Vertebral Endplate Contour Abnormality



Vertebral Endplate Contour Abnormality


Julia Crim, MD



DIFFERENTIAL DIAGNOSIS


Common



  • Schmorl Node


  • Degenerative Endplate Changes


  • Limbus Vertebra


  • Anterior Compression Fracture


  • Lateral Compression Fracture


  • Scheuermann Disease


  • Osteomyelitis, Pyogenic


  • Sickle Cell


Less Common



  • Neurogenic (Charcot) Arthropathy


  • Osteomyelitis, Granulomatous


  • Cushing Disease


  • Osteogenesis Imperfecta


  • Achondroplasia


  • Mucopolysaccharidoses


  • Thanatophoric Dwarfism


  • Spondyloepiphyseal Dysplasia


ESSENTIAL INFORMATION


Key Differential Diagnosis Issues



  • May be due to trauma, developmental or congenital disorders, degenerative disease or infection


Helpful Clues for Common Diagnoses



  • Schmorl Node: Cup-shaped defect in endplate


  • Degenerative Changes: Osteophytes may elongate or form hook adjacent to endplate


  • Limbus Vertebra: Small separate corner portion of endplate, well-marginated


  • Fracture: Angular deformity of endplate, ± visible fracture line


  • Scheuermann Disease: Undulating endplates 4 or more levels + kyphosis, with or without discrete Schmorl nodes


  • Osteomyelitis: Endplate erosion, vertebral body destruction, osteopenia or osteosclerosis


  • Sickle Cell: Depression central portion of endplate (“Lincoln Log”)


Helpful Clues for Less Common Diagnoses



  • Neurogenic Arthropathy: Mimics osteomyelitis; endplate destruction and erosion, nonunited fracture fragments, heterotopic ossification


  • Osteomyelitis, Granulomatous: Vertebral endplate destruction and deformity, but disc spaces preserved until late; may involve multiple levels; bone fusion and kyphosis


  • Cushing Disease: C-shaped endplate (“fish mouth”)


  • Osteogenesis Imperfecta: Variable flattening and deformity due to fractures; severe osteopenia


  • Achondroplasia, Mucopolysaccharidoses: Anterior beak deformity


  • Spondyloepiphyseal Dysplasia: Vertebrae flattened but taller in center than at sides

Aug 7, 2016 | Posted by in NEUROLOGY | Comments Off on Vertebral Endplate Contour Abnormality

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