Fracture, Vertebral Body
Julia Crim, MD
DIFFERENTIAL DIAGNOSIS
Common
Vertebral Body Only
Anterior Compression Fracture, Thoracic
Anterior Compression Fracture, Lumbar
Lateral Compression Fracture, Lumbar
Lateral Compression Fracture, Thoracic
Burst Fracture (Mild)
Pathologic Vertebral Fracture
Hyperflexion Injury, Cervical
Hyperextension Injury, Cervical
Vertebral Body Plus Posterior Elements
Burst Thoracolumbar Fracture
Burst Fracture, Lumbar
Burst Fracture, Cervical
Pathologic Vertebral Fracture
Burst Fracture, C2
Hyperflexion Injury, Cervical
Hyperextension Injury, Cervical
Chance Fracture, Thoracic
Distraction Fx, Low Thoracic
Fracture Mimics
Schmorl Node
Limbus Vertebra
Kyphosis, Idiopathic
Scheuermann Disease
Sickle Cell
Scoliosis and Kyphosis, Congenital
Neurogenic (Charcot) Arthropathy
Osteomyelitis, Pyogenic
Less Common
Lymphoma
Cushing Disease
Kümmell Disease
Osteomyelitis, Granulomatous
Congenital Syndromes
Failure of Vertebral Formation
Osteogenesis Imperfecta
Diastematomyelia
Achondroplasia, Mucopolysaccharidoses
Mucopolysaccharidoses
Rare but Important
Ewing Sarcoma
Apophyseal Ring Fracture
ESSENTIAL INFORMATION
Key Differential Diagnosis Issues
Mechanism of injury
Compression, burst: Axial load injuries
Chance: Anterior compression, posterior distraction
Fracture/dislocation: Shear forces
Treatment of different types of fractures is different, so imaging distinction is important
Imaging may overestimate or underestimate mechanical instability of spine
Fracture vs. fracture mimic
History of trauma may not be available or reliable
Fractures may be single or multiple levels
May have different kinds of fractures at different levels
e.g., burst and compression at 2 different levels
Multiple, uniformly involved levels of deformity usually not traumatic
Helpful Clues for Common Diagnoses
Compression Fracture
Does not involve posterior vertebral body cortex or posterior elements
Common throughout thoracic and lumbar spine
May involve anterior or lateral portion of vertebral body
Often occur at multiple levels in normal or osteoporotic bone
Most common type of pathologic fracture
Burst Fracture
Burst fracture extends through posterior cortex of vertebral body
More severe burst fractures show vertically oriented fractures of neural arch
Most common at thoracolumbar junction
Chance Fracture
Anterior compression vertebral body
In conjunction with horizontally oriented fracture of posterior elements OR ligamentous injury resulting in separation of adjacent spinous processes
Most common at thoracolumbar junction
Hybrid Fractures
Some fractures have elements of both burst- and chance-type injury
Retropulsion of posterior vertebral body cortex + separation of posterior elements
Best to categorize as Chance and add description of burst elements
Compression or Burst Fracture due to Trauma or Osteoporosis
MR: Band-like configuration of abnormal signal
CT: Trabeculae compressed but not destroyed
Compression or Burst Fracture due to Tumor
Radiographic findings
Focal osteopenia or osteosclerosis
Cortical destruction
Nonvisualization of pedicle contour on AP radiograph a helpful sign
MR findings
Rounded configuration of abnormal signal, or diffuse abnormal signal adjacent to fracture
Cortical breakthrough beyond fracture line is often seen
Additional areas of abnormal signal without fracture helpful signs when present
CT findings
Destruction of trabeculae adjacent to fracture
Cortical break beyond fracture line is often seen
Additional areas of bony destruction without fracture helpful signs when present
Limbus Vertebra
Ossicle anterior corner of vertebral body, smoothly contoured & corticated
Failure of fusion of ring apophysis
Kyphosis, Idiopathic
Smooth vertebral endplate contour, multiple vertebrae
Diagnosis of exclusion
Scheuermann Disease
Undulating contour of endplates
Discrete Schmorl nodes variably present
4 or more contiguous vertebral bodies with at least 5° wedging each
Sickle Cell
H-shaped or “Lincoln Log” vertebrae with central depression and preserved margins
Infection or Neuropathic Arthropathy
Endplate destroyed, irregularStay updated, free articles. Join our Telegram channel
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