Scalp Mass
Miral D. Jhaveri, MD
DIFFERENTIAL DIAGNOSIS
Common
Subgaleal Hematoma
Foreign Body
Lipoma
Sebaceous Cyst
Metastases, Skull
Less Common
Dermoid Cyst
Epidermal Inclusion Cyst
Basal Cell Carcinoma
Squamous Cell Carcinoma
Edema/Anasarca
Hemangioma
Venolymphatic Malformations
Neurofibromatosis Type 1
Lymphoma
Langerhans Cell Histiocytosis
Rare but Important
Sinus Pericranii
Atretic Cephalocele
Sarcoma (Kaposi, etc.)
ESSENTIAL INFORMATION
Key Differential Diagnosis Issues
Density of mass on NECT helpful
Hyperdense: Acute subgaleal hematoma
Fat density: Lipoma, dermoid cyst
Fluid density: Sebaceous cyst, epidermal inclusion cyst
Enhancing mass + skull changes: Metastasis, squamous/basal cell carcinoma
Helpful Clues for Common Diagnoses
Subgaleal Hematoma
Not confined by cranial sutures
Traumatic, post-surgical
Lipoma
Well-defined fat density/signal intensity
Sebaceous Cyst
Often fluid density/intensity
Metastases, Skull
Destructive skull lesion with associated scalp mass
Helpful Clues for Less Common Diagnoses
Dermoid Cyst
Midline, frontotemporal > parietal
Fat density, signal
Epidermal Inclusion Cyst
Location similar to dermoid cyst
Fluid density, signal
Venolymphatic Malformations
Multiseptate cystic masses ± intracystic hemorrhage/fluid levels
± Phleboliths (signal voids)
Neurofibromatosis Type 1
Plexiform neurofibroma unencapsulated, infiltrating
Langerhans Cell Histiocytosis
“Punched-out” skull lesion without reactive sclerosis
± Enhancing soft tissue massStay updated, free articles. Join our Telegram channel
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