Spirochete Infections: Lyme Disease



Spirochete Infections: Lyme Disease






Epidemiology

Borrelia burgdorferi spirochete transmitted to humans by ixodid ticks (which in the United States infest deer, mice). Usually in wooded areas of United States; peak disease incidence from May to September.


Symptoms and Signs


First Stage

Erythema chronicus migrans (ECM): migrating erythematous circular rash, with appearance of “bull’s-eye,” or “target,” 3 to 30 days after tick bite. Headache, myalgia, stiff neck, cranial nerve palsies (almost always seventh nerve) may occur. CSF usually normal.


Second Stage

Several weeks after onset of ECM.

Heart conduction defects; meningism, often afebrile; radiculitis (multiple or isolated, root pain or focal weakness). Seventh cranial nerve frequently involved, usually bilateral. Polyneuritis or mononeuritis multiplex. Decreased concentration, irritability, emotional lability, memory, sleep disorders.

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Jul 27, 2016 | Posted by in NEUROLOGY | Comments Off on Spirochete Infections: Lyme Disease

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