Educational material
Applied relaxation or other relaxation/de-arousal intervention
Cognitive restructuring for thoughts, beliefs and meta-cognitive beliefs
Scheduled worry time
Problem solving
Worry exposure/behavioural experiments
Interpersonal problem solving and/or communication skills training
Sleep management
Behavioural activation/activity scheduling
Mindfulness
Relapse prevention
Carlbring et al. (2011)
x
(x)*
x
x
x
x
(x)*
(x)*
x
Dear et al. (2011a)
x
x
x
(x)*
(x)*
X
(x)*
(x)*
x
x
Draper et al. (2008)
x
x
x
x
x
x
x
Johnston et al. (2011)
x
x
x
(x)*
(x)*
x
(x)*
(x)*
x
x
Newby et al. (2013)
x
x
x
x
x
x
x
Paxling et al. (2011)
x
x
x
x
x
x
x
x
x
Titov et al. (2013)
x
x
x
(x)*
(x)*
x
(x)*
(x)*
x
x
Titov et al. (2011)
x
x
x
(x)*
(x)*
x
(x)*
(x)*
x
x
Titov et al. (2009a)
x
x
x
(x)*
(x)*
x
(x)*
(x)*
x
x
Effects in Research and Clinic: Results of Research Trials and Clinical Use
The studies described below report published outcomes for ICBT interventions for GAD (see Table 5.2). Studies were included if they evaluated interventions that were designed specifically for treating GAD or designed to target symptoms of GAD in addition to symptoms of other anxiety disorders or depression. All studies included were conducted in either Sweden or Australia. Before discussing the results of these studies, it is helpful to consider issues in diagnosis and measurement of symptoms of GAD.
Table 5.2
Studies of Internet-delivered cognitive behavioural treatments for GAD
Authors (country) | Design | Sample | Results | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Design conditions (n) | Primary outcome measures | Intervention components | Treatment duration | Guidance | N | Diagnostic tool/criteria | Analysis | Total therapist contact | Within-group ES (pre-post d) | Within-group ES (pre-follow-up d) (duration) | |
Draper et al. (2008) (Australia) | Research open trial 1. TG ICBT | (a) GADQ-IV, (b) PSWQ | 11 CBT-based online lessons; occasional telephone calls | 11 weeks | Self-guided | 3 | SCID-IV | ITT/completer | Occasional phone calls to facilitate engagement | – | – |
Titov et al. (2009a) (Australia) | Research RCT 1. TG ICBT 2. WLC | (a) GAD-7, (b) PSWQ | 6 CBT-based online lessons; homework assignments; additional written resources; weekly secure messaging or telephone calls; online discussion forum | 8 weeks | Therapist guided | 45 | MINI | ITT | 130 min | 1. (a) 1.67; (b) 0.98 2. (a) 0.34; (b) 0.02 | – |
Robinson et al. (2010) (Australia) | Research RCT 1. TG ICBT 2. CG ICBT 3. WLC | (a) GAD-7, (b) PSWQ | 6 CBT-based online lessons; homework assignments; additional written resources; weekly secure messaging or telephone calls; automated emails; online discussion forum | 10 weeks | Therapist guided | 145 | MINI | ITT | TG ICBT 81 min; CG ICBT 75 min | 1. (a) 1.55; (b) 1.16 2. (a) 1.73; (b) 1.07 3. (a) 0.38; (b) 0.14 | 1. a) 1.48;b) 1.42 2. a) 1.61;b) 0.97 – (3 months) |
Titov et al. (2010) (Australia) | Research RCT 1. TD TG ICBT 2. WLC | (a) GAD-7, (b) PSWQ | 6 CBT-based online lessons; homework assignments; additional written resources; weekly secure messaging or telephone calls; online discussion forum | 8 weeks | Therapist guided | 78 | MINI | ITT | 46 min | 1. a) 0.81;b) 0.60 2. a) -0.01; b) 0.21 | 1. (a) 0.73; (b).79 (3 months) |
Johnston et al. (2010) (Australia) | Research RCT 1. TG ICBT 2. CG ICBT 3. WLC | (a) GAD-7, (b) PSWQ | 8 CBT-based online lessons; homework assignments; additional written resources; weekly secure messaging or telephone calls; automated emails; online discussion forum | 10 weeks | Therapist guided | 131 | MINI | ITT | TG ICBT 70 min; CG ICBT 69 min | 1. (a) 0.71; (b) 0.81 2. (a) 1.06; (b) 1.17 3. (a) 0.15; (b) 0.02 | 1. (a) 0.57;(b) 0.81 2. (a) 1.18;(b) 1.12 – (3 months) |
Carlbring et al. (2011) (Sweden) | Research RCT 1. IT TG ICBT 2. AC | (a) BAI, (b) MADRS-S | Participants prescribed 6 to 10 CBT-based online modules based on existing ICBT interventions for panic disorder, social phobia, GAD and depression | 10 weeks | Therapist guided | 54 | SCID-I | ITT | 85 min | 1. (a) 1.12; (b) 1.21 2. (a) 0.44; (b) 0.46 | 1. (a) 1.23;(b) 1.31 (Entire sample 2 years) |
Titov et al. (2011) (Australia) | Research RCT 1. TD TG ICBT 2. WLC | (a) GAD-7, (b) PSWQ | 8 CBT-based online lessons; homework assignments; additional written resources; weekly secure messaging or telephone calls; online discussion forum | 10 weeks | Therapist guided | 74 | MINI | ITT | 85 min | 1. (a) 0.92; (b) 0.68 2. (a) 0.22; (b) -0.08 | 1. (a) 0.94;(b) 0.63 (3 months) |
Dear et al. (2011a) (Australia) | Research open trial 1. TD TG ICBT | (a) GAD-7, (b) PSWQ | 5 CBT-based online lessons; homework assignments; additional written resources; weekly secure messaging or telephone calls; online discussion forum | 8 weeks | Therapist guided | 32 | MINI | ITT | 45 min | 1. (a) 1.06; (b) 0.84 | 1. (a) 0.95;(b) 0.90 (3 months) |
Paxling et al. (2011) (Sweden) | Research RCT 1. TG ICBT 2. WLC | (a) PSWQ | 8 online treatment modules based on Paxling et al. (2011), weekly homework assignments, weekly secure messaging with therapist | 8 weeks | Therapist guided | 89 | GADQ-IV | ITT | 113 min | 1. (a) 1.08 2. (a) -0.01 | 1. (a) 1.66 (12 months); (a) 1.40 (3 years) |
Klein et al. (2011) (Australia) | Clinical open trial 1. SG ICBT | (a) GAD-CDSR | 12 CBT-based online lessons; homework tasks, delivered in a fully automated system | 12 weeks | Self-guided | 88 | Online diagnostic system/at least subclinical levels of GAD | Completers (88/704) | Nil | (a) 1.22 | – |
Andersson et al. (2012) (Sweden) | Research RCT 1. TG ICBT 2. TG IPDT 3. WLC | (a) PSWQ | 1. 8 online treatment modules based on Paxling et al. (2011), weekly homework assignments, weekly secure messaging with therapist 2. 8 online chapters based on Make the Leap, self-help book and recommended writing assignments, weekly secure messaging with therapist | 8 weeks | Therapist guided | 81 | SCID-I | ITT | TG ICBT 92 min; IPDT 113 min | 1. (a) 0.87 2. (a) 1.16 3. (a) 0.72 | 1. (a) 1.88 2. (a) 1.92 3. – (18 months) |
Mewton et al. (2012) (Australia) | Clinical open trial 1. TG ICBT | (a) GAD-7 | 6 CBT-based online lessons; homework tasks, unspecified support from external health professional | 11 weeks | Therapist guided | 588 | N/A | Completers (324/588) | Not described | (a) 0.91 | – |
Kirkpatrick et al. (2013) (Australia) | Clinical open trial 1. TG ICBT | (a) GAD-7, (b) PHQ-9 | 5 CBT-based online lessons; homework assignments; additional written resources; weekly telephone calls | 8 weeks | Therapist guided | 10 | GAD-7 ≥ 5 | ITT | Not described | 1. (a) 1.07; (b) 1.76 | 1. (a) 1.61;(b) 2.17 (2 months) |
Newby et al. (2013) (Australia) | Research RCT 1. TD TG ICBT 2. WLC | (a) GAD-7, (b) PSWQ | 6 CBT-based online lessons; homework assignments; additional written resources; weekly secure messaging or telephone calls | 8 weeks | Therapist guided | 99 | MINI | ITT | 24 min | 1. (a) 0.96; (b) 0.87 2. (a) 0.07; (b) 0.01 | Not reported (3 months) |
Newby et al. (2013) (Australia) | Clinical open trial 1. TD TG ICBT | (a) GAD-7, (b) PHQ-9 | 6 CBT-based online lessons; homework tasks, unspecified support from external health professional | 8 weeks | Therapist guided | 136 | N/A | ITT | Not described | 1. (a) 1.05; (b) 0.94 | – |
Research RCT 1. SGE ICBT 2. SG ICBT 3. WLC | (a) GAD-7, (b) PHQ-9 | 5 CBT-based online lessons; homework assignments; additional written resources; weekly secure messaging or telephone calls | 8 weeks | Self-guided | 257 | GAD-7 ≥ 8, or PHQ-9 > 10, or MINI-SPIN ≥5, or ANSQ ≥1 | ITT | Nil | 1. (a) 1.08; (b) 0.96 2. (a) 0.76; (b) 0.68 3. (a) 0.14; (b) 0.02 | 1. (a) 1.08;(b) 1.10 2. (a) 1.01;(b) 0.98 (12 months) |
Diagnosis and Measurement of GAD
It should be noted that several strategies have been used in studies of ICBT for GAD to identify people with clinical or subclinical levels of GAD. These include manually administered clinical interviews, automated structured diagnostic interviews, or cut-off scores based on responses to standardised questionnaires which are usually administered online. Where possible, these different criteria are noted below.
With respect to measurement of symptoms and severity of GAD in trials of ICBT, most studies have reported the use of the Penn State Worry Questionnaire (PSWQ) (Meyer et al. 1990) or the Generalized Anxiety Disorder 7-Item Scale (GAD-7) (Spitzer et al. 2006). The PSWQ consists of 16 items and is considered a valid clinical measure of worry characteristic of GAD. Early psychometric evaluations revealed the PSWQ had high internal consistency and temporal stability (Meyer et al. 1990) and was able to differentiate patients with GAD from those with other anxiety disorders (Brown et al. 1992). The GAD-7 is an increasingly popular measure of symptoms of GAD, which comprises seven items from the DSM-IV criteria for GAD. Psychometric evaluations of the GAD-7 indicate it is sufficiently sensitive to detect GAD, panic disorder, social phobia and post-traumatic stress disorder. A recent psychometric comparison of the PSWQ and GAD-7 revealed a moderate correlation between the two scales, and both were sensitive to change, although the GAD-7 appeared to be more sensitive and may, therefore, confer some advantages in clinical work (Dear et al. 2011b).

Stay updated, free articles. Join our Telegram channel

Full access? Get Clinical Tree

