Transient Ischemic Attack



Transient Ischemic Attack







Transient ischemic attack (TIA) is an acute neurologic deficit of vascular origin that clears completely. It usually lasts anywhere from several minutes to an hour, but by current definition remains no more than 24 hours. Recent data indicate that deficits lasting more than 60 minutes, even if symptoms resolve, represent infarctions when studied with MRI. TIAs are a symptom of disease, not a specific disorder. Half to two-thirds of people with thrombotic strokes give a history of a previous TIA, and approximately one-fourth of patients with TIAs will have a stroke within 3 years. Many of these strokes occur within 2 days of the TIA.

The following points should be established in the patient with a TIA.


IS THE TIA DUE TO ARTERIAL DISEASE IN THE CAROTID OR VERTEBROBASILAR TERRITORY?



  • TIAs in carotid distribution. Transient monocular blindness in the eye on the same side as a stenosed internal carotid artery (amaurosis fugax). The patient may report a “shade coming down” over the eye or obscuration that appears like “white steam” over one eye.




    • Transient aphasia.


    • Motor and sensory symptoms in a single extremity (upper or lower), involving face and arm (middle cerebral arteryterritory involvement), or a clumsy (“bear paw”) hand.


  • TIAs in vertebrobasilar distribution. Slurred speech, dizziness, diplopia, ataxia, syncope, loss of consciousness, dysphagia, numbness around lips or face.



    • Hemiparesis and hemisensory loss do not parallel each other in the individual limb as in carotid disease.


    • There may be bilateral motor or sensory deficits from a single lesion.


  • Lacunar or small-vessel thrombotic strokes. Occur abruptly, or in a stuttering fashion over hours or days. There may be a warning. Headache is absent, and risk factors such as hypertension, smoking, hyperlipidemia, and diabetes are usually present.

TIAs in carotid territory usually are associated with severe stenosis, but may be associated with moderate stenosis and ulcerative plaque at the carotid bifurcation in the neck. With carotid symptoms, especially in association with a carotid bruit or decreased carotid pulse, noninvasive carotid evaluation using carotid duplex ultrasound, CT angiography, or magnetic resonance angiography (MRA) are performed to define the vascular anatomy, and to determine whether the patient is a candidate for carotid endarterectomy. Recently stenting of the carotids has emerged, but is still reserved for medically unstable patients with symptomatic disease. Occasionally, traditional cerebral arteriography may be necessary if the vascular anatomy is not well imaged with noninvasive techniques. Remember, the carotid must have a 75% cross-sectional area reduction before the blood flow is decreased significantly. If the TIA is caused by emboli from an ulcerated plaque, stenosis need not be present. There are patients who have an occluded internal carotid with no symptoms at all. Moreover, patients may have a carotid bruit without stenosis and stenosis without a bruit.

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Oct 20, 2016 | Posted by in NEUROLOGY | Comments Off on Transient Ischemic Attack

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