Intradural Lesion, Serpentine
Jeffrey S. Ross, MD
DIFFERENTIAL DIAGNOSIS
Common
CSF Flow Artifact
Vascular Malformation, Type 1
Vascular Malformation, Type 2
Redundant Roots due to Thecal Sac Compression
Central Stenosis
Herniation (Uncommon)
Less Common
Tumor Feeding Vessels
Hemangioblastoma, Spinal Cord
Ependymoma, Myxopapillary, Spinal Cord
Paraganglioma
Schwannoma
Hereditary Motor/Sensory Neuropathy
Collateral Veins/IVC Occlusion
Vascular Malformation, Type 3
Vascular Malformation, Type 4
Brain Dural A-V Fistula
ESSENTIAL INFORMATION
Helpful Clues for Common Diagnoses
CSF Flow Artifact
Related to both time-of-flight (TOF) effects and turbulent flow
TOF signal loss seen with SE or FSE when protons do not experience both initial RF pulse and subsequent refocusing pulse
Increased signal loss with higher flow velocity, thin slices, longer TE, imaging perpendicular to flow
GE imaging less susceptible to CSF flow artifacts
Turbulent flow leads to more rapid proton dephasing with signal loss
Repeat study with different plane of imaging, and GE sequences with short TE
Vascular Malformations
Most common is type 1 dural fistula
Lesions are extramedullary AVFs, not true AVMs
Venous drainage from the DAVF results in increased pial vein pressure that is transmitted to intrinsic cord veins
Venous hypertension from engorgement reduces intramedullary AV pressure gradient, causing reduced tissue perfusion & cord ischemia
Hallmark is T2 hyperintense cord (usually distal thoracic), intradural flow voids on cord surface, esp. dorsal
Redundant Roots due to Thecal Sac Compression
Seen with severe central canal stenosis or, much less commonly, large herniation
Typically seen cephalad to level of severe stenosis
Helpful Clues for Less Common Diagnoses
Tumor Feeding Vessels
Associated with vascular tumor such as ependymoma or hemangioblastoma
Look for primary enhancing soft tissue mass
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