Platyspondyly, Diffuse



Platyspondyly, Diffuse


Julia Crim, MD



DIFFERENTIAL DIAGNOSIS


Common



  • Multiple Myeloma


  • Osteoporosis


  • Sickle Cell


  • Scheuermann Disease


Less Common



  • Metastases, Lytic Osseous


  • Osteogenesis Imperfecta


  • Mucopolysaccharidoses


Rare but Important



  • Spondyloepiphyseal Dysplasia


  • Ehlers-Danlos Syndrome


  • Achondroplasia


  • Cushing Disease


  • Thanatophoric Dwarfism


  • Gaucher Disease


ESSENTIAL INFORMATION


Key Differential Diagnosis Issues



  • Uncommon condition irrespective of cause


  • In adults, usually due to severe osteoporosis or myeloma



    • Compression fractures may be so extensive that they cause uniform flattening at all levels


    • More commonly, amount of vertebral height loss varies from level to level


    • Metastases uncommonly show uniform platyspondyly


  • Dwarfisms show limb abnormalities also


  • Connective tissue disorders show scalloping of posterior vertebral body margin



    • Due to dural ectasia


Alternative Differential Approaches

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Aug 7, 2016 | Posted by in NEUROLOGY | Comments Off on Platyspondyly, Diffuse

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