193 | Stereotactic Radiosurgery Planning |
♦ Stereotactic Imaging
Basic Principles
- The first step in a planning radiosurgical procedure is to obtain adequate high quality stereotactic images.
- The fiducial box is placed on the base ring of the stereotactic frame, then the head is secured in a special holder for the time of imaging.
- Focus images on the region of interest (no need to image the whole head, except for brain metastases).
- Some technologies require whole imaging to calculate beam attenuation.
- Verify that fiducials are adequately seen in each image series (required to later define stereotactic space in the planning computer).
Magnetic Resonance Imaging
- Imaging modality of choice for most cases because of optimal contrast definition between normal and abnormal tissues, and high spatial resolution
- May be subject to artifact causing distortion of stereotactic coordinates, therefore the fiducials must be measured and compared between each side to ensure image accuracy
- Volumetric acquisition of images is optimal (do not skip any image signal between slices)
- Suggested imaging sequences
- Acoustic neuromas
- One- to 1.5-mm thick contrast-enhanced spoiled-gradient recalled acquisition in steady state (SPGR) images
- One-millimeter thick T2-weighted imaging (to help define the intracanalicular portion and inner ear anatomy)
- One- to 1.5-mm thick contrast-enhanced spoiled-gradient recalled acquisition in steady state (SPGR) images
- Meningiomas
- One- to 1.5-mm thick contrast-enhanced SPGR images
- Pituitary adenomas
- One- to 1.5-mm thick contrast-enhanced SPGR images (with or without fat suppression)
- Arteriovenous malformations
- One- to 2-mm thick contrast-enhanced SPGR images
- Brain metastases
- Two-millimeter thick SPGR sequence with double-dose contrast covering the whole head
- Trigeminal neuralgia
- One-millimeter thick contrast-enhanced SPGR sequence
- T2-weighted images may assist nerve definition (especially in cases of previous surgical management)
- One-millimeter thick contrast-enhanced SPGR sequence
- Acoustic neuromas
- Generally used only if there is a contraindication to magnetic resonance imaging (MRI)
- May be helpful to better define bony lesions
- Artifacts from pins may obscure target lesion
Digital Subtraction Angiography
- Used in conjunction with MRI or computed tomography for arteriovenous malformations (AVM) radiosurgery
- The AVM and regional arteries and veins need to be imaged.
- Must verify that images include all nine fiducial markers
♦ Radiosurgery Planning
Patient File Creation
- Enter patient demographic and clinical information.
- The skull and frame measurements are entered and checked for accuracy.
Setting Up Images in Planning Computer
- The stereotactic images are imported via Ethernet or scanned into the planning computer.
- Confirm images are from the right patient.
- The stereotactic space is defined for each set of images.
- The quality of images is rechecked (fiducials) because of possible distortion during image transfer.
Target Outlining
- Useful when the target volume is not clearly identified
- Helpful to assess conformality of the radiosurgery volume
Dose Planning
- Set one or more dose matrices for calculation.
- Need to center the matrix over lesion to be irradiated and have its size match the lesion to optimize the accuracy of dose calculations
- Isocenter placement
- Conformality is the key: precisely match the isodose line used (often the 50% isodose line for Gamma Knife radiosurgery) to the lesion’s shape.
- Start either at the center of the lesion and build around it while going toward the edges or from one border to another.
- Use larger isocenters first then complete with smaller ones.
- Try to minimize the number of different collimator sizes used.
- Software-assisted planning (inverse planning) is possible if the target was outlined previously.
- Conformality is the key: precisely match the isodose line used (often the 50% isodose line for Gamma Knife radiosurgery) to the lesion’s shape.
- Finalize dose plan.
- Use automatic positioning system whenever possible to minimize procedure time, but manual mode may be used at convenience (Gamma Knife surgery).
- Double check skull and frame measurements and image quality.
- The neurosurgeon, radiation oncologist, and medical physicist have to agree and approve the final plan.
- Use automatic positioning system whenever possible to minimize procedure time, but manual mode may be used at convenience (Gamma Knife surgery).
Radiation Delivery
- Valid radiosurgery protocol is printed and exported to delivery computer.
- The patient is secured in the radiosurgical device and every isocentric position is checked before radiosurgery can proceed.
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