Fig. 9.1
Cognitive behavioral therapy for insomnia improves sleep and decreases pain in older adults with comorbid insomnia and osteoarthritis. J Clin Sleep Med. 2009;5(4):355–62 (from Vitiello MV, Rybarczyk B, Von Korff M, Stepanski EJ)
Management of Sleep in Patients with Arthritis
Since many patients with arthritis report sleep disturbances (Louie et al., 2011), inquiring about sleep problems is important for identifying and subsequently treating sleep disturbances that could, in turn, improve other arthritis-related symptoms such as pain, fatigue, depression, and disability. As compared to pharmacotherapy, CBT-I is often preferred by patients (Morin, Gaulier, Barry, & Kowatch, 1992) and has been shown to have short-term and long-term efficacy (Irwin, Cole, & Nicassio, 2006). Preliminary evidence suggests that CBT-I can improve sleep quality and pain in those with OA (Vitiello et al., 2009, 2013, 2014). Given that arthritis can cause activity limitations and restrict patients’ ability to get around outside their homes (Verbrugge & Juarez, 2006), patients may be reluctant to undergo CBT-I which requires 6–8 weekly face-to-face individual sessions. Thus, alternative nonpharmacological insomnia treatment options that are less intensive may be more appealing to patients and have more widespread dissemination.
Brief behavioral treatment for insomnia (BBTI) is a manualized, behavioral treatment program involving two in-person sessions and two telephone booster sessions. BBTI can be delivered by healthcare professionals without specialized training. BBTI emphasizes the behavioral components of CBT-I, in particular sleep restriction and stimulus control, by modifying waking behaviors to increase and regulate the duration of wakefulness to increase homeostatic sleep drive and provide an individualized sleep and wake prescription to optimize the circadian sleep drive (Troxel, Germain, & Buysse, 2012). The intervention provides patients with four main “rules” for better sleep (Table 9.1): (1) reduce time in bed, (2) get up at the same time of day every day, regardless of sleep duration, (3) do not go to bed unless sleepy, and (4) do not stay in bed unless asleep. BBTI has been shown to have short-term efficacy in a sample of 79 older adults with insomnia and comorbid conditions (Buysse et al., 2011). In brief, participants were randomly assigned to either BBTI or an information control consisting of printed sleep education materials. As compared to the IC group, patients receiving BBTI reported significant improvements in sleep diary- and actigraphy-measured sleep outcomes and had greater rates of treatment response (defined as PSQI score of ≥3 points or change in sleep diary sleep efficiency of ≥10 %) at posttreatment. Of the 25 patients with a favorable treatment response, 64 % no longer met insomnia criteria at 6-month follow-up.
Table 9.1
Brief behavioral sleep for insomnia (BBTI) : four rules for better sleep
Rules | Description |
---|---|
1. Reduce time in bed | Decrease the amount of time awake in bed to habitual sleep time (based on sleep diary) plus 30 min |
Cutting down time in bed will increase how long spent awake and will lead to quick, deeper, more solid sleep | |
2. Get up the same time every day of the week, no matter how poorly you slept the night before | Getting up at the same time helps set the biological clock and regulates exposure to morning light, also an important cue for setting the biological clock |
3. Don’t go to bed unless you are sleepy | This helps to increase sleep drive by keeping you awake longer |
Going to bed when you’re not sleepy can lead to frustration | |
4. Don’t stay in bed unless you are asleep | If awake for more than 30 min, get out of bed and engage an activity that is not overly stimulating in a low-light setting. Once you are sleepy, return to bed |
This helps the brain develop a learned association between bed and sleep | |
Have activities planned ahead of time that you can do when you get out of bed |
Only one study has directly tested the effects of a sleep intervention in patients with arthritis (Vitiello et al., 2013, 2014). The favorable effects of CBTI on sleep and pain in this study warrant future research to explore cognitive and behavioral treatments for insomnia in patients with arthritis. BBTI may be a viable treatment option due to its brief design requiring limited in-person sessions and the advantage of treatment delivery by nurses and other professionals with limited experience in sleep medicine or behavioral therapies.
References
Abad, V. C., Sarinas, P. S., & Guilleminault, C. (2008). Sleep and rheumatologic disorders. Sleep Medicine Reviews, 12(3), 211–228.PubMed
Achterberg, J., McGraw, P., & Lawlis, G. F. (1981). Rheumatoid arthritis: A study of relaxation and temperature biofeedback training as an adjunctive therapy. Biofeedback and Self Regulation, 6(2), 207–223.PubMed
Afonso, R. F., Hachul, H., Kozasa, E. H., de Souza Oliveira, D., Goto, V., Rodrigues, D., Tufik, S., & Leite, J.R. (2012). Yoga decreases insomnia in postmenopausal women: A randomized clinical trial. Menopause, 19(2), 186–193.
Baglioni, C., Battagliese, G., Feige, B., Spiegelhalder, K., Nissen, C., Voderholzer, U., Lombardo, C., & Riemann, D. (2011). Insomnia as a predictor of depression: A meta-analytic evaluation of longitudinal epidemiological studies. Journal of Affective Disorders, 135(1), 10–19.
Belza, B. L., Henke, C. J., Yelin, E. H., Epstein, W. V., & Gilliss, C. L. (1993). Correlates of fatigue in older adults with rheumatoid arthritis. Nursing Research, 42(2), 93–99.PubMed
Budhiraja, R., Roth, T., Hudgel, D. W., Budhiraja, P., & Drake, C. L. (2011). Prevalence and polysomnographic correlates of insomnia comorbid with medical disorders. Sleep, 34(7), 859.PubMedCentralPubMed
Buysse, D. J., Ancoli-lsrael, S., Edinger, J. D., Lichstein, K. L., & Morin, C. M. (2006). Recommendations for a standard research assessment of insomnia. Sleep, 23(9), 1155–1173.
Buysse, D. J., Germain, A., Moul, D. E., Franzen, P. L., Brar, L. K., Fletcher, M. E., Begley, A., Houck, P.R., Mazumdar, S., Reynolds, C.F., & Monk, T.H. (2011). Efficacy of brief behavioral treatment for chronic insomnia in older adults. Archives of Internal Medicine, 171(10), 887–895.
Buysse, D. J., Reynolds, C. F., III, Monk, T. H., Berman, S. R., & Kupfer, D. J. (1989). The Pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research. Psychiatry Research, 28(2), 193–213.PubMed
Cakirbay, H., Bilici, M., Kavakcio, C. A., Guler, M., & Tan, Ü. (2004). Sleep quality and immune functions in rheumatoid arthritis patients with and without major depression. The International Journal of Neuroscience, 114(2), 245–256.PubMed
Chandrasekhara, P. K. S., Jayachandran, N. V., Rajasekhar, L., Thomas, J., & Narsimulu, G. (2009). The prevalence and associations of sleep disturbances in patients with systemic lupus erythematosus. Modern Rheumatology, 19(4), 407–415.PubMed
Costa, D. D., Bernatsky, S., Dritsa, M., Clarke, A. E., Dasgupta, K., Keshani, A., & Pineau, C. (2005). Determinants of sleep quality in women with systemic lupus erythematosus. Arthritis Care & Research, 53(2), 272–278.
Crosby, L. J. (1988). EEG sleep variables of rheumatoid arthritis patients. Arthritis and Rheumatism, 1(4), 198–204.
Dixon, K. E., Keefe, F. J., Scipio, C. D., Perri, L. M., & Abernethy, A. P. (2007). Psychological interventions for arthritis pain management in adults: A meta-analysis. Health Psychology, 26(3), 241–250.PubMed
Drewes, A. M., Bjerregård, K., Taagholt, S. J., Svendsen, L., & Nielsen, K. D. (1998). Zopiclone as night medication in rheumatoid arthritis. Scandinavian Journal of Rheumatology, 27(3), 180–187.PubMed
Drewes, A. M., Nielsen, K. D., Hansen, B., Taagholt, S. J., Bjerregård, K., & Svendsen, L. (2000). A longitudinal study of clinical symptoms and sleep parameters in rheumatoid arthritis. Rheumatology (Oxford), 39(11), 1287–1289.
Drewes, A. M., Svendsen, L., Nielsen, K. D., Taagholt, S. J., & Bjerregård, K. (1994). Quantification of alpha-EEG activity during sleep in fibromyalgia: A study based on ambulatory sleep monitoring. Journal of Musculoskelatal Pain, 2(4), 33–53.
Drewes, A. M., Svendsen, L., Taagholt, S. J., Bjerregård, K., Nielsen, K. D., & Hansen, B. (1998). Sleep in rheumatoid arthritis: A comparison with healthy subjects and studies of sleep/wake interactions. Rheumatology (Oxford), 37(1), 71–81.
Driver, H. S., & Taylor, S. R. (2000). Exercise and sleep. Sleep Medicine Reviews, 4(4), 387–402.PubMed
Durcan, L., Wilson, F., & Cunnane, G. (2014). The effect of exercise on sleep and fatigue in rheumatoid arthritis: A randomized controlled study. The Journal of Rheumatology, 41(10), 1966–1973.PubMed
Edinger, J. D., Fins, A. I., Glenn, D. M., Sullivan, R. J., Jr., Bastian, L. A., Marsh, G. R., Dailey, D., Hope, V.T., Young, M., Shaw, E. & Vasilas, D. (2000). Insomnia and the eye of the beholder: Are there clinical markers of objective sleep disturbances among adults with and without insomnia complaints? Journal of Consulting and Clinical Psychology, 68(4), 586–593.
Edinger, J. D., & Means, M. K. (2005). Cognitive-behavioral therapy for primary insomnia. Clinical Psychology Review, 25(5), 539–558.PubMed
Ferguson, S. J., & Cotton, S. (1996). Broken sleep, pain, disability, social activity, and depressive symptoms in rheumatoid arthritis. Australian Journal of Psychology, 48(1), 9–14.
Fragiadaki, K., Tektonidou, M. G., Konsta, M., Chrousos, G. P., & Sfikakis, P. P. (2012). Sleep disturbances and interleukin 6 receptor inhibition in rheumatoid arthritis. The Journal of Rheumatology, 39(1), 60–62.PubMed