptomeningeal melanosis, stroke, and supplemental oxygen administration (refer to Chap. 35).
Suggested Reading
Fillipi CG, Ulug AM, Lin D, Heir LA, Zimmerman RD. Hyperintense signal abnormality in subarachnoid spaces and basal cisterns on MR images of children anesthetized with propofol: new fluid-attenuated inversion recovery finding. AJNR Am J Neuroradiol. 2001;22:394–9.
Fugii J, Miyachi S, Matsubara N, Kinkori T, Takebayashi S, Izumi T, Ohshima T, Tsurumi A, Hososhima O, Wakabayashi T, Yoshida J. Selective propofol injection into the M1 segment of the middle cerebral artery (MCA Wada test) reduces adverse effects and enhances the reliability of the Wada test for determining speech dominance. World Neurosurg. 2011;75(3–4):503–8.CrossRef
Gili T, Saxena N, Diukova A, Murphy K, Hall JE, Wise RG. The thalamus and brainstem act as key hubs in alterations of human brain network connectivity induced by mild propofol sedation. J Neurosci. 2013;33(9):4024–31.CrossRefPubMedCentralPubMed