Fusiform Arterial Enlargement
Sheri L. Harder, MD
DIFFERENTIAL DIAGNOSIS
Common
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Dolichoectasia
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Atherosclerotic Fusiform Aneurysm
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Nonaneurysmal Dissection
Less Common
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Dissecting Aneurysm/Pseudoaneurysm
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Vasculitis
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Nonatherosclerotic Fusiform Aneurysm/Vasculopathy
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Neurofibromatosis Type 1
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Systemic Lupus Erythematosus
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Ehlers-Danlos IV
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Marfan Syndrome
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Rare but Important
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Giant “Serpentine” Aneurysm
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Atypical Saccular Aneurysm
ESSENTIAL INFORMATION
Key Differential Diagnosis Issues
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Ectasia = elongated/tortuous artery
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Fusiform aneurysm
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Long segment fusiform arterial dilatation
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Can be acute (dissecting) or chronic (ASVD, nonatherosclerotic vasculopathy)
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Helpful Clues for Common Diagnoses
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Dolichoectasia
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Dilated/elongated arteries ± slow flow
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Vessel layers intact
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Older patients
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Most common manifestation of intracranial ASVD
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Vertebrobasilar > internal carotid artery
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Ectasia often extends into branches
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Atherosclerotic Fusiform Aneurysm
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Thick wall ± organized thrombus
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Variable slow flow
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Nonaneurysmal Dissection
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Vertebral > basilar > internal carotid artery
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Lacks changes of ASVD in other vessels
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Can be spontaneous or traumatic
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Helpful Clues for Less Common Diagnoses
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Dissecting Aneurysm/Pseudoaneurysm
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Focal arterial dilatation
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Trauma = most common etiology
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Next to hard/fixed structures (bone, dura)
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Vasculitis
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Involves multiple vessels
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Alternating stenoses/dilatations
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Nonatherosclerotic Fusiform Aneurysm/Vasculopathy
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Younger patient; history of inherited vasculopathy, immune disorder
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Helpful Clues for Rare Diagnoses
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Giant “Serpentine” Aneurysm
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Large, partially thrombosed mass
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Distal branches arise from aneurysm dome
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Lacks definable neck
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ICA/MCA > vertebrobasilar artery
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Atypical Saccular Aneurysm
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Arises from vessel bifurcations
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Long “aspect ratio” → fusiform appearance
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Often multilobulated, bizarre
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