Authors and year
Type
Number of patients (sex)
Age (mean)
Location
Symptoms
Treatment
Outcomes
Follow-upperiod
Ataizi et al. (2007)
Case report
1 (F)
28
C5–T1
Neck and back pain
Conservative (patient refused surgery)
Resolution of pain Spontaneous collapse of syrinx
16 months
Bogdanov et al. (2004)
(Note 1)
Cross-sectional
17 (2 F, 15 M)
49
Cervical
Segmental sensory loss
Pyramidal signs Muscle atrophy
Not applicable
Not applicable
Not applicable
Chen et al. (2004)
Case report
1 (F)
19
C2–C6
Proximal upper limb weakness
Diminished pain and temperature sensation
Suboccipital craniectomy + C1 and C3–C5 laminectomies
Improved strength Sensory deficit unchanged
Syrinx reduced
12 months
Chern et al. (2011)
Retrospective case series
15 (6 F,9 M)
11
Multiple
Scoliosis
Headache
Neck pain
Suboccipital craniectomy + C1 laminectomy
Resolved – 4
Improved – 6
Stable – 3
Worse – 1
12–75 months
Holly and Batzdorf (2002)
(Note 2)
Prospective study
32 (14 F, 18 M)
40
Cervical (16 cases)
Thoracic (12 cases)
Cervical-thoracic (4 cases)
Mechanical spinal pain
Radicular pain Numbness
Anterior fusion C6–C7 (1 patient)
Conservative (31patients)
Improved – 6
Unchanged – 19
Worse – 7
6–110 months (mean 38)
Jinkins and Sener (1999)
Case series
3 (2 F, 1 M)
27
Lumbar
Cervical
Thoracic
Low back pain
Headache
Conservative
Stable with resolution of pain in 2 patients
2–4 years (mean 3)
Kastrup et al. (2001)
Case report
1 (F)
61
C1–conus
Burning pain
Carbamazepine
Subsequent collapse of syrinx
Symptoms unchanged
8 years
Kyoshima et al. (2002)
(Note 3)
Retrospective case series
4 (3 F, 1 M)
38
Whole or near whole cord
Impaired touch and pain sensation
Weakness
Hypoalgesia
Craniocervical decompression
Improved symptoms in all
Syrinx decreased in all but 1 case
2.5–11years (mean 8)
Lin et al. (2006)
Case report
1 (M)
35
T2–T9
Leg weakness
Reduced touch and pinprick
T6–T8 laminectomy + shunt (syringosubarachnoid)
JOA score a improved from 10 to 14 at day 30 post-op
30 days
Magge et al. (2011)
Retrospective case series
48 (30 F,18 M)
10
2–17 levels; mostly thoracic
Scoliosis, Cutaneous stigmata
Leg or back pain (neurological symptoms were judged to be incidental)
Shunt (syringosubarachnoid) (1 patient)
Fenestration of syrinx (1 patient)
Conservative (remainder)
Operated cases: weakness and worsened gait (1st case) No change (2nd case)
Clinical: 3–56 months (mean 15.5)
Radiographic: 2–64 months (mean 23.8)
Mallucci et al. (1997)
Retrospective case series
10 (2 F, 8 M)
48
Not described
Sensory disturbance weakness
Laminectomy and excision of web/cyst, Shunt (syringosubarachnoid) (2 patients)
Improved symptoms and syrinx reduced except for the 2 shunted cases
Not described
Mauer et al. (2008)
(Note 1)
Prospective case series
125 (76 F,49 M)
36
1–18 levels not clearly defined
No surgery: Pain + sensory impairment
With surgery: Bowel/bladder dysfunction, gait problems Paralysis
Arachnoid scar or web resection (10 patients)
Conservative (115 patients)
Surgery: 4 improved, rest stabilised
Conservative: outcomes not described
Not described
Nakamura et al. (2009)
Retrospective case series
15 (4 F, 11 M)
45
Localised C3–T2 (12 cases)
Extended C1–T8 (3 cases)
Upper limb numbness
Neck pain, 3pts extended: also progressive upper limb weakness
Conservative (12 patients)
Shunt (syringosubarachnoid) (3 patients)
Conservative: no changes
Surgical cases: reduced syrinx and mean JOA a decreased
7–20 years (mean 10)
Porensky et al. (2007)
Case report
2 (M)
43y and 44y
T1–T2 and C5–T5
Ataxia