Platyspondyly, Diffuse

Platyspondyly, Diffuse

Julia Crim, MD



  • Multiple Myeloma

  • Osteoporosis

  • Sickle Cell

  • Scheuermann Disease

Less Common

  • Metastases, Lytic Osseous

  • Osteogenesis Imperfecta

  • Mucopolysaccharidoses

Rare but Important

  • Spondyloepiphyseal Dysplasia

  • Ehlers-Danlos Syndrome

  • Achondroplasia

  • Cushing Disease

  • Thanatophoric Dwarfism

  • Gaucher Disease


Key Differential Diagnosis Issues

  • Uncommon condition irrespective of cause

  • In adults, usually due to severe osteoporosis or myeloma

    • Compression fractures may be so extensive that they cause uniform flattening at all levels

    • More commonly, amount of vertebral height loss varies from level to level

    • Metastases uncommonly show uniform platyspondyly

  • Dwarfisms show limb abnormalities also

  • Connective tissue disorders show scalloping of posterior vertebral body margin

    • Due to dural ectasia

Alternative Differential Approaches

Aug 7, 2016 | Posted by in NEUROLOGY | Comments Off on Platyspondyly, Diffuse
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